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Summary Expression Gene Literature (38) GO Terms (29) Nucleotides (72) Proteins (41) Interactants (329) Wiki
XB-GENEPAGE-485175
Gene Symbol:
ret

Gene Name:
ret proto-oncogene

Synonyms:
cret , c-ret , X-ret , xret ( Add synonyms , Nomenclature history )

Gene Function:
tyrosine kinase receptor for GDNF ligand

Protein Function :
Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derive...[+]


InterPro :
WD40 repeat , WD40 repeat dom , F-box-like dom sf , WD40 repeat dom sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
multiple endocrine neoplasia type 2A [+]

OMIM:
CENTRAL HYPOVENTILATION SYNDROME, CONGENITAL; CCHS [+]

External Links:
 
Xenbase Gene ID XB-GENE-485176 XB-GENE-17345822 XB-GENE-864950
Gene Symbol ret ret.L ret.S
Chromosome Chr7 chr7L Scaffold19
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100495902
108696288
373625
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ret ret.L ret.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards RET OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ret MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ret Ensembl
zebrafish
ZFIN, AGR ret ZFIN Ensembl
chicken
GEISHA RET Ensembl
fruit fly
FLYBASE FLYBASE Ret reticulated Ensembl
Publications
First A unique bipartite cysteine-histidine motif defines a subfamily of potential zinc-finger proteins., Nucleic Acids Res 1991    
Most Recent AKT signaling displays multifaceted functions in neural crest development., Dev Biol 2018  
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 27 terms 0 term 9 terms
PANTHER ret
KEGG Pathways K05126 [+] K05126
KOG [T] Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ret
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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