pias4 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (7)

Interactants (14)

XB-GENEPAGE-486198

Gene Symbol: pias4 Gene Name: protein inhibitor of activated STAT, 4 Synonyms: piasy, zmiz6, piasg Add Xenopus synonyms Gene Function: zinc finger transcription factor Interactants: sumo2(3) , sumo1(2) , ube2i(2) , brca1(1) , chrd(1) , gata1(1) , mut(1) View All

XB-GENE-486199

XB-GENE-865587

Molecules		tropicalis	laevis
Gene		JGI XT Genome 4.1 Ensembl
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001011455\|Xenopus (Silurana) tropicalis protein inhibitor of activated STAT, 4 (pias4), mRNA GCCAAGATGGCGGCGGAGCTGGTGGAGGCGAAGAACATGGTAATGAGTTTTCGAGTGTCAGATTTGCAAATGCTCCTGGGATTTGTTGGGCGCAGTAAAAGTGGCTTGAAACATGAACTGGTCACACGGGCTCTACAGCTGGTACAGTTTGATTGCAGCCCAGAGGTTTTCAAGAAAATTAAAGAGCTTTATGAAACTCGCTACGCAAAGAAAGGCACAGAGGCAATCTCCCAAGCTCCACCCCAGCCTATCACATCACATCGTGCACCTGAGTCTTTGTCTATTCACCCATCCTATGACCACGGAGTCTCTGGACCCAGGACTTCTCTTTCTACACCTAATATAGACTACCCATCTTTGTATGGGAAACATGTTAATGGGCTCTCAAGGTTGCCTCCAAAAGTTATTACCAAGCCTGAGGTGCGATTGGTCAAGTTGCCTTTCTATGATGTGGTGGATGAACTCTTAAAGCCAACTGAGCTGGTTGCTCAGAACAATGAAAAGTTGCAAGACAGTCCATGTGTTTTCGTCCTGTCCCCAAGGCAAGTGGACTTGATCAAGAACTCCAGGGATTTGCACCCTGGAACCAAATCTGTTCAAGTTGTTCTAAGGATTTGTTACACAGACACGAGCTGTCCACAGGAAGATCAATATCCTCCCAATGTTGCTGTGAAGGTTAATCATAATTACTGCTCTGTTCCGGGATACTACCCTTCAAATAAACCTGGTGTGGAACCTAAAAGACCATGTCGTCCCATTAACCTAACAAACCTCATGTATCTCTCATCTGCTAGCAACCGAGTCACAGTCACTTGGGGTAATTATGGCAAGAGTTATTCTGTGGGTTTATACTTAGTGAGACAAAGAACTTCTTCCGAGCTATTACAGAGATTGAAAACCATTGGTGTGAAACACCCAGAGCTCTGCAAAACCCTTGTGAGAGAGAAGTTACGCCTTGATCCTGATAGTGAAATTGCAACAACAGGGGTCAGAGTGTCTCTTATCTGTCCGCTGGTAAAGATGCGTTTAACTGTGCCGTGCCGAGCTGAGACTTGTGCTCATCTTCAGTGTTTTGATGCAGTTTTTTACTTGCAAATGAATGAAAAGAAACCAACCTGGACATGCCCTGTGTGTGACAAACCTGCCCTTTATGATCAGCTTATCATTGATGGGCTTTTGTCCAAAATTCTCAGTGAGTGCAAAGATGCAGATGAGATTGAGTTCCTTGCAGATGGATCCTGGTGTCCAATTAAAGCAGAGAAGGAAAGAAGTAGTAGTCCTGTATGTCCAATCCTTGTGCTGGGCTCTCAAGACATGATGGCAAAACTTCCTCCTCCAAGCAGCACAGTGTCAAGTGAGAATGGAAAGCCTGGCCCTGATGTGGTGGATCTGACTTTGGACAGCAGTTCGTCTTCATCCTCCTCCTCTGACGAAGACGAAGAAGAGGAGGAGGAGGAACGGCCACCACAGAAAAGACGCTGCTTTGAGAAAGGACTCTTATCAGCTTGTTGACTTTTAGCTGTCTTCAGTCAGACTTACATCTATGAACAGCAGAGACATGAGTCAGATGCGGCAGAGTCCTTTCTTACCAAAAGCTTTATGCATCACTACTTTCACCATGCCTCCCCATATGTCGAACCCCAGAAGAGTAGTAGTGACACTCTGTGCAGCTGCAAAGGGATTAACTTAGCCTTCTTGTTTTCTTAACTTTCTTAGGTTTGGTTTTGGTAGGTGGACAAGGAGGCAAACAGAAGAAATATTTGGCCATTTACTGGCAACTTTCCTCCTTTTTGCTGCTACTGATGAGTAGATCATAATTACTTTTACTTTTGTTAGCTCCTTGGTGCAATCTGGTTCTGGGGTTTTAACTGTCCGAAATGCCTGACCAATGGAGAGAGCATTGGATGAGGTGATTGTTTTTGGGAAAGTGGGGTCGTAGAAATGTATTGAGTTGTAAATATTTACACATAAATAGGAGGAGTGATGACATCTTCATTAAGACTAGGAAGTTCAGAAGCAGTTAATATAGTCTCTCTTTTGCAGGAGAGCAGTAATGGTTCCTCTTTTATCCCGTATTCTTTTTAGTGATATGCAAAAAGCGGGGTGTGTTTATAATCTTTAGGGGCTATGTGGGGGCGGGGAGGGTTTATGCCACGCTTTCAATCCAACTACCTCTATGCTATTCAGGTTTTGTTTCTCTGCTAGATAAGTGGAATGGGGTTAATGCTGCTCTGGACACTATCTTCCTCCTCTCCATCCTCTGCTTTTGTATTACTCATCAGCTTCTTTCCCTTAATACAAGATTCTAAAAGCTGCTTCCCCTCACAATAATCGTATTTCTTCTTTTCCACCGTGAATTAATTATTCATTAAAATTGCTAACTTCACATGCAAGAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001094509\|Xenopus laevis hypothetical LOC494663 (LOC494663), mRNA CTAACGTATGGAAGGATATACGCAAGCGCGAAGAGATCGGAGCCGAGTTAGCAAAGAAGCAATTGGGGATTGGTACATGAGCGCGCGGAATGATCACGTGGGGCGTCGTCGGCCGGCGCGGGGGACGCTGGAAGCCAAGATGGCGGCGGAGTTAGTGGAGGCGAAGAACATGGTAATGAGTTTCCGAGTGTCAGATTTGCAAATGCTCCTAGGATTTGTTGGGCGCAGTAAAAGTGGCTTGAAGCACGAACTGGTCACACGGGCTTTGCAGCTGGTACAGTTTGATTGCAGTCCTGAGGTTTTCAAGAAAATTAAAGAGCTTTATGAGACTCGCTATGCAAAGAAAGGCACAGAGGCAATCTCCCAAGCTCCACCCCAGTCAATTACATCACATCGTCCATCTGAATCTTTGTCTATTCACCCATCGTATGACCATGCAGTCTCTGGACCCAGGACTTCTCTTTCTACACCTAATATAGACTACCCTTCTTTGTATGGGAAACATGTTAATGGGCTCTCTAGGTTGCCTCCAAAAGTTACCACGCCTGAGGTGAGACTGGTCAAGTTGCCTTTCTATGATGTGGTGGATGAACTCTTAAAGCCAACTGAGCTTGTGGCTCAGAACAATGAAAAGTTGCAAGACAGTCCATGTGTGTTTGTCCTGTCCCCAAGGCAAGTGGACATGATCAAGAACTCCAGGGATTTACACCCTGGAACCAAATCTGTTCAAGTGGTCCTGAGGATTTGTTACACAGACACAAGCTGTCCACAGGAAGATCAATATCCTCCCAATATTGCTGTGAAGGTGAATCATAATTACTGCTCTGTTCCGGGATACTACCCTTCAAATAAACCTGGTGTGGAACCTAAGAGACCATGTCGTCCTATTAACCTGACAAACCTGATGTATCTGTCATCTGCCAGCAACAGAGTGACAGTCACTTGGGGGAATTATGGCAAGACTTATTCTGTGGGTTTATACTTAGTAAGACAAAGAACTTCTTCCGAGCTATTACAGAGATTGAAAACCATTGGTGTAAAACATCCAGAGCTCTGCAAAACCCTTGTGAGAGAGAAGTTACGCCTTGATCCTGACAGTGAAATTGCAACAACTGGGGTCAGAGTGTCTCTTATCTGTCCGCTGGTAAAGATGCGGTTAACTGTACCGTGCCGAGCTGAGACTTGTGCTCATCTTCAGTGTTTTGATGCAGTCTTTTACCTGCAAATGAATGAAAAGAAGCCAACCTGGACATGTCCTGTGTGTGACAAACCTGCCCTTTATGATCAGCTTATCATTGATGGGCTTTTGTCCAAAATTCTCAGTGAGTGCAAGGATGCGGATGAGATAGAGTTCCTTGCAGATGGATCCTGGTGTCCAATTAAAGCAGAAAAGGAAAGAAGTAGTAGTCCTGTGTGTCCAATCCTTGTGTTGGGCTCTCAAGACATGATGGCAAAGCTTCCACCACCAAGCAGCACAGTGTCAAGTGAAAATGGAAAGCCTGGTCTTGATGTGGTGGATCTGACTTTAGACAGCAGTTCGTCTTCATCCTCCTCCTCTGACGAAGACGAAGAAGAGGAGGAGGAGGAGGAACGACCACCGCAGAAGAGACGATGCTTTGAGAAAGGACTCTTATCAGCTTGTTGACTTTTAGCTGTGTTCAATCAGACTTACATCTATGAACAGTAGAGATATGAATCGGATGTGGAGTCCTTTCTTACCAAAAGCTTTATGCATCACTACTTTCACCATGCCTCCCCATATGTTGAACCCCACAAGACCTGTAGTGACACTCTATGCAGCTGTGAAGGGATTAATTTAGCCTTTTATTTCCTTAACCTTCTTAGGTTTGGTTTTCATAGATGGACAAGGAGGCAAACCGAAAACATTTTTGGCCATTTACTACCAACTTTCCTCCTTTTGCTGCTACTGATGAGTAGATCATATTTACGTTTCTTTTGTTAGCTACTTGGTGCAATCTGGCTCTGGGGTTTGAACTGTACAAAATGCCTGACCAATGACGAGAGCATTGGGTTAGGTGATTGTGTTTGGGAAAGTGGGGTCATAGAAATGTATCGAGCTGTAAATATTTAAACACAAATAGGAGGATTGATGACATCTTCATTAAGAACTAGGAGGTTCTGAAGCAGTTAATATAGTCTCTCTTCTGCAGGAGAGCAACAATGGTTCCTATTTTATCCCATATTCTTTTTAGTGATATGCAAAAAGCGGGTTGTGTCTTTAGGAGCTGTGCAGGGTTGGGGAGGGTTTATGCCATGCTTTCAATCCAACTACCTCTATGCTATTCAGGTTTTGTTTCTCTGCGCAGTTATGTGGAATGGGGTTAATGCTGCTCTGGACACTTTCTTCCTCCTCTGCATCTTCTGCTTTTGTATTCTTCATCGGCTTCTTTCTCTTAATACAAGATCCTCAAAGCTGCTTCCCCTTACAATAATCATATTCTTTAGTTGAATTATTCATTGAAATTTCTAACTTCACCTGCAAGAGATGCCCTTTCTCTTTTCCATGCACTTACAAGAGGATCATCAAATCTTTCTTTATCATGAATGTACCCTGTACCATCATGCACCATACTGATGTTGGTCTTTCCTGCTGTTGAGAGCCTACTGGTGTTTTAAAGGGGTACTATACACCGTTGTTAAACATGCCTTTGGTGTATACGATTTGTGCTGACCAATTATTTAATTTTTTTTGCCTATTATTTTAATTAAAAAATCTATAGTTTCTGGTTATTTCTTGCACTAAACAGGGCACAACTTGGAACTGTACTTTGATTACTCAGCTTCCTGGTTCTTTAAAAAAAAAATTTGGGAAGAGGCAATTGTTTTGAATTTTCCAGTTTAAACGCCTACGTAATGAACTCCTTTTAACCCGAGAAACCTGCTACAATTGGAGTAAGATAGGAGGCTTGTTTATACAGTATATTAAGTCTATTTACGCAAACTCTCCTGATTTCAGGGGAGGTACTAAGACTAAAAACAATGAAGAATTGCTGCTGTATAATATTTTTTAAAGGATTTTTTTAAATTAAAAGAATAGGCAGAACACCTTTGTTTGCGACTTGTGTTAAAAATGTAAATATAAATATAGCTGTATAATACCCCTTTAATGAAACATCCAGCATCAGCACTGAGTATTTTGGATTTATTACGTCTTGGGTTACAAGCAGAAAATAATATGTTTTAATATGTAGAGGCTGCAGCCTCTTCAACTTACCTTGCTTCACCAAGGAACCACACACTGTTTTAACAGTTCTGTTGACATTATAAAGATCTTGACACTGTTGGTTCAGGATCAGCCACTATTTGTGGCACATTCACAATTTATTTTATTTCTCCTTGTTCTAATTTAATTGTTTTAAAAGCTTCCTGATCATTTTCTAATCTGTGAAAGTTTTTGTTTATATGAAAGTTTTGTTTTTCTTTTTCTTTCCTGTTTGTTTTTTTTTTTGTATGAAAAAAGGCTTTTGCAAAAAAACATCCTGTAGGTTTTTTTTTCTCCCTCTTATCGATTACATCCGCTCGAGTTAAAGAAATAAAAAAAAACAACAACAAAAAAACTCAGAAAAGATAGTGTTAAGAAGAAAAAGAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001011455\|protein inhibitor of activated STAT, 4 [Xenopus (Silurana) tropicalis] MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPEVFKKIKELYETRYAKKGTEAISQAPPQPITSHRAPESLSIHPSYDHGVSGPRTSLSTPNIDYPSLYGKHVNGLSRLPPKVITKPEVRLVKLPFYDVVDELLKPTELVAQNNEKLQDSPCVFVLSPRQVDLIKNSRDLHPGTKSVQVVLRICYTDTSCPQEDQYPPNVAVKVNHNYCSVPGYYPSNKPGVEPKRPCRPINLTNLMYLSSASNRVTVTWGNYGKSYSVGLYLVRQRTSSELLQRLKTIGVKHPELCKTLVREKLRLDPDSEIATTGVRVSLICPLVKMRLTVPCRAETCAHLQCFDAVFYLQMNEKKPTWTCPVCDKPALYDQLIIDGLLSKILSECKDADEIEFLADGSWCPIKAEKERSSSPVCPILVLGSQDMMAKLPPPSSTVSSENGKPGPDVVDLTLDSSSSSSSSSDEDEEEEEEERPPQKRRCFEKGLLSAC	Refseq >NP_001087978\|protein inhibitor of activated STAT, 4 [Xenopus laevis] MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPEVFKKIKELYETRYAKKGTEAISQAPPQSITSHRPSESLSIHPSYDHAVSGPRTSLSTPNIDYPSLYGKHVNGLSRLPPKVTTPEVRLVKLPFYDVVDELLKPTELVAQNNEKLQDSPCVFVLSPRQVDMIKNSRDLHPGTKSVQVVLRICYTDTSCPQEDQYPPNIAVKVNHNYCSVPGYYPSNKPGVEPKRPCRPINLTNLMYLSSASNRVTVTWGNYGKTYSVGLYLVRQRTSSELLQRLKTIGVKHPELCKTLVREKLRLDPDSEIATTGVRVSLICPLVKMRLTVPCRAETCAHLQCFDAVFYLQMNEKKPTWTCPVCDKPALYDQLIIDGLLSKILSECKDADEIEFLADGSWCPIKAEKERSSSPVCPILVLGSQDMMAKLPPPSSTVSSENGKPGLDVVDLTLDSSSSSSSSSDEDEEEEEEEERPPQKRRCFEKGLLSAC

Genomic

tropicalis

Genome Browser

Synteny

Xenbase G-Browse

GBrowse

Expression		tropicalis	laevis
UniGene		Str.36333	Xl.71225
Gurdon EST/FL		XZT16758	IMAGE:6643671
Affymetrix 1.0		Str.36333.1.A1_at [+] Str.11012.1.S1_at Str.50794.1.S1_s_at Str.11012.1.S1_at Str.50794.1.S1_s_at
GEO data			GEO

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene	PIAS4
mouse		MGI	Pias4	All(3) Targeted, knock Out(2) Targeted, other(1)
zebrafish		ZFIN	pias4

Publications
First:		Sumoylation of Smad4, the common Smad mediator of transforming growth factor-beta family signaling. [J Biol Chem 2003]
Most recent:		Rod/Zw10 complex is required for PIASy-dependent centromeric SUMOylation. [J Biol Chem 2010]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding zinc ion binding
Biological:
Cellular Component:
EC:
KOG:		[K] Zn-finger transcription factor

Suppliers		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice	geneservice
		RZPD imagenes	RZPD imagenes

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