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Summary Expression Gene Literature (50) GO Terms (4) Nucleotides (67) Proteins (27) Interactants (370) Wiki
XB-GENEPAGE- 485984

Gene Symbol: nkx2-1

Gene Name: NK2 homeobox 1

Synonyms: ttf1 , nkx2.1 , titf1 , Xnkx-2.1 , xnkx2-1
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:


Interactants: Loading ...

OMIM Disease Associations: CHOREA, BENIGN HEREDITARY; BHC [+]
1/5
 
Xenbase Gene ID XB-GENE-485985 XB-GENE-865567 XB-GENE-17336526
Gene Symbol nkx2-1 nkx2-1.L nkx2-1.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.66443 Xl.688
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 50 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine nkx2-1 nkx2-1.L nkx2-1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NKX2-1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Nkx2-1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN nkx2.4b nkx2.1 ZFIN Ensembl
chicken
GEISHA NKX2-1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. [Development 1997]
Most recent: Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis. [Dev Biol 2017]
View All Papers 15 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 3 terms 0 term
EC
PANTHER nkx2-1
KEGG Pathways K09342 K09342
KOG [K] Transcription factor tinman/NKX2-3, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Nkx2-1 Ab1 , Nkx2-1 Ab2
Morpholino nkx2-1 MO1 , nkx2-1 MO2 nkx2-1 MO1 , nkx2-1 MO2 nkx2-1 MO1 , nkx2-1 MO2
Affymetrix 1.0 Str.39290.1.S1_at [+] Xl.688.1.S1_at
Affymetrix 2.0 Xl2.688.1.S1_at

Symbol legend[+]

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