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Summary Expression Gene Literature (182) GO Terms (17) Nucleotides (50) Proteins (29) Interactants (1012) Wiki
XB-GENEPAGE-485279
Gene Symbol:
wnt1

Gene Name:
Wnt family member 1

Synonyms:
Xwnt1 , Xwnt-1 , Xint-1 , int1 , int-1 , wnt-1 ( Add synonyms , Nomenclature history )

Gene Function:
secreted growth factor/developmental regulator

Protein Function :
Ligand for members of the frizzled family of seven transmembrane receptors.


InterPro :
Wnt1 , Wnt , Wnt CS , Cys-rich flank reg C [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
osteogenesis imperfecta type 15

OMIM:
BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 16; BMND16 [+]

External Links:
 
Xenbase Gene ID XB-GENE-485280 XB-GENE-865073 XB-GENE-17343679
Gene Symbol wnt1 wnt1.L wnt1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100491444
373578
108709815
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot NCBI Protein
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine wnt1 wnt1.L wnt1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards WNT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Wnt1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Wnt1 Ensembl
zebrafish
ZFIN, AGR wnt1 ZFIN Ensembl
chicken
GEISHA WNT1 Ensembl
fruit fly
worm
Publications
First Isolation of the Xenopus homolog of int-1/wingless and expression during neurula stages of early development., Nucleic Acids Res 1989  
Most Recent Mechanistic insights from the LHX1-driven molecular network in building the embryonic head., Dev Growth Differ 2019  
All View All Papers 31 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 6 terms 5 terms
PANTHER wnt1
KEGG Pathways K03209 K03209 K03209
KOG [T] Wnt family of developmental regulators
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks wnt1
Antibodies Wnt1 Ab1 , Wnt1 Ab2 Wnt1 Ab1 , Wnt1 Ab2 Wnt1 Ab2
Morpholinos wnt1 MO1 wnt1 MO1 wnt1 MO1
Clones Horizon Horizon Source BioScience Horizon

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