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Summary Expression Gene Literature (659) GO Terms (7) Nucleotides (88) Proteins (44) Interactants (965) Wiki
XB-GENEPAGE-485904
Gene Symbol:
ins

Gene Name:
insulin

Synonyms:
preproinsulin , insulin I , ins1 , xins , insulin , ins-b , ins-a ( Add synonyms , Nomenclature history )

Gene Function:
peptide hormone

Protein Function :
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synth...[+]


Antibodies: :
Ins Ab3

InterPro :
Insulin-like sf , Insulin family , Insulin CS , Insulin [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
maturity-onset diabetes of the young [+]

OMIM:
MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 1; MODY1 [+]

External Links:
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Xenbase Gene ID XB-GENE-485905 XB-GENE-864803 XB-GENE-6252363
Gene Symbol ins ins.L ins.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100101718
378695
378696
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ins ins.L ins.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards OMIM:Gene, GeneCards INS OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ins2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
zebrafish
ZFIN, AGR ins ZFIN Ensembl
chicken
GEISHA INS Ensembl
fruit fly
worm
Publications
First Translation of messenger ribonucleic acid from isolated pancreatic islets and human insulinomas., Proc Natl Acad Sci U S A 1975  
Most Recent Beneficial actions of the [A14K] analog of the frog skin peptide PGLa-AM1 in mice with obesity and degenerative diabetes: A mechanistic study., Peptides 2021  
All View All Papers 25 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 14 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 7 terms 3 terms 3 terms
PANTHER ins
KEGG Pathways K04526 K04526 K04526
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ins
Antibodies Ins Ab1 , Ins Ab2 , Ins Ab3 Ins Ab1 , Ins Ab2 , Ins Ab3 Ins Ab1 , Ins Ab2 , Ins Ab3
Morpholinos (on-target & off-target) ins MO1 ins MO1 ins MO1
ORFs ins ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info