sox17b.1 Summary [species: Xenopus laevis and Xenopus tropicalis]

Transcription activator. Doesn't appear to bind to the consensus 5'-AACAAT-3' DNA binding site, but binds 5'-ATTGTT-3'. All of the sox17 proteins are required for embryonic endoderm development and gas...[+]

InterPro

TPR-like helical dom sf , HAT , Suf , Sox C [+]

Interactants:

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Diseases:

Disease Ontology:

vesicoureteral reflux

OMIM:

VESICOURETERAL REFLUX 3; VUR3

External Links:

MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD

1/6

Xenbase Gene ID

XB-GENE-484865

XB-GENE-865510

XB-GENE-6252148

Gene Symbol

sox17b.1

sox17b.1.L

sox17b.1.S

Chromosome

Chr6

chr6L

chr6S

Molecules

X. tropicalis

X. laevis.L

X. laevis.S

Genomic Sequence

Version 9.1

>sox17b.1 9.1 
							GATCAGTAGCCAGTGAGCTGTACCTGTAGCGCTACTCTCCTCACCATGAGCAGCCCAGATGGTGGCTACGCCAGCGATGATCAAATTCATGGAAACTGCTCAGTGCCAATCATGATGGGCCAGTACGAATGGACCGACCCCCTGACCATGTTTCAGGATGCCAAAACGAAGAAAGAGGCTGGATCTGCCAATTCCAGGGGCAAAGCCGAAGCTCGGATCCGCCGACCCATGAATGCGTTTATGGTGTGGGCAAAGGACGAGCGCAAGAGGCTGGCACAGCAGAACCCGGACCTGCACAACGCGGAGCTCAGCAAGATGCTCGGTAAGGGGGCTCTGGGGCAACTGTGGGGTGGAAATATGGCTACTATGGCTACTACTGGGCCTGTGCCAGCATTGCTTGGCTGTACGGGGCATATTCTGTAAGGCTTAGACCTTTACCGGGAGTGGGGGGTTTAGTATTATGTGATAAACATAGTTGGGCCCTGGGTCCCCGGTACGGGCCGTGTGCGGTCCCGGTTTTCCGTTTTATGAGGAAAAAAGATTGGGTCCAACATGGTTTCGATGCCTTTCTCTCCTGCCTGAAATCTGGACCCGACTTTTCACTCAGTGGGGATGTAAGTGAAGATTAGCTGGATAATGCAGTTGGAACAACTAAATTTGTCTAATGAAACAGAATGTAATGCAACACAACTTTCCCATATACACGTATGTATTGTCTGTCCCTGCAGTATATTCTGACTTTTACCAAGTCTCGTATTAACTGTccattgctacattgtttcagtagtgaGAGCCAGCAGTGAGAGGTATAGCAAGGGACAGACACTTATTGCTcacagtagcaattacatttacaaaatacatttgaaaccaccaatttgtaattaatatatattgggaTATATTGTCTTtttatgcaaattattttttttattctgtatttattattagaacGTCCACTGACTATACAGCTGTTGCTTTACCAAATATTGCAATATTGCACCTGTGTCTCTGCTTTAATGTATTATGCCCAGTAACTAACCAGTACTCTCTTCTGTAGGCAAATCATGGAAATCTCTGACTTTGGCATCCAAACGGCCCTTCGTGGAGGAAGCTGAGAGGCTGAGGGTGCAGCACATTCAGGACTATCCTGATTACAAGTACAGACCACGCAGGAAGAAGCAAGTGAAGAGGATGAAGAGGGAAGAGGAAGGCTTCCTCCCCAGTGCAAACTTAGCAGGACCACAAGTGATGGGCTGCAATGCCATGGTAGGGCAGAACTACAAGATGCAGTATTCTGGGCAGAACAGCCAGCAGAGCCAAATCACACCAGCAGGCTATTTTGAGGACCACAACCCAGTGGGATACTATTACAGAGGTTACAATGTTTCCAAATACTATATGTCCCAGAACAGCTCTGGCtactgcagccctccagctcaGGGAGAGTACCAGGCACTGTCATATAATTTCAACAGCAGCTATATGCCCTACCAGCAGAATGCTTCTACCCCAGCAATGGGTAAACAGATGGCAGTTAAGGAGAACATTATCCAGGAGAGCCCTGAACATGGCATAATGGGGTGCCAGGTATCTCCACAAATGTACAATGGACAGATGTATGTGCCTGAGTGTGCCAAAACCCACCCAGTGGCACAAACTGAGCAGCATTCCTCTTCGCATCAGTCCCAGCAGATGGTGACACAGAATTACCTACCATCCCAGCAAGATGGGCATCTGGAAAGTGACATTGATAAGACTGAGTTTGACCAGTACCTTATGTATGAGCCCAAGTCTGATACAGAGCTCATCTATACCATTGACCAGGAcagtggtgcctatagtaccaacCTCCTGCCATCTTTAATCTCTGAGGCAAACAGTGTCTGCTACTACGACTATTGCGGAGTATGAAGCACTTGCATTGAGCAGCCTGTAACCAAATGGACAATAATGTAGTTGGGCTTTCTGTGCTATACTTATAGGACTCAAGCTAGTATATTCACTCTTGTAGATGTGATATGTATCATATTGTATATTTCGTATATTATTTTGTAGAGATGGCaaaatttatttacatttaataaatgtactATCATTTGTATAA

Version 9.2

>sox17b.1.L 9.2 
							CCCAAAGTGGAGAGATCCCTGGACCTGTAGCGCCGAACTCCACTaacctcctcctcatcatcatgaGCAGCCCAGACTGTGGCTACGCCAGCGACGATCAAATTCAGAGAAGCTGCTCACTACCAATGATGATGGGCCAGTACCAATGGACCGAACCCAGGACCGTCTTTCAGGAAGGCAAACCGAAGAGAGACGAAGTATCCGCCAATTCTAGGAGCAAAGCCGAGGCTCGGATCCGCCGGCCTATGAATGCCTTCATGGTGTGGGCAAAGGACGAGCGCAAGAGACTGGCACAGCAGAACCCCGACCTGCACAACGCCGAGCTCAGCAAGATGCTTGGTAAGGGGGGTCTCGGGCAATTGGTGAGGGGGGTCTCGGGCAATTGGTAACGGGGGTCCCGGGCAATTAGTATTAGTTCTTTGTCGGTTCGGGCccctcttcaggacttcagtacTAGACAATAATAAATGTCCATATGGGGGAAAATCCAGGTCCTATATGATAAAAACGTTGAACTCACCTTTTACACTTTCAGGCAACAAAATACaaagcatatatatattgtatataacttAGCCATTTTAGGACTTTTTGAAACTTGCATTCAGCAGTAGCATTTTCTAtcccttctgctacattgtttcgaTTGTCAGTACCAGCAATGCAGGGTATAGCAAGGGACAGttgcaagggaaagttgtgctcaccactaatttttaaaacctatgctcaattttcatctgattcattaagaattctattgcttcattatacattttacaaagggactaaattttacctgcaacttactagctcaCACCcctcccaactatagtcaggtgatcccactgttgggatgggagggtgggagggcagccaagtttgggcgtaagttgcaggtaaaacttagtccctagTGTAGTTGTTTTGCCCCAATATTGCATATGTACCTTTTCTTTAAGTAAAAATAACTGTTATTCAGTCAGTTCCTAACCAGTACTGTTTTCTTCAGGTAAATCATGGAAATCCCTTAACCTGGCAACAAAACGCCCCTTTGTGGAGGAAGCTGAGAGGCTGAGGGTGCAACACATCCAGGACTATCCCGATTACAAATACAGACCCCGCAGGAAGAAGCAGGTGAAGAGGATGAAGAGGGAAGAGGAGTGCTTCTTTCCAAGTGCAAACATCCCTGGACCTGAGGCGATGGTCAACAATGTCATGGTAGGACAGAAATACAAGATGCAGTATTCTGTGCAGAACCTCCAGGAGAACCAACTCCCCACAGCAGGCTACTTCGAGGGCCACAGCCCCATGGGATACTTTTACAAAGATTACGATGTACCCAATTACTACACTTCCCAGAACAGCTCTGGCTACTGTAGCCCCCCTACTCAAGATGAGTACCAAGCACTGTCTTATGGCTTCGGCAGCAGCTATATGCCCTACCAGCAGACTACTACGACCCCAGTGATGGCTAAACAGATTTCAGTTACTCAGAACATTCCCCAGGAAAGTCCTGAACATGGCATGATGGCATCTCCACAAATGTATAATGGACAAATGTATTTGCCTGAGTGTGCCAAAACCCACCCAGTGGCACAAACTGAGCAGCATTCCCCTTCACATCAGTCCCAGCAGATGGTGAGTCAGAATTATCTACAGTCCCAACAAGATGGACACCTAGAGACTGACATTGACAAGACTGAGTTTGACCAGTACCTTATGTATGAGCCCAAGTCTGATCCAGAGCTCATCTATACCATTGACCAGGACAGTGGGCCTTATAGTACAAACCTCCTGCCATCTTTAATCTCAGAGGCAAACAATGTCTGCTACTATGACTATTGTGGAGTATAAAGCACCTGCACAGACAAATAAGCTAATGGACATTAATGTGTACTCTGTGCTATGGCTTAGAGCTCTAACTATTTCTTTTAGTCACTCTTGTGGATGTGATATGTATCATattgtatattaaatacattattttgaaaGTTTGGcagaatttatttacatttaataaatgtactaTGAATTGTATAA

Version 9.2

>sox17b.1.S 9.2 
							GAGATCTGCGGCTAGTAACGTGTCCCTCTAGCGCTGCTAATCTCCACTAATCGCTGCTAATCACCACAGCACTCCGAATCATGAGCAGCCCGGACTGCGGCTACTCCAGCGACGATCAGATTCAGGGAAGCTGCTCAGTGCCGATGATGATGGGCCAGTATCAATGGACCGAACCCCTGACCGTGTTTCAGGACCTCAAACCCAAGAGGGATGAAGGATCTGCCGATTCCAGAAGCAAAGCCGAGGGTCGGATCCGCCGACCCATGAATGCCTTTATGGTGTGGGCAAAGGACGAGCGCAAGAGGCTGGCGCAACAGAACCCCGACCTGCACAACGCCGAGCTCAGCAAGATGCTTGGTAAGGACTGGCTCTATTATGGGGGTGACTTATTTCTctactgtgttatagaatggcaatttctaagaaactttacaattggttttcattgtttattttttaaaagttttttttaataatttgcttttttgactttttttccagctttaaaatgggggtcactgaccccatctaaaacaaatactctgtaaaactacagacatattgttattgctactttttacgactcatctttctattcaggtcctgtcCCATTCGTTTTCccctctcttattcaactcaatgcatggttgctatggtcatttggaccccagcaactctctacatcatactaaaagtcaactcaaaggtgaacaacccctttaaatgacattGTATTTCTGCAAAAAGTCAGTTCAGGTCCCACTTCAGGACTAGACAATAAAGTCATATTTGGGGTCAAACCAGGTCCAAGAAGGTTTTGATCACCTATGATGCTTTTCTATGTAATGAAAATGTTAGATCTGGCCCTTACACTtgtatgtaatgtaattaaaaatgtagttaaaaaatggTCTATGGCAGCGATTTTACTCGTGTGCCTGCATATTTCTGTCCCTTTCTTCAGCGCTTCCTGACGCTTGaaactacagtcatatgaaaaagttcaggaacccctcttaattctttggagttttgtttatcattggctgagctttcaaagtagcaacttccttttaatatataacatgtcttatggaaacagtagtatttcagcagtgacttaAAGTTTagtggattaacagaaaatatgcaatatgcatcatgacaaaattagacaggtgcataaatttgggcaccccagcagagatattacatcaatacttagttgagccttgttttgcaaatgtaacagcctatagctgtctcctatagcctttgatgagtgtctggattctacagtatactggtagatcccgatctaactgttgggcacccctgctctagtgTAGTGGCCTTTCCCTAATATTGCATCTGTACCTTTGCTCTGAATAAAGATCCTGTTATTAACCATTGCTGTCTTCTGCAGGTAAATCATGGAAATCCCTTACTCTGGCAACTAAACGCCCCTTTGTGGAAGAAGCTGAGAGGCTGAGGGTGCAGCATATCCAGGACTATCCTGATTACAAATACAGACCCCGCAGGAAGAAGCAGGTGAAGAGGATGAAGAGGGAAGAGGATGGATTCCTTCCCAGTGCAAACTTCCCAGGATCTCAGATAATGGACAACAATGTCATGGTAGGAGAGAACTATAGGATGCAGTATTCTGCGCAGAACCACCAGCAGAACCAACTCCCACCAGCAGGCTACTTTGAGGGCCACAACTCAATTGGATACTATTACAGAGATTACAGTGTACCCAACTACCACATTTCCCAGAACAGCTCTGGCTACGACAGCCCCCCTGCACAAGATGAGTACCAAGCATTGTCTTACAGTTTCAACAGCAGCTATATGCCCTACCAGCAGAATGCTACTACCCCAGTGATGGCTAAACAGATGGCAGTTACCCAGAACATTCCCCAGGAAAGCCCTGAACATGGCATGATGGCTTCTCCACAAATGTACAACAGACAAATGTATGTATCAGAGTGTGCCAAAACCCACCCAATGGCACAGACTGAGCAGCATTTCCCTTCATATCAGTCCCAGAAGATGGTCAGACAGAATTATCTACAGAGCCAGCAAGATGGGCATCTGGAGAGTGACATTGACAAGACTGAGTTCGACCAGTACCTTATGTATGAGCCCAAGGCTGATATGGAGATCATCTATACCATTGACCAGGACAGTGGTGCTTATAGTACAAACCTCCTGCCATCTTTAATCACAGAGGCAAACAATGTCTGCTACTATGACTATTGTGGCGTATAAAGCACTTGCACAGAGAAATAAGCCAATGGACATTAGTATAATTGTGCATTCTGTGCTATGATTATATAACTCTACTGTTAAGTTTATTCACTCTTGTGGATGTGACATGTATCATATTgtatattacatacattattttgTACACGGcagaatttatttacatttaataaatgtactaGGATTTCTATAA

CDS

Gene model

Entrez Gene

394440

100049782

397967

mRNA

RefSeq

Protein

RefSeq

Swiss-Prot

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RefSeq

Swiss-Prot

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RefSeq

Swiss-Prot

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Genomic

X. tropicalis

X. laevis.L

X. laevis.S

Genome Browser

(Click image to open in Genome Browser)

Genomic Synteny

Genomicus PANTHER

Expression

Development Stages

Embryonic Tissues

Adult Tissues

Summary for

More Information

Xenbase Expression Details

In situ images

Single cell data at SPRING

Ensembl

Data Mining

X. tropicalis

X. laevis.L

X. laevis.S

XenMine

sox17b.1

sox17b.1.L

sox17b.1.S

Orthology

Knowledgebases

Entrez Gene

Genetic Phenotypes

Gene Expression

human

OMIM:Gene, GeneCards

SOX17

OMIM

Ensembl, Allen Brain Atlas, Protein Atlas

mouse

rat

zebrafish

chicken

fruit fly

worm

Publications

First

Mixer, a homeobox gene required for endoderm development., Science 1998

Most Recent

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network., Elife 2020

All

View All Papers 14 paper(s) referencing morpholinos

Functional Ontologies

X. tropicalis

X. laevis.L

X. laevis.S

21 terms

4 terms

12 terms

PANTHER

sox17b.1

KEGG Pathways

K04495

KOG

[K] HMG-box transcription factor

Reagents

X. tropicalis

X. laevis.L

X. laevis.S

CRISPRscan Tracks

sox17b.1

Antibodies

Sox17a/b Ab2 , Sox17b Ab1

Morpholinos

sox17b.1 MO1 , sox17b.1/b.2 MO1

ORFs

sox17b.1.S ORF1

Clones

EXRC Horizon Source BioScience

Horizon Source BioScience

Plasmids

Addgene

Symbol legend:

Blast sequence

View sequence

Literature or expression images

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