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Summary Expression Gene Literature (27) Nucleotides (72) Proteins (22) Interactants (350) Wiki
XB-GENEPAGE- 485651

Gene Symbol: hnf1b

Gene Name: HNF1 homeobox B

Synonyms: vhnf1 , hnf1beta , hnf-1beta , tcf2 , hnf1-beta , lfb3
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Interactants: hnf1a (8) , lhx1 (8) , pax2 (8) , pax8 (8) , odc1 (6) , slc12a1 (6) , gata4 (5) View All

OMIM Disease Associations: DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]
1/3
 
Xenbase Gene ID XB-GENE-485652 XB-GENE-485656 XB-GENE-17330995
Gene Symbol hnf1b hnf1b.L hnf1b.S
Chromosome: Chr02 chr2L chr2S
Molecules tropicalis laevis .L laevis.S
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 GBrowse 7.2 GBrowse 6.0 GBrowse 9.1
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq
Genomic tropicalis laevis .L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis .L laevis.S
Ensembl Ensembl
UniGene Str.27039 Xl.65135 Xl.12667 [+]
RNA-seq profile: Owens, Blitz et al. 2016 hnf1b
Images 55 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis .L laevis.S
XenMine hnf1b hnf1b.L hnf1b.S
Phenotype tropicalis laevis .L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HNF1B OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Hnf1b MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN hnf1bb hnf1ba ZFIN Ensembl
chicken
GEISHA HNF1B Ensembl
fruit fly
worm
WORMBASE
Publications
First: Cloning and developmental expression of LFB3/HNF1 beta transcription factor in Xenopus laevis. [Mech Dev 1994]
Most recent: Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors. [Nat Cell Biol 2016]
View All Papers 6 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding   obsolete transcription activator activity   transcription factor activity, sequence-specific DNA binding  
      Biological: positive regulation of transcription   regulation of transcription, DNA-templated  
      Cellular Component: nucleus  
EC:
PANTHER: hnf1b
KOG: [R] FOG: Zn-finger
Reagents tropicalis laevis .L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
ORF hnf1b ORF1
Affymetrix 1.0 Str.27039.1.S1_at Xl.24918.1.A1_s_at [+]
Affymetrix 2.0 Xl2.15455.1.S1_at [+]

Symbol legend[+]

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