cdk7 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (25)

Nucleotides (110)

Interactants (22)

XB-GENEPAGE-485506

Gene Symbol: cdk7 Gene Name: cyclin-dependent kinase 7 Synonyms: p40MO15, MO15, stk1 Add Xenopus synonyms Gene Function: Cdk activating kinase Interactants: cdk1(18) , pold1(14) , cdk2(11) , mnat1(4) , ccnb1.2(3) , gtf2h4(3) , anxa2(2) View All

XB-GENE-485507

XB-GENE-485511

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001017219\|Xenopus (Silurana) tropicalis cyclin-dependent kinase 7 (cdk7), mRNA TTAAATGGCGATGTGACAGTGACCTGTGGGAAAGGGTTGCGCGGAGAATGGAGGGGATAATGGCGAGAGGGGTGGATGTGCGCTCCCGTTCCAAGCAGTATGAGAAGCTGGAGTTCCTGGGGGAAGGCCAGTTTGCCACAGTTTATAAAGCAAGAGACAAGAATACAGATAGAATTGTGGCCATTAAAAAGATTAAACTGGGACATAGAGCAGAGGCTAAAGATGGTATAAACAGAACAGCACTCAGAGAGATAAAGCTGCTGCAGGAGTTAAGCCATCCTAATATCATTGGCCTTCTGGATGCTTTTGGACACAAATCAAACATAAGCCTGGTGTTTGATTTTATGGAGACAGATCTTGAGGTTATAATAAAAGATACCAGCTTGGTATTAACTCCAGCTCATATTAAATCATACATGCTGATGACTCTGCAGGGCTTGGAATACTTACACCACCTCTGGATCCTGCACAGAGACTTGAAGCCAAATAATTTGCTGCTGGATGAAAATGGGGTCCTTAAACTTGCTGATTTTGGTCTTGCAAAGTCATTTGGGAGTCCAAACAGAATATATACTCATCAAGTAGTAACAAGGTGGTACCGATCTCCTGAGTTGCTGTTTGGTGCTAGAATGTACGGTGTGGGAGTAGACATGTGGGCAGTTGGCTGCATCTTAGCAGAGCTGCTACTTCGGGTGCCCTTTTTGCCTGGGGACTCTGATCTAGACCAACTTACAAGAATATTTGAAACTTTGGGAACACCAACAGAAGAGCAATGGCCGGGCATGTCCAGCCTTCCAGACTACGTTGCCTTTAAAAGTTTTCCAGGGACACCGCTCCACCATATTTTTATTGCAGCTGGTGATGATCTTCTTGAACTTTTGCAAGGCTTATTTACCTTTAATCCATGTGCACGATGCACAGCATCCCAGGCACTCAGAAAAAGGTATTTTAGCAACAGACCGGCGCCAACCCCAGGAAGCCTTTTGCCAAGACCAAATTGTTCTGTAGAAGCGTTAAAGGAGCAGCAAAATCTCAATCTAGGCATAAAGAGAAAGCGGACAGAAGGCATGGATCAAAAAGACATTGCTAAGAAGTTGAATTTTTGAATGCAGACCATGTGCACCACATGCATAACATGAAAGAAAACTGCTGCTATAAACTAGATGTCAGAGAGCGGTCCATGAAAAACTTGTAATATATGTAAATACTGAGTTACGTGGTTGGTAACAGATTTAGTCATTAAAATAATAATTTCTAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001090892\|Xenopus laevis cyclin-dependent kinase 7 (cdk7), mRNA GCTGCAGGGAGAATGGAAGGTATAGCGGCGAGAGGGGTGGACGTGCGGTCCCGTGCCAAGCAGTATGAGAAGCTGGATTTCCTAGGCGAAGGGCAGTTTGCCACTGTTTATAAAGCCCGAGACAAGAATACTGATAGAATTGTGGCCATTAAAAAGATTAAACTGGGGCATAGAGCAGAAGCTAATGATGGGATAAACAGAACAGCGCTGAGAGAGATAAAGCTACTACAGGAGTTAAGCCATCCTAATATCATTGGGCTACTGGATGCTTTTGGACACAAATCCAACATAAGCCTGGTGTTTGATTTTATGGAGACGGATCTTGAGGTCATAATAAAAGATACCAGCTTGGTATTAACTCCAGCTCATATTAAATCATACATGCTGATGACTCTTCAAGGCTTGGAATACTTACACCATCTCTGGATCCTCCATAGAGATTTAAAGCCGAATAATTTGTTGCTGGATGAAAATGGGGTCCTTAAACTTGCTGATTTTGGTCTTGCAAAGTCATTTGGGAGTCCAAACAGAATATATACTCATCAAGTGGTAACAAGGTGGTACCGATCTCCTGAGTTGCTGTTTGGTGCTAGAATGTATGGTGTGGGAGTTGACATGTGGGCAGTTGGCTGCATCTTAGCTGAGCTGCTACTTCGGGTGCCTTTTTTACCTGGGGATTCTGATCTAGACCAGCTAACGAGAATATTTGAAACTTTGGGAACACCAACTGAAGAGCAGTGGCCGGGCATGTCCAGCCTTCCAGACTATGTTGCCTTTAAAAGTTTTCCAGGGACACCACTGCACCTCATTTTTATTGCTGCTGGCGATGATCTTCTTGAACTCCTGCAAGGTTTATTTACCTTTAATCCGTGTGCAAGATGCACAGCATCCCAGGCACTTCGAAAAAGGTATTTTAGCAACAGACCGGCACCAACCCCAGGAAACTTGTTGCCAAGACCCAATTGTTCTATAGAAGCATTAAAGGAGCAGCAAAATCTCAACCTGGGAATAAAGAGAAAGCGGACAGAAGGCATGGATCAAAAAGACATTGCTAAGAAGTTGAGTTTTTGACTCCAGACAATGTAGACCATACGCCAAGCCTGAGAGAAAACTGCTGCTATAAACAGAGACGTCAGAGACCGGTCCATGAAATGAACTAAAACTTGTAATATATGTAAATACTGAGTTGCGTGATCCGTAACAGAACTAGTCATTAAAATAATACTTTCTAAAATAAGGGTTTTGTTTTGACAATTTGGTTTATTTAGGACTGTGTGAAGGCACATTCTCCCTAACCTGCAACTGTACTTGTAGAACATTTCTCAACTGATCGGAATAGATGCACAAAGGTTTAAAGGAGATGGAGACTTAAAATACACTTTGTTAGTAACATGGTGAAGAGCAGCTTTTTTCCTGTGTTTTTATATAAAATCTAATGAAGCTACAGACTTCATCGGTGGGTTGTACTAGTTAGGTATGGCCAGCCATTTCCATAACAGGGATAGGTCAGCTGATTTTCTTATCGCCTATACAGATCTATCCAGTCTACACTATCCCCCCTAGACTATGATAATTTAGGTATTCCCTTCCAATAAAAACAATTGTGCAGTGAACATGGAGGGTATAGTAGCCCTTTATTCATGCAGGAATAGCCTGTCTGTCGACGTCAATAATCCAAAATACTGATGGTTTTCTGTAGTAGCAGAATCTTACATCTGCTGAAGAGAGCTTTTAAATGTAAAAGCGGTATATACAGGTATGGGACCTGTTATCCAGAATGCTCGGCACCTGGGGTTTTCAGGATAACTGATCTTTCTGTAATTTGGATTTTTTTTTCCCACTTGAAGTGAGAGCTGCCATCATAATTGTTACTCAGAACAGGCTTTTTTCCAAATTCCTTTGTACACTCATACTATATATTTATAAACTGTAGATGAGATTGCACTCTCTTTACATTTACATTGCACTCTTTACTTTACGGGGCACATTTACCTAGGGTCGAATATCGAGGGTTAATTAACCCTCGATATTCGACCGCCGAAGTAGAATCCTTTGAAGTCGAAGGATTTACCGCTATTCCTACGATCGAAGGAATAATCCTTCGATCGAACGATTAAATCCTTCCAATCGAACGATTCGAAGGATTTCAGTCCATCGATAGAAGGATATTCCTTCGATCAGGAAGTTGTTAGGATGCCTATGGGGACCTTCCCCATAGGCTAACATTGACCTCGGTAGGTTTTAGGTGGCGAACTAGGGGGTCGAAGAATTTTTTAAAGAGACAGTACTTCGACTATCGAATAGTCGAGCGATTTTTATTTTGAATCGTTCGATTTGTGGTCGAAGTAACCCATTCGATGGTCGAAAGTAGCCATATTCGACCATTCGAAATTCAAACTTTTTTTCCTCTATTCCTTCACTCAAACTAAGTAAATGGGCCCCTACATTTATCGTTTACAGATTCTTTTATGATTTTATTTACATTTTTATTAATCTGTGTGCACACAGAATAAGCTGTGCCCCCTTGCTTTTTCCAGGCTCTTTTAAGGAGCAGTTGTTCTTAAAGGAATAGTTCACTTGCAGGACCGTGCACATGCTCGGTGTGGTCTGGGCGGCTTGGGGATCGCCATGAATGATCAAAACAGCACAGGTCGGGTAGTGTCTGCCAGTGCAGTCTGCATGTTCTGGTTGTTGATCGGTCTTGCTGTGTCGGCCTCTGTCAGATATTATTTGACTTGTGCTATTTTTATGATTTGTGATGATCCCTGGGCCGCTCAGGCCACACTGAGCATGTGCACAGTCTTGGTCTTGCAAAGATGTTTAACAAAGTTACAAGATGGTGACCCCCTATGGCCAACTTTGAAAGCATAAATTATTTGTTTGATTAGGCTTGTGGTGCAGTAAGTTTGTTTAGTATAACAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001017219\|cyclin-dependent kinase 7 [Xenopus (Silurana) tropicalis] MEGIMARGVDVRSRSKQYEKLEFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDTSLVLTPAHIKSYMLMTLQGLEYLHHLWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRIYTHQVVTRWYRSPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPGMSSLPDYVAFKSFPGTPLHHIFIAAGDDLLELLQGLFTFNPCARCTASQALRKRYFSNRPAPTPGSLLPRPNCSVEALKEQQNLNLGIKRKRTEGMDQKDIAKKLNF	Refseq >NP_001084361\|cyclin-dependent kinase 7 [Xenopus laevis] MEGIAARGVDVRSRAKQYEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDTSLVLTPAHIKSYMLMTLQGLEYLHHLWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRIYTHQVVTRWYRSPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPGMSSLPDYVAFKSFPGTPLHLIFIAAGDDLLELLQGLFTFNPCARCTASQALRKRYFSNRPAPTPGNLLPRPNCSIEALKEQQNLNLGIKRKRTEGMDQKDIAKKLSF UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.10484 [+] Str.61014	Xl.15107
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CDK7
mouse		MGI	Cdk7	All(6) Gene Trapped(3) Targeted, other(2)
zebrafish		ZFIN	cdk7

Publications
First:		p40MO15, a cdc2-related protein kinase involved in negative regulation of meiotic maturation of Xenopus oocytes. [EMBO J 1990]
Most recent:		Comparison of Cak1p-like cyclin-dependent kinase-activating kinases. [J Biol Chem 2002]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding cAMP-dependent protein kinase activity cAMP-dependent protein kinase regulator activity More[+] protein kinase CK2 activity protein kinase CK2 regulator activity protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity
Biological:		protein amino acid phosphorylation
Cellular Component:		cAMP-dependent protein kinase complex protein kinase CK2 complex
EC:		now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
KOG:		[DKL] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7

Reagents		tropicalis	laevis
Clones			EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.10484.1.S1_at [+] Str.35459.1.S1_at	Xl.1768.1.S1_at
Affymetrix 2.0			Xl2.1768.1.S1_at

Symbol legend[+]