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Summary Expression Gene Literature (57) GO Terms (7) Nucleotides (202) Proteins (24) Interactants (439) Wiki
XB-GENEPAGE- 486003

Gene Symbol: smad7

Gene Name: SMAD family member 7

Synonyms: xsmad7 , smad8
Add Xenopus synonyms , Nomenclature history

Gene Function: signal transduction, TGF-beta pathway

Protein Function :


Interactants: Loading ...

Disease Ontology:
   COLORECTAL CANCER

OMIM Diseases:
   COLORECTAL CANCER; CRC [+]
 

Xenbase Gene ID XB-GENE-486004 XB-GENE-865569 XB-GENE-17334901
Gene Symbol smad7 smad7.L smad7.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.66607 [+] Xl.1228 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 29 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine smad7 smad7.L smad7.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu095k24      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SMAD7 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Smad7 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR smad7 ZFIN Ensembl
chicken
GEISHA SMAD7 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. [Nature 1997]
Most recent: Fibronectin type III and intracellular domains of Toll-like receptor 4 interactor with leucine-rich repeats (Tril) are required for developmental signaling. [Mol Biol Cell 2018]
View All Papers 7 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 7 terms 7 terms
PANTHER smad7
KEGG Pathways K19631 K19631
KOG [TK] TGFbeta receptor signaling protein SMAD and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino smad7 MO1 , smad7 MO2 , smad7 MO3 smad7 MO1 , smad7 MO2 , smad7 MO3 smad7 MO1 , smad7 MO2 , smad7 MO3
ORF smad7.L ORF1
Affymetrix 1.0 Str.37464.1.A1_at [+] Xl.1228.1.S2_at [+]
Affymetrix 2.0 Xl2.1228.1.S2_at [+]

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556