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Summary Expression Gene Literature (29) GO Terms (11) Nucleotides (112) Proteins (26) Interactants (211) Wiki
XB-GENEPAGE- 485506

Gene Symbol: cdk7

Gene Name: cyclin-dependent kinase 7

Synonyms: p40MO15 , MO15 , stk1
Add Xenopus synonyms , Nomenclature history


Gene Function: Cdk activating kinase

Protein Function:
Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. Cyclin-dependent kinases (CDKs) are activated by the binding to a cyclin and mediate the prog...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-485507 XB-GENE-485511 XB-GENE-17344877
Gene Symbol cdk7 cdk7.L cdk7.S
Chromosome Chr01 chr1L
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.10484 [+] Xl.15107
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 1 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine cdk7 cdk7.L cdk7.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CDK7 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Cdk7 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN cdk7 ZFIN Ensembl
chicken
GEISHA CDK7 Ensembl
fruit fly
FLYBASE Cdk7 Ensembl
worm
WORMBASE
Publications
First: p40MO15, a cdc2-related protein kinase involved in negative regulation of meiotic maturation of Xenopus oocytes. [EMBO J 1990]
Most recent: Genes coding for cyclin-dependent kinase inhibitors are fragile in Xenopus. [Dev Biol 2017]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 6 terms 0 term
EC now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
PANTHER cdk7
KEGG Pathways K02202 K02202
KOG [DKL] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF cdk7 ORF1
Affymetrix 1.0 Str.10484.1.S1_at [+] Xl.1768.1.S1_at
Affymetrix 2.0 Xl2.1768.1.S1_at

Symbol legend[+]

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