hnf1b Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (17)

Nucleotides (68)

Interactants (108)

XB-GENEPAGE-485651

Gene Symbol: hnf1b Gene Name: HNF1 homeobox B Synonyms: vhnf1, hnf1beta, hnf-1beta, tcf2, hnf1-beta, lfb3 Add Xenopus synonyms Gene Function: homeodomain transcription factor Interactants: lhx1(5) , pax2(5) , pax8(5) , hnf1a(4) , odc1(4) , slc12a1(4) , slc4a4(4) View All	1/2

XB-GENE-485652

XB-GENE-485656

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >CR760425\|Xenopus tropicalis finished cDNA, clone TNeu141k07 ACCGCCAGTGAGTACACTGACCAATATTCACAACCTGTCCCAGTCTGTTCATCACAATCCTCAGCAATCTCAAAACCTTATCATGGCACCAATCTCCGGAGTGATGGCAATTACGCAGAATTTAAACACCTCTCAGGCGCAAAGTGTTCCTGTTATCAACAGTGTTGCAGGGAGCCTGGCAGCTTTACAATCTGTACAGTTTTCACAGCAACTACATAGTCCACATCAGCAGCAACTCATGCAACAGTCCCCTGGGCACATGGCACAACAGCCATTTATGGCCACTGTCACTCAGCTTCAGAATTCACACATGTATGCACACAAGCAAGAGCCTCCCCAGTATTCCCACACATCTCGTTTTCCTTCAGCCATGGTTGTCACAGATACTAGCAGCATCAGCACATTATCAAACATGTCTTCCAGTAAACAGTGTCCTTTGCAAGCATGGTGATGAACAATATTATCCAAGTATTTCATATTTTTGCTCCTGAAGTCTTCTGCTGCTTGTTGCTGCTCACAGGAATAATACCAAAAGGCCCTTAATGTTGTACCTCTAATGTTGGATGTACCACATGTGCTTAAGTACACTTGCATTGCAGTCCCTTTTGCAGTATTTCCAGGAAGAGCATTCAAGGCCAAAGTATTTTCCTTAAATAAACAACTGGGAACAGAACAAATTTTTGTGGGAAAACCACAAAGGAAGACTAAAGATAAACGGACAGCTAAAAACTGAATGTAGAAATCTATGCATACATTGAACTGAGCCAATGTAAATATCTTTTTATTAAGACATGAAAACAAAATATTTCTTTATAAGAAGGTAATTTGTTGAATAATTGTAAAAATGTAGAAAAGTGCAATTTTTTGTACATATTATAAAAAAAATAATGCTTGGGCAAAAAAAAAAAAAAAAAA	Refseq >NM_001089811\|Xenopus laevis HNF1 homeobox B (hnf1b), mRNA GCAGACTCTCTGCAGGGAGATTCTCTGTAAGCGCTAGAGGGACAGGTGCTCTGGGACAAGGGGATTCCAGATCCCTTGATTTTTTGTTTTACTCCCCTATCCCTTTTCCTTCTTTTCTTCCTTCTAAAATGGTGTCCAAGCTATCGCCTTTGCAGCAGGAACTCCTCAATGCTCTCCTGAACTCTGGAGTAACCAAAGAGGATTTGATCCAGGCCTTGGAAGATATGATCCCCAGCCCAAGCTTTGGGGTAAAGCTGGAGAACTTGCACATGTCCCCGGAACATGAGGTTGACAGTAAGCCCGTATTCCACACTCTTACTAATGGCCACCACCACAAGGGCAAACTCTCCGGGGATGAGGGCTCAGAGGATGGAGACGACTTTGATACCCCTCCAATCCTTAAAGAACTGCAGTCCCTTAATACGGAGGAGGCAGCTGAGCAAAGGGCAGAAGTGGACAGGATGCTAAGCGAGGATTCATGGAGGGCTGCAAAAATGATAAAGGGTTACATGCAACAACACAACATTCCTCAGAGAGAAGTGGTGGATATCACTGGCTTAAACCAGTCCCATCTCTCCCAACACTTAAACAAAGGAACACCAATGAAGACCCAAAAACGTGCTGCATTGTACACTTGGTATGTGAGGAAACAAAGGGAGATATTAAGACAATTCAACCAGACAGTCCAGGGTTCTGAAAATATCACAGACAAAAGCAGTCAGGATCAGCTGCTGTTTCTCTTTCCAGAGTTTAATCAGCAAAATCAAGTTCAAGGACAGCCTGATGATACCTGCTCAGAGCCTTCCAACAAGAAGATGAGACGAAATCGTTTCAAATGGGGGCCTGCATCACAGCATATTCTTTATCAAGCCTATGAAAGGCAAAAGAATCCCAGCAAAGAAGAAAGAGAAGCTTTAGTGGAAGAATGTAACAGAGCGGAATGTCTTCAGCGTGGTGTATCTCCATCTAAAGCTCATGGCCTTGGATCAAATTTGGTAACAGAAGTCCGTGTTTATAACTGGTTTGCAAACAGAAGGAAAGAAGAGGCTTTTCGACAAAAACTGGCTATGGATGCCTATAGTACTGGCCCATCACACCCCCACAACTTGAATTCTCTACTATCACATGGATCACCACACCATACACAACCAAGCACTTCTCCACCAAGTAAACTGCAAGGGCTGAGATATAGTCAACAAGGAAACAATGAAGTCACTTCATCATCAACTATCAGTCACCATGGCAACAATGCTATGGTGACCAGCCAATCTATTTTACAGCAAGTTTCTCCAGTGTGCTTGGATCACAGCCACAGCATGCTTTCACCTGATGGCAAACTGATATCTGTTTCTGGAGGAGGATTACCGCCAGTGAGTACGCTGACAAATATTCACAACCTATCCCAGTCTGTTCATCACAATCCACAGCAATCTCAAAACCTTATCATGGCACCAATCTCTGGGGTGATGGCAATCACACAGAATTTAAACACCTCTCAGGCACAAAGTGTACCTGTTATCAACAGTGTAGCAGGGAGCCTTGCAGCTTTACAGTCTGTACAGTTTTCACAGCAACTACACAGTCCACATCAGCAGCAAATCATGCAACAGTCTCCGGGGCATATGGCACAGCAGCCATTTATGGCGACTGTGACTCAGCTACAGAATTCACACATGTATGCGCACAAGCAAGAGCCTCCCCAGTATTCCCACACATCTCGTTTTCCTTCAGCCATGGTTGTCACAGATACTAGCAGCATCAGCACATTATCCAACATGTCTTCCAGTAAACAGTGTCCTTTGCAAGCATGGTGATGAACAATATCCAAGGGTTTCATATTTTTGCATCCTGAAGTCTTCTGCTGCTTGTTGCTGCTGATAGGAATAATAAGAAAAGGCCTTTAATGATGGACCTCTAATGTTGGATATACCACGTGAGCTTCTGTACACTTGCATTGTAGTCCCTTTTGCAGTATTTCCAGGAAGAGCATTCAAGGCCAAATTATTTTCTTTAAACAAACAACTGGGAACAGAACAAATTTTAGTGGGAAACTACAGAGAAGGAAGACTAAAGATAAATGGACAACTAAAAACTGAATGTGGAAAGCTATGCATACATTGAACTGAGCCAATGTAAATATTTTTTTTATTAAGACATGAAAACAAAATATTTCTTTATAAGAAGGTAATTTGTTGAATAATTGTAAAAATGTAAAAAAAAAAAAAAA
Protein		NCBI Protein >CAJ82369\|transcription factor 2 [Xenopus tropicalis] PPVSTLTNIHNLSQSVHHNPQQSQNLIMAPISGVMAITQNLNTSQAQSVPVINSVAGSLAALQSVQFSQQLHSPHQQQLMQQSPGHMAQQPFMATVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLSNMSSSKQCPLQAW	Refseq >NP_001083280\|HNF1 homeobox B [Xenopus laevis] MVSKLSPLQQELLNALLNSGVTKEDLIQALEDMIPSPSFGVKLENLHMSPEHEVDSKPVFHTLTNGHHHKGKLSGDEGSEDGDDFDTPPILKELQSLNTEEAAEQRAEVDRMLSEDSWRAAKMIKGYMQQHNIPQREVVDITGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQGSENITDKSSQDQLLFLFPEFNQQNQVQGQPDDTCSEPSNKKMRRNRFKWGPASQHILYQAYERQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSTGPSHPHNLNSLLSHGSPHHTQPSTSPPSKLQGLRYSQQGNNEVTSSSTISHHGNNAMVTSQSILQQVSPVCLDHSHSMLSPDGKLISVSGGGLPPVSTLTNIHNLSQSVHHNPQQSQNLIMAPISGVMAITQNLNTSQAQSVPVINSVAGSLAALQSVQFSQQLHSPHQQQIMQQSPGHMAQQPFMATVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLSNMSSSKQCPLQAW

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.27039	Xl.65135 [+] Xl.15091
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		19 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	HNF1B	OMIM:125853 OMIM:176807 OMIM:137920 OMIM:144700 OMIM:611955
mouse		MGI	Hnf1b	All(5) Targeted, knock Out(1) Targeted, other(3)
zebrafish		ZFIN ZFIN	hnf1bb hnf1ba	32 Lines(s)

Publications
First:		Cloning and developmental expression of LFB3/HNF1 beta transcription factor in Xenopus laevis. [Mech Dev 1994]
Most recent:		HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. [Development 2013]
		View All Papers 3 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding transcription activator activity transcription factor activity
Biological:		positive regulation of transcription regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[R] FOG: Zn-finger

Reagents		tropicalis	laevis
Clones			EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.27039.1.S1_at	Xl.24918.1.A1_s_at [+] Xl.15455.1.S1_s_at Xl.15455.1.S1_at
Affymetrix 2.0			Xl2.15455.1.S1_at [+] Xl2.41321.1.S1_s_at Xl2.15091.1.A1_at

Symbol legend[+]