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Summary Expression Gene Literature (286) GO Terms (15) Nucleotides (96) Proteins (39) Interactants (873) Wiki
XB-GENEPAGE-485651
Gene Symbol:
hnf1b

Gene Name:
HNF1 homeobox B

Synonyms:
vhnf1 , hnf1beta , hnf-1beta , tcf2 , hnf1-beta , lfb3 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.


InterPro :
Chromo domain , Chromo-like dom sf , Zinc finger PHD-type CS , P-loop NTPase [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
nonpapillary renal cell carcinoma [+]

OMIM:
TYPE 2 DIABETES MELLITUS; T2D [+]

External Links:
1/6
 
Xenbase Gene ID XB-GENE-485652 XB-GENE-485656 XB-GENE-17330995
Gene Symbol hnf1b hnf1b.L hnf1b.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 733490
398842
380377
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hnf1b hnf1b.L hnf1b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HNF1B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hnf1b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hnf1b Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR hnf1bb hnf1ba ZFIN Ensembl
chicken
GEISHA HNF1B Ensembl
fruit fly
worm
Publications
First Cloning and developmental expression of LFB3/HNF1 beta transcription factor in Xenopus laevis., Mech Dev 1994          
Most Recent Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network., Elife 2020                        
All View All Papers 9 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 7 terms 12 terms
PANTHER hnf1b
KEGG Pathways K08034 K08034 K08034
KOG [R] FOG: Zn-finger
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hnf1b
Morpholinos hnf1b MO1 hnf1b MO1 hnf1b MO1
ORFs hnf1b.L ORF1 hnf1b.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list