|
XB-GENEPAGE-485219
Gene Symbol:
otx2
Gene Name: orthodenticle homeobox 2
Synonyms:
Xotx2
,
otx-2
,
Xotx-2
,
otxA
,
otx2-a
,
otx2-b
( Gene Function: homeodomain transcription factor Protein Function
![]()
May play a central role in the initial events of axis formation and in particular in specifying anterior head regions and their spatial relationship with trunk structures. Activates the head organizer ...[+]
Interactants:
Loading ...
Diseases: Disease Ontology:
septooptic dysplasia
OMIM:
MICROPHTHALMIA, SYNDROMIC 5; MCOPS5
External Links:
|
|
Xenbase Gene ID | XB-GENE-485220 | XB-GENE-485224 | XB-GENE-6254039 | |||||
Gene Symbol | otx2 | otx2.L | otx2.S | Chromosome | Chr8 | chr8L | chr8S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
![]() |
Version 9.1
![]() |
Version 9.1
![]() |
|||||
CDS |
Gene model
![]() |
Gene model
![]() |
Gene model
![]() |
|||||
Entrez Gene |
548931
|
432013
|
399342
|
|||||
mRNA |
RefSeq
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
|||||
Protein
![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
|||||
Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
|
||||||||
Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
|
|||||||
More Information |
|
|||||||
Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
|||||||
Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | otx2 | otx2.L | otx2.S | |||||
Phenotype | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Smith Morpholino Screen | tgas114a06 | |||||||
Orthology |
|
|||||||
human |
|
|||||||
mouse |
|
|||||||
rat |
|
|||||||
zebrafish |
|
|||||||
chicken |
|
|||||||
fruit fly |
|
|||||||
worm |
|
|||||||
Publications | ||||||||
First |
Neural induction by the secreted polypeptide noggin., Science 1993 |
|||||||
Most Recent |
Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., EMBO J 2021 ![]() |
|||||||
All | View All Papers 137 paper(s) referencing morpholinos 14 paper(s) referencing OMIMs 26 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 11 terms | 6 terms | 7 terms | |||||
PANTHER | otx2 | |||||||
KEGG Pathways | K18490 | K18490 | K18490 | |||||
KOG |
[K] Homeobox transcription factor
|
|||||||
Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | otx2 | |||||||
Antibodies | Otx2 Ab1 , Otx2 Ab2 , Otx2 Ab3 , Otx2 Ab4 | Otx2 Ab1 , Otx2 Ab2 , Otx2 Ab3 , Otx2 Ab4 | Otx2 Ab1 , Otx2 Ab2 , Otx2 Ab3 , Otx2 Ab4 | |||||
Morpholinos (on-target & off-target) | otx2 MO3 , otx2 MO1 , otx2 MO2 | otx2 MO3 , otx2 MO1 , otx2 MO2 | otx2 MO3 , otx2 MO1 , otx2 MO2 | |||||
ORFs | otx2 ORF1 | otx2.L ORF1 | otx2.S ORF1 | |||||
Clones | EXRC Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



