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Summary Expression Gene Literature (58) GO Terms (8) Nucleotides (70) Proteins (28) Interactants (854) Wiki
XB-GENEPAGE-485984

Gene Symbol: nkx2-1

Gene Name: NK2 homeobox 1

Synonyms: ttf1 , nkx2.1 , titf1 , Xnkx-2.1 , xnkx2-1 ( Add synonyms , Nomenclature history )

Gene Function: homeodomain transcription factor

Protein Function :

Interactants: Loading ...
Disease Ontology: choreatic disease [+]

OMIM Diseases: THYROID CANCER, NONMEDULLARY, 1; NMTC1 [+]

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Xenbase Gene ID XB-GENE-485985 XB-GENE-865567 XB-GENE-17336526
Gene Symbol nkx2-1 nkx2-1.L nkx2-1.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine nkx2-1 nkx2-1.L nkx2-1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NKX2-1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Nkx2-1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR nkx2.4b nkx2.1 ZFIN Ensembl
chicken
GEISHA NKX2-1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Gli1 is a target of Sonic hedgehog that induces ventral neural tube development., Development 1997                    
Most Recent Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development., Proc Natl Acad Sci U S A 2018                                    
All View All Papers 15 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 3 terms 0 term
PANTHER nkx2-1
KEGG Pathways K09342 K09342
KOG [K] Transcription factor tinman/NKX2-3, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Nkx2-1 Ab1 , Nkx2-1 Ab2
Morpholino nkx2-1 MO1 , nkx2-1 MO2 nkx2-1 MO1 , nkx2-1 MO2 nkx2-1 MO1 , nkx2-1 MO2
Affymetrix 1.0 Str.39290.1.S1_at [+] Xl.688.1.S1_at
Affymetrix 2.0 Xl2.688.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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