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Summary Expression Gene Literature (68) GO Terms (27) Nucleotides (154) Proteins (51) Interactants (700) Wiki
XB-GENEPAGE-484864
Gene Symbol:
sox17b.1

Gene Name:
SRY (sex determining region Y)-box 17 beta, gene 1

Synonyms:
Xsox17-beta , sox17-beta , tSox17beta , Sox17beta , sox17 , Xsox17 ( Add synonyms , Nomenclature history )

Gene Function:
HMG-box transcription factor

Protein Function :
Transcription activator. Doesn't appear to bind to the consensus 5'-AACAAT-3' DNA binding site, but binds 5'-ATTGTT-3'. All of the sox17 proteins are required for embryonic endoderm development and gas...[+]



Interactants:
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Diseases: 


Disease Ontology:
vesicoureteral reflux

OMIM:
VESICOURETERAL REFLUX 3; VUR3

External Links:
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Xenbase Gene ID XB-GENE-484865 XB-GENE-865510 XB-GENE-6252148
Gene Symbol sox17b.1 sox17b.1.L sox17b.1.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 394440
100049782
397967
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sox17b.1 sox17b.1.L sox17b.1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, GeneCards SOX17 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
rat
zebrafish
chicken
fruit fly
worm
Publications
First Mixer, a homeobox gene required for endoderm development., Science 1998  
Most Recent Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network., Elife 2020                        
All View All Papers 14 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 4 terms 12 terms
PANTHER sox17b.1
KEGG Pathways K04495 K04495 K04495
KOG [K] HMG-box transcription factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sox17b.1
Antibodies Sox17a/b Ab2 , Sox17b Ab1 Sox17a/b Ab2 , Sox17b Ab1 Sox17a/b Ab2 , Sox17b Ab1
Morpholinos sox17b.1 MO1 , sox17b.1/b.2 MO1 sox17b.1 MO1 , sox17b.1/b.2 MO1 sox17b.1 MO1 , sox17b.1/b.2 MO1
ORFs sox17b.1.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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