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XB-GENEPAGE-
485984
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Gene Symbol: nkx2-1
Gene Name: NK2 homeobox 1 Synonyms: ttf1 , nkx2.1 , titf1 , Xnkx-2.1 , xnkx2-1 Add Xenopus synonyms , Nomenclature history Gene Function: homeodomain transcription factor Protein Function  :
Interactants: Loading ... 
Disease Ontology: CHOREATIC DISEASE OMIM Diseases: THYROID CANCER, NONMEDULLARY, 1; NMTC1 |
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1/5 | Xenbase Gene ID | XB-GENE-485985 | XB-GENE-865567 | XB-GENE-17336526 | ||||
| Gene Symbol | nkx2-1 | nkx2-1.L | nkx2-1.S | ||||
| Chromosome | Chr08 | chr8L | |||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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| mRNA |
NCBI Nucleotide
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Refseq
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| Protein
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NCBI Protein
TrEMBL
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Refseq
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser | |||||||
| Links |
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| Genomic Synteny | Genomicus PANTHER | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.66443 | Xl.688 | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 53 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | nkx2-1 | nkx2-1.L | nkx2-1.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| human |
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| mouse |
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| zebrafish |
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| chicken |
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| fruit fly |
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| worm |
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| Publications | |||||||
| First: |
Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. [Development 1997]
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| Most recent: |
Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis. [Dev Biol 2018]
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| View All Papers 15 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 4 terms | 3 terms | 0 term | ||||
| PANTHER | nkx2-1 | ||||||
| KEGG Pathways | K09342 | K09342 | |||||
| KOG |
[K] Transcription factor tinman/NKX2-3, contains HOX domain
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | |||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Antibody | Nkx2-1 Ab1 , Nkx2-1 Ab2 | ||||||
| Morpholino | nkx2-1 MO1 , nkx2-1 MO2 | nkx2-1 MO1 , nkx2-1 MO2 | nkx2-1 MO1 , nkx2-1 MO2 | ||||
| Affymetrix 1.0 | Str.39290.1.S1_at [+] | Xl.688.1.S1_at | |||||
| Affymetrix 2.0 | Xl2.688.1.S1_at | ||||||
Symbol legend[+]
