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Summary Expression Gene Literature (62) GO Terms (25) Nucleotides (217) Proteins (37) Interactants (501) Wiki
XB-GENEPAGE-486003
Gene Symbol:
smad7

Gene Name:
SMAD family member 7

Synonyms:
xsmad7 , smad8 ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction, TGF-beta pathway

Protein Function :


InterPro :
Ald DH CS GLU , Ald DH N , Ald DH C , Ald DH/histidinol DH [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
colorectal cancer

OMIM:
COLORECTAL CANCER; CRC [+]

External Links:
 
Xenbase Gene ID XB-GENE-486004 XB-GENE-865569 XB-GENE-17334901
Gene Symbol smad7 smad7.L smad7.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100486892
394331
108707343
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine smad7 smad7.L smad7.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tneu095k24      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards SMAD7 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Smad7 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Smad7 Ensembl
zebrafish
ZFIN, AGR smad7 ZFIN Ensembl
chicken
GEISHA SMAD7 Ensembl
fruit fly
Publications
First Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling., Nature 1997  
Most Recent Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network., Elife 2020                        
All View All Papers 6 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 25 terms 9 terms 9 terms
PANTHER smad7
KEGG Pathways K19631 K19631 K19631
KOG [TK] TGFbeta receptor signaling protein SMAD and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks smad7
Morpholinos smad7 MO1 , smad7 MO2 , smad7 MO3 smad7 MO2 , smad7 MO1 , smad7 MO3 smad7 MO1 , smad7 MO2 , smad7 MO3
ORFs smad7.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info