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Summary Expression Gene Literature (31) GO Terms (8) Nucleotides (1652) Proteins (40) Interactants (572) Wiki
XB-GENEPAGE- 485945

Gene Symbol: tpm1

Gene Name: tropomyosin 1

Synonyms: alpha-tm , alpha-tropomyosin , CH1
Add Xenopus synonyms , Nomenclature history


Gene Function: actin filament coating

Protein Function:
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. S...[+]


Interactants: YYY

OMIM Disease Associations: CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 3; CMH3 [+]
 
Xenbase Gene ID XB-GENE-485946 XB-GENE-865564 XB-GENE-17332885
Gene Symbol tpm1 tpm1.L tpm1.S
Chromosome scaffold_7 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.41716 [+] Xl.34025 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 21 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tpm1 tpm1.L tpm1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TPM1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tpm1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN tpm1 ZFIN Ensembl
chicken
GEISHA TPM1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Isolation and sequence of a cDNA coding for the immunoglobulin mu chain of the sheep. [Mol Immunol 1992]
Most recent: Robust identification of Ptbp1-dependent splicing events by a junction-centric approach in Xenopus laevis. [Dev Biol 2017]
View All Papers 8 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 8 terms 0 term
EC
PANTHER tpm1
KEGG Pathways K10373
KOG [Z] Actin filament-coating protein tropomyosin
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Tpm1 Ab1 Tpm1 Ab1
Morpholino tpm1 MO1 , tpm1 MO2 , tpm1 MO3 tpm1 MO1 , tpm1 MO2 , tpm1 MO3 tpm1 MO1 , tpm1 MO2 , tpm1 MO3
ORF tpm1 ORF1 , Tm7 ORF1
Affymetrix 1.0 Str.41673.1.S1_at [+] Xl.2804.1.S1_at [+]
Affymetrix 2.0 Xl2.2804.1.S1_at [+]

Symbol legend[+]

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