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Summary Expression Gene Literature (134) GO Terms (22) Nucleotides (196) Proteins (27) Interactants (783) Wiki
XB-GENEPAGE-485690
Gene Symbol: smad4.1

Gene Name: SMAD family member 4, gene 1

Synonyms: XSmad4alpha , Xsmad4 , jip , dpc4 , madh4 , XSmad4a , smad4a , smad4alpha , smad4 ( Add synonyms , Nomenclature history )

Gene Function: signal transduction, tgf-beta pathway

Protein Function :

Interactants: Loading ...
Disease Ontology: juvenile polyposis syndrome [+]

OMIM Diseases: PANCREATIC CANCER [+]

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Xenbase Gene ID XB-GENE-485691 XB-GENE-865543 XB-GENE-17334633
Gene Symbol smad4.1 smad4.1.L smad4.1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 100038088
Entrez Gene: 780764
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine smad4.1 smad4.1.L smad4.1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu052c18      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SMAD4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Smad4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR smad4a ZFIN Ensembl
chicken
GEISHA SMAD4 Ensembl
fruit fly
worm
WORMBASE
Publications
First A human Mad protein acting as a BMP-regulated transcriptional activator., Nature 1996  
Most Recent Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis., Dev Genes Evol 2019          
All View All Papers 20 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 22 terms 7 terms 0 term
PANTHER smad4.1
KEGG Pathways K04501
KOG [TK] TGFbeta receptor signaling protein SMAD and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon
Antibody Smad4 Ab1 Smad4 Ab1 Smad4 Ab1
Morpholino smad4.1 MO1 , smad4.1 MO2 smad4.1 MO1 , smad4.1 MO2 smad4.1 MO1 , smad4.1 MO2
Affymetrix 1.0 Str.51998.1.S1_at Xl.885.1.S1_at [+]
Affymetrix 2.0 Xl2.885.2.S1_a_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.1


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