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Summary Expression Gene Literature (650) GO Terms (6) Nucleotides (68) Proteins (34) Interactants (922) Wiki
XB-GENEPAGE-485904
Gene Symbol: ins

Gene Name: insulin

Synonyms: preproinsulin , insulin I , ins1 , xins , insulin , ins-b , ins-a ( Add synonyms , Nomenclature history )

Gene Function: peptide hormone

Protein Function :
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synth...[+]

Interactants: Loading ...
Disease Ontology: permanent neonatal diabetes mellitus [+]

OMIM Diseases: MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 1; MODY1 [+]

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Xenbase Gene ID XB-GENE-485905 XB-GENE-864803 XB-GENE-6252363
Gene Symbol ins ins.L ins.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 100101718
Entrez Gene: 378695
Entrez Gene: 378696
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL RefSeq TrEMBL Swiss-Prot RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine ins ins.L ins.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards OMIM:Gene, HGNC, GeneCards INS OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ins2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ins ZFIN Ensembl
chicken
GEISHA INS Ensembl
fruit fly
worm
WORMBASE
Publications
First Translation of messenger ribonucleic acid from isolated pancreatic islets and human insulinomas., Proc Natl Acad Sci U S A 1975  
Most Recent Concomitant exposure to benzo[a]pyrene and triclosan at environmentally relevant concentrations induces metabolic syndrome with multigenerational consequences in Silurana (Xenopus) tropicalis., Sci Total Environ 2019  
All View All Papers 25 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 12 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 3 terms 3 terms
PANTHER ins
KEGG Pathways K04526 K04526 K04526
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon
Antibody Ins Ab1 , Ins Ab2 Ins Ab1 , Ins Ab2 Ins Ab1 , Ins Ab2
Morpholino ins MO1 , ins3 MO1 , ins3 MO2 ins MO1 , ins3 MO1 , ins3 MO2 ins MO1 , ins3 MO1 , ins3 MO2
ORF ins ORF1
Affymetrix 1.0 Str.29324.1.S1_at Xl.23623.1.S1_at Xl.817.1.S1_at
Affymetrix 2.0 Xl2.23623.1.S1_at Xl2.817.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.1


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