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Summary Expression Phenotypes Gene Literature (117) GO Terms (144) Nucleotides (141) Proteins (57) Interactants (620) Wiki
XB-GENEPAGE-484854
???displayGene.symbol???:
 gli3

???displayGene.name???: 
GLI family zinc finger 3

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XGli-3 , Xgli3 ( Nomenclature history )

???displayGene.geneFunction???
zinc finger, C2H2 type; hedgehog signaling

Protein Function :
Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and may play a role in limb development. May bind to the minimal GLI-consensus sequence 5'-GGGTGG...[+]


InterPro :
GLI-like, Znf C2H2 sf, Znf C2H2 type

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Diseases: 


Disease Ontology:
esophageal atresia/tracheoesophageal fistula [+]

MIM:
ACROCALLOSAL SYNDROME; ACLS [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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