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Summary Expression Gene Literature (271) GO Terms (26) Nucleotides (87) Proteins (39) Interactants (1048) Wiki
XB-GENEPAGE-484952
Gene Symbol:
akt1

Gene Name:
v-akt murine thymoma viral oncogene homolog 1

Synonyms:
protein kinase B , xAct , pkb , v-akt , v-akt1 , AKT , akt-1 , rac ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
AKT1 is one of several closely related serine/threonine-protein kinases known as the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angioge...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Proteus syndrome [+]

OMIM:
COLORECTAL CANCER; CRC [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-484953 XB-GENE-17332607 XB-GENE-484957
Gene Symbol akt1 akt1.L akt1.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100490038
399170
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine akt1 akt1.L akt1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards AKT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Akt1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Akt1 Ensembl
zebrafish
ZFIN, AGR akt1 ZFIN Ensembl
chicken
GEISHA AKT1 Ensembl
fruit fly
FLYBASE Akt1 Ensembl
worm
Publications
First An amino acid mutation in a potassium channel that prevents inhibition by protein kinase C., Science 1992  
Most Recent The regulation of Akt and FoxO transcription factors during dehydration in the African clawed frog (Xenopus laevis)., Cell Stress Chaperones 2020  
All View All Papers 23 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 0 term 20 terms
PANTHER akt1
KEGG Pathways K04456 K04456
KOG [T] Serine/threonine protein kinase (alt_id KOG:0690)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks akt1
Antibodies Akt1 Ab1 , Akt1 Ab4 , Akt1 Ab2 , Akt1 Ab3 , Akt1 Ab6 , Akt Ab9 Akt1 Ab7 , Akt1 Ab8 , Akt1 Ab6 , Akt Ab9 , Akt1 Ab1 Akt1 Ab1 , Akt1 Ab4 , Akt1 Ab2 , Akt1 Ab3 , Akt1 Ab6 , Akt1 Ab7 , Akt1 Ab8 , Akt Ab9
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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