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XB-GENEPAGE-486137
Gene Symbol:
hes2
Gene Name: hes family bHLH transcription factor 2
Synonyms:
XHes2
( Gene Function: helix-loop-helix transcription factor/transcriptional repressor Protein Function
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Transcriptional repressor. Essential in the retina to govern glial versus neuronal differentiation. Promotes gliogenesis through the inhibition of neuronal differentiation by at least two distinct mech...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-486138 | XB-GENE-865581 | XB-GENE-17330530 | |||||
Gene Symbol | hes2 | hes2.L | hes2.S | Chromosome | Chr7 | chr7L | ||
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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CDS |
Gene model
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Gene model
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Entrez Gene |
100038090
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495039
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | hes2 | hes2.L | hes2.S | |||||
Orthology |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Characterization and function of the bHLH-O protein XHes2: insight into the mechanisms controlling retinal cell fate decision., Development 2006 ![]() |
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Most Recent |
Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis., Genes (Basel) 2020 ![]() |
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All | View All Papers 2 paper(s) referencing morpholinos | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 26 terms | 10 terms | 0 term | |||||
PANTHER | hes2 | |||||||
KEGG Pathways | K04280 [+] | K09087 | ||||||
KOG |
[K] Transcriptional repressors of the hairy/E(spl) family (contains HLH)
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | hes2 | |||||||
Morpholinos (on-target & off-target) | hes2 MO2 | hes2 MO1 , hes2 MO2 | ||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | ||||||
Plasmids | Addgene | Addgene |
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