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Summary Expression Gene Literature (16) GO Terms (14) Nucleotides (82) Proteins (39) Interactants (219) Wiki
XB-GENEPAGE-486161
Gene Symbol:
pitx3

Gene Name:
paired like homeodomain 3

Synonyms:
xPitx3 , XPitx-3 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Transcriptional regulator which may play a role in the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons. May play a role in the normal lens development and differentiati...[+]



Interactants:
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Diseases: 


Disease Ontology:
anterior segment mesenchymal dysgenesis [+]

OMIM:
ANTERIOR SEGMENT DYSGENESIS 1; ASGD1 [+]

External Links:
1/7
 
Xenbase Gene ID XB-GENE-486162 XB-GENE-486166 XB-GENE-17345022
Gene Symbol pitx3 pitx3.L pitx3.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100496690
398183
373824
mRNA NCBI Nucleotide RefSeq RefSeq
Protein NCBI Protein RefSeq RefSeq Swiss-Prot Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine pitx3 pitx3.L pitx3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PITX3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pitx3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pitx3 Ensembl
zebrafish
ZFIN, AGR pitx3 ZFIN Ensembl
chicken
GEISHA PITX3 Ensembl
fruit fly
worm
Publications
First Xpitx3: a member of the Rieg/Pitx gene family expressed during pituitary and lens formation in Xenopus laevis., Mech Dev 2001                  
Most Recent Xenopus pitx3 target genes lhx1 and xnr5 are identified using a novel three-fluor flow cytometry-based analysis of promoter activation and repression., Dev Dyn 2017                      
All View All Papers 6 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 4 terms 4 terms
PANTHER pitx3
KEGG Pathways K09357 K09357 K09357
KOG [K] Transcription factor PTX1, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pitx3
Morpholinos pitx3 MO1 pitx3 MO1 pitx3 MO1
Clones Horizon Horizon Source BioScience Horizon

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