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Summary Expression Gene Literature (56) GO Terms (19) Nucleotides (55) Proteins (20) Interactants (463) Wiki
XB-GENEPAGE- 484998

Gene Symbol: wt1

Gene Name: Wilms tumor 1

Synonyms: xwt1 , wt-1 , Xwt-1 , wt1-b , wt1-a
Add Xenopus synonyms , Nomenclature history


Gene Function: zinc finger transcription and splicing factor

Protein Function:
Transcription factor required for development of the vascular component of the pronephric kidney, the glomus; may repress tubule-specific gene expression in the portion of the pronephros fated to form ...[+]


Interactants: Loading ...

OMIM Disease Associations: DENYS-DRASH SYNDROME; DDS [+]
1/3
 
Xenbase Gene ID XB-GENE-484999 XB-GENE-6252376 XB-GENE-864792
Gene Symbol wt1 wt1.L wt1.S
Chromosome scaffold_4 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.44768 Xl.246 Xl.172
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 33 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine wt1 wt1.L wt1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards WT1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Wt1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN wt1a wt1b ZFIN Ensembl
chicken
GEISHA WT1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA. [Cytogenet Cell Genet 1995]
Most recent: Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors. [Nat Cell Biol 2016]
View All Papers 18 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 14 terms 17 terms
EC
PANTHER wt1
KEGG Pathways K09234 K09234 K09234
KOG [K] C2H2-type Zn-finger protein
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino wt1 MO1 , wt1 MO2 , wt1 MO3 , wt1 MO4 wt1 MO1 , wt1 MO2 , wt1 MO3 , wt1 MO4 wt1 MO1 , wt1 MO2 , wt1 MO3 , wt1 MO4
Affymetrix 1.0 Str.28694.2.S1_a_at [+] Xl.246.1.S1_at Xl.172.1.S1_s_at
Affymetrix 2.0 Xl2.246.1.S1_at Xl2.172.1.S1_s_at

Symbol legend[+]

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