Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (19) GO Terms (8) Nucleotides (2320) Proteins (35) Interactants (657) Wiki
XB-GENEPAGE-485053
Gene Symbol:
h2az1

Gene Name:
H2A.Z variant histone 1

Synonyms:
H2Az , H2A.z , H2A.Z1 , h2afz ( Add synonyms , Nomenclature history )

Gene Function:
chromatin structure

Protein Function :
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA...[+]


Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-485054 XB-GENE-6256368 XB-GENE-17342536
Gene Symbol h2az1 h2az1.L h2az1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448675
379215
397949
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq RefSeq Swiss-Prot Swiss-Prot Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine h2az1 h2az1.L h2az1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards H2AZ1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR H2az1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR H2az1 Ensembl
zebrafish
ZFIN, AGR h2az2a ZFIN Ensembl
chicken
GEISHA H2AFZ Ensembl
fruit fly
worm
Publications
First H2A.ZI, a new variant histone expressed during Xenopus early development exhibits several distinct features from the core histone H2A., Nucleic Acids Res 1996          
Most Recent Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome., Cell 2019                                  
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 5 terms 0 term
PANTHER h2az1
KEGG Pathways K11251 K11251
KOG [B] Histone 2A (alt_id KOG:1757)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks h2az1
Antibodies h2afz Ab1 h2afz Ab1 h2afz Ab1
Morpholinos h2az1 MO1 , h2az1 MO2 h2az1 MO1 , h2az1 MO2 h2az1 MO1 , h2az1 MO2
ORFs h2afz ORF1 h2afz.L ORF1 LOC397949 ORF2
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556