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Summary Expression Gene Literature (72) GO Terms (32) Nucleotides (80) Proteins (39) Interactants (111) Wiki
XB-GENEPAGE-485194
Gene Symbol:
casp1

Gene Name:
caspase 1

Synonyms:
ICE , interleukin-1beta-converting enzyme , xice , caspase 1 , caspase-1 , casp1a , casp1-a , casp1-b ( Add synonyms , Nomenclature history )

Gene Function:
apoptotic cysteine protease

Protein Function :



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-485195 XB-GENE-6252623 XB-GENE-6077552
Gene Symbol casp1 casp1.L casp1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100491605
397719
378669
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine casp1 casp1.L casp1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CASP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Casp1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Casp1 Ensembl
zebrafish
ZFIN, AGR caspb ZFIN Ensembl
chicken
GEISHA CASP1 Ensembl
fruit fly
worm
Publications
First Induction of apoptosis and CPP32 expression by thyroid hormone in a myoblastic cell line derived from tadpole tail., J Biol Chem 1997  
Most Recent Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation., Cancer Cell 2019                                
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 32 terms 3 terms 3 terms
PANTHER casp1
KEGG Pathways K01370 K01370
KOG [D] Caspase, apoptotic cysteine protease
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks casp1
ORFs casp1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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