Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (81) GO Terms (79) Nucleotides (77) Proteins (38) Interactants (935) Wiki
XB-GENEPAGE-485516
Gene Symbol:
lef1

Gene Name:
lymphoid enhancer binding factor 1

Synonyms:
xlef-1 , lef-1 , xlef1 ( Add synonyms , Nomenclature history )

Gene Function:
HMG box transcription factor, wnt signaling

Protein Function :


InterPro :
LEF1 , HMG box dom sf , HMG box dom , Catenin binding dom sf [+]

Interactants:
Loading ...

Diseases: 


OMIM:
LYMPHOID ENHANCER-BINDING FACTOR 1; LEF1

External Links:
 
Xenbase Gene ID XB-GENE-485517 XB-GENE-865531 XB-GENE-17336734
Gene Symbol lef1 lef1.L lef1.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100493178
398238
779101
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lef1 lef1.L lef1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, LEF1 Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lef1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lef1 Ensembl
zebrafish
ZFIN, AGR lef1 ZFIN Ensembl
chicken
GEISHA LEF1 Ensembl
fruit fly
worm
Publications
First Functional interaction of beta-catenin with the transcription factor LEF-1., Nature 1996  
Most Recent Model systems for regeneration: Xenopus., Development 2020            
All View All Papers 14 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 79 terms 6 terms 6 terms
PANTHER lef1
KEGG Pathways K04492 [+] K04492 K04492
KOG [K] Transcription factor TCF-4
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lef1
Morpholinos (on-target & off-target) lef1 MO5 , lef1 MO1 , lef1 MO2 lef1 MO1 , lef1 MO2 lef1 MO1 , lef1 MO2
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info