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Summary Expression Gene Literature (71) GO Terms (29) Nucleotides (154) Proteins (51) Interactants (727) Wiki
XB-GENEPAGE-484864
Gene Symbol:
sox17b.1

Gene Name:
SRY (sex determining region Y)-box 17 beta, gene 1

Synonyms:
Xsox17-beta , sox17-beta , tSox17beta , Sox17beta , sox17 , Xsox17 ( Add synonyms , Nomenclature history )

Gene Function:
HMG-box transcription factor

Protein Function :
Transcription activator. Doesn't appear to bind to the consensus 5'-AACAAT-3' DNA binding site, but binds 5'-ATTGTT-3'. All of the sox17 proteins are required for embryonic endoderm development and gas...[+]


InterPro :
TPR-like helical dom sf , HAT , Suf , Sox C [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
vesicoureteral reflux

OMIM:
VESICOURETERAL REFLUX 3; VUR3

External Links:
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Xenbase Gene ID XB-GENE-484865 XB-GENE-865510 XB-GENE-6252148
Gene Symbol sox17b.1 sox17b.1.L sox17b.1.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394440
100049782
397967
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sox17b.1 sox17b.1.L sox17b.1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, GeneCards SOX17 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
rat
zebrafish
chicken
fruit fly
worm
Publications
First Mixer, a homeobox gene required for endoderm development., Science 1998  
Most Recent Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., EMBO J 2021                          
All View All Papers 14 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 4 terms 12 terms
PANTHER sox17b.1
KEGG Pathways K04495 K04495 K04495
KOG [K] HMG-box transcription factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sox17b.1
Antibodies Sox17a/b Ab2 , Sox17b Ab1 Sox17a/b Ab2 , Sox17b Ab1 Sox17a/b Ab2 , Sox17b Ab1
Morpholinos (on-target & off-target) sox17b.1/b.2 MO1 sox17a MO3 , sox17b.1/b.2 MO1 sox17a MO3 , sox17b.1 MO1
ORFs sox17b.1.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info