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Summary Expression Gene Literature (30) GO Terms (8) Nucleotides (85) Proteins (27) Interactants (1003) Wiki
XB-GENEPAGE-485440

Gene Symbol: pitx1

Gene Name: paired like homeodomain 1

Synonyms: X-PITX-1 , xPitx1 , Xpitx-1 ( Add synonyms , Nomenclature history )

Gene Function: homeodomain transcription factor

Protein Function :
Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies an...[+]

Interactants: Loading ...
Disease Ontology: clubfoot

OMIM Diseases: LIEBENBERG SYNDROME; LBNBG [+]

GEO Series : GSE111454.
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Xenbase Gene ID XB-GENE-485441 XB-GENE-485445 XB-GENE-17330607
Gene Symbol pitx1 pitx1.L pitx1.S
Chromosome Chr03 chr3L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine pitx1 pitx1.L pitx1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PITX1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Pitx1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR pitx1 ZFIN Ensembl
chicken
GEISHA PITX1 Ensembl
fruit fly
worm
WORMBASE
Publications
First The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping., Development 1999              
Most Recent Structure, development, and functional morphology of the cement gland of the giant danio, Devario malabaricus., Dev Dyn 2019  
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 4 terms 0 term
PANTHER pitx1
KEGG Pathways K09356 K09356
KOG [K] Transcription factor PTX1, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino pitx1 MO1 , pitx1 MO2 pitx1 MO1 , pitx1 MO2 pitx1 MO1 , pitx1 MO2
ORF pitx1 ORF1
Affymetrix 1.0 Str.24178.1.S1_at Xl.522.1.S1_at
Affymetrix 2.0 Xl2.522.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.11.4


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