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Summary Expression Gene Literature (21) Nucleotides (70) Proteins (22) Interactants (212) Wiki
XB-GENEPAGE-485651

Gene Symbol: hnf1b

Gene Name: HNF1 homeobox B

Synonyms: vhnf1, hnf1beta, hnf-1beta, tcf2, hnf1-beta, lfb3 Add Xenopus synonyms

Gene Function: homeodomain transcription factor

Interactants: hnf1a(6) , lhx1(6) , pax2(5) , pax8(5) , slc12a1(5) , foxa2(4) , hnf4a(4) View All

Disease Associations: DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]
1/2
 
  XB-GENE-485652 XB-GENE-485656
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
tropicalis 4.1 synteny
Expression tropicalis laevis
UniGene Str.27039 Xl.65135 [+]
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 19 expression image(s) for tropicalis and laevis
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC HNF1B OMIM:125853 OMIM:176807 OMIM:137920 OMIM:144700 OMIM:611955
mouse
MGI Hnf1b All
zebrafish
ZFIN ZFIN hnf1bb hnf1ba All
chicken
Publications
First: Cloning and developmental expression of LFB3/HNF1 beta transcription factor in Xenopus laevis. [Mech Dev 1994]
Most recent: Recessive mutations in PCBD1 cause a new type of early-onset diabetes. [Diabetes 2014]
View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding
transcription activator activity
transcription factor activity
      Biological: positive regulation of transcription
regulation of transcription, DNA-dependent
      Cellular Component: nucleus
EC:
KOG: [R] FOG: Zn-finger
Reagents tropicalis laevis
CRISPR / TALEN Design E-CRISP / Other tools
Design E-CRISP / Other tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody
Morpholino
Affymetrix 1.0 Str.27039.1.S1_at Xl.24918.1.A1_s_at [+]
Affymetrix 2.0 Xl2.15455.1.S1_at [+]

Symbol legend[+]

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