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Summary Expression Gene Literature (8) GO Terms (22) Nucleotides (111) Proteins (41) Interactants (281) Wiki
XB-GENEPAGE-485072
Gene Symbol:
igfbp5

Gene Name:
insulin like growth factor binding protein 5

Synonyms:
IGFBP-5 , IBP-5 , xIGFBP-5 ( Add synonyms , Nomenclature history )

Gene Function:
growth factor binding

Protein Function :
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs wi...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-485073 XB-GENE-485077 XB-GENE-17343101
Gene Symbol igfbp5 igfbp5.L igfbp5.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 548796
399201
108702907
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine igfbp5 igfbp5.L igfbp5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards IGFBP5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Igfbp5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Igfbp5 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR igfbp5b igfbp5a ZFIN Ensembl
chicken
GEISHA IGFBP5 Ensembl
fruit fly
Publications
First A highly conserved insulin-like growth factor-binding protein (IGFBP-5) is expressed during myoblast differentiation., J Biol Chem 1993  
Most Recent Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor., Dev Biol 2019                                    
All View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 19 terms 6 terms 3 terms
PANTHER igfbp5
KEGG Pathways K23577 K23577
KOG [R] Ca2+-binding proteoglycan Testican
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks igfbp5
Morpholinos igfbp5 MO1 igfbp5 MO1 igfbp5 MO1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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