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Summary Expression Gene Literature (619) GO Terms (28) Nucleotides (124) Proteins (45) Interactants (642) Wiki
XB-GENEPAGE-484854
Gene Symbol:
gli3

Gene Name:
GLI family zinc finger 3

Synonyms:
XGli-3 , Xgli3 ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger, C2H2 type; hedgehog signaling

Protein Function :
Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and may play a role in limb development. May bind to the minimal GLI-consensus sequence 5'-GGGTGG...[+]


InterPro :
AN1-like Znf , Znf AN1 , TFR-like dimer dom , Peptidase M28 [+]

Interactants:
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Diseases: 


Disease Ontology:
polydactyly [+]

OMIM:
ACROCALLOSAL SYNDROME; ACLS [+]

External Links:
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Xenbase Gene ID XB-GENE-484855 XB-GENE-865509 XB-GENE-17346222
Gene Symbol gli3 gli3.L gli3.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100101789
397837
108720004
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide