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Summary Expression Gene Literature (23) Nucleotides (70) Proteins (22) Interactants (241) Wiki
XB-GENEPAGE-485651

Gene Symbol: hnf1b

Gene Name: HNF1 homeobox B

Synonyms: vhnf1, hnf1beta, hnf-1beta, tcf2, hnf1-beta, lfb3 Add Xenopus synonyms

Gene Function: homeodomain transcription factor

Interactants: hnf1a(7) , lhx1(7) , odc1(6) , pax2(6) , pax8(6) , slc12a1(6) , slc4a4(5) View All

Disease Associations: DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]
1/2
 
Xenbase Gene ID XB-GENE-485652 XB-GENE-485656
Current JGI Annotation hnf1b hnf1b.L
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene Str.27039 Xl.65135 [+]
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 44 expression image(s) for tropicalis and laevis
Phenotype tropicalis laevis
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC HNF1B OMIM:125853 OMIM:176807 OMIM:137920 OMIM:144700 OMIM:611955
mouse
MGI Hnf1b All available mutants
zebrafish
ZFIN ZFIN hnf1bb hnf1ba All
chicken
Publications
First: Cloning and developmental expression of LFB3/HNF1 beta transcription factor in Xenopus laevis. [Mech Dev 1994]
Most recent: Pax8 and Pax2 are specifically required at different steps of Xenopus pronephros development. [Dev Biol 2015]
View All Papers 6 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding
transcription activator activity
transcription factor activity
      Biological: positive regulation of transcription
regulation of transcription, DNA-dependent
      Cellular Component: nucleus
EC:
KOG: [R] FOG: Zn-finger
Reagents tropicalis laevis
CRISPR / TALEN CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
ORF hnf1b ORF1
Affymetrix 1.0 Str.27039.1.S1_at Xl.24918.1.A1_s_at [+]
Affymetrix 2.0 Xl2.15455.1.S1_at [+]

Symbol legend[+]

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