Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (166) GO Terms (11) Nucleotides (35) Proteins (15) Interactants (771) Wiki
XB-GENEPAGE- 485279

Gene Symbol: wnt1

Gene Name: Wnt family member 1

Synonyms: Xwnt1 , Xwnt-1 , Xint-1 , int1 , int-1 , wnt-1
Add Xenopus synonyms , Nomenclature history


Gene Function: secreted growth factor/developmental regulator

Protein Function:
Ligand for members of the frizzled family of seven transmembrane receptors.


Interactants: YYY

OMIM Disease Associations: BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 16; BMND16 [+]
 
Xenbase Gene ID XB-GENE-485280 XB-GENE-865073 XB-GENE-17343679
Gene Symbol wnt1 wnt1.L wnt1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Xl.29 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 17 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine wnt1 wnt1.L wnt1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards WNT1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Wnt1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN wnt1 ZFIN Ensembl
chicken
GEISHA WNT1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Isolation of the Xenopus homolog of int-1/wingless and expression during neurula stages of early development. [Nucleic Acids Res 1989]
Most recent: Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. [Dev Cell 2017]
View All Papers 29 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 6 terms 4 terms
EC
PANTHER wnt1
KEGG Pathways K03209 K03209 K03209
KOG [T] Wnt family of developmental regulators
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 2 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Antibody Wnt1 Ab1 Wnt1 Ab1
Morpholino wnt1 MO1 wnt1 MO1 wnt1 MO1
Affymetrix 1.0 StrEns.3421.1.S1_at Xl.29.1.S1_at [+]
Affymetrix 2.0 Xl2.29.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556