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Summary Expression Gene Literature (82) GO Terms (5) Nucleotides (51) Proteins (15) Interactants (535) Wiki
XB-GENEPAGE- 485516

Gene Symbol: lef1

Gene Name: lymphoid enhancer binding factor 1

Synonyms: xlef-1 , lef-1 , xlef1
Add Xenopus synonyms , Nomenclature history

Gene Function: HMG box transcription factor, wnt signaling

Protein Function:


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-485517 XB-GENE-865531 XB-GENE-17336734
Gene Symbol lef1 lef1.L lef1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.10421 Xl.85523 Xl.58036
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 9 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine lef1 lef1.L lef1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LEF1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Lef1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN lef1 ZFIN Ensembl
chicken
GEISHA LEF1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. [Cell 1996]
Most recent: High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis. [Dev Biol 2017]
View All Papers 14 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 5 terms 0 term
EC
PANTHER lef1
KEGG Pathways K04492
KOG [K] Transcription factor TCF-4
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 4 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino lef1 MO1 , lef1 MO2 , lef1 MO3 , lef1 MO4 , lef1 MO5 lef1 MO1 , lef1 MO2 , lef1 MO3 , lef1 MO4 , lef1 MO5 lef1 MO1 , lef1 MO2 , lef1 MO3 , lef1 MO4 , lef1 MO5
Affymetrix 1.0 Str.10421.2.A1_at [+] Xl.410.1.S1_at
Affymetrix 2.0 Xl2.410.1.S1_at

Symbol legend[+]

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