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XB-GENEPAGE-486295
Gene Symbol:
fst
Gene Name: follistatin
Synonyms:
xfs
,
follistatin
,
foll
( Gene Function: activin and bmp7 antagonist, also antagonizes bmp2/4 but less effectively Protein Function
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Binds directly to activin and functions as an activin antagonist which plays a role in neural induction. The short isoform is a more potent inhibitor of activin than the long isoform. Specific inhibito...[+]
Interactants:
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Diseases: Disease Ontology:
polycystic ovary syndrome
OMIM:
POLYCYSTIC OVARY SYNDROME 1; PCOS1
External Links:
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Xenbase Gene ID | XB-GENE-486296 | XB-GENE-486300 | XB-GENE-17338212 | |||||
Gene Symbol | fst | fst.L | fst.S | Chromosome | Chr1 | chr1L | chr1S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
493419
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399282
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108707293
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | fst | fst.L | fst.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis., Biochem Biophys Res Commun 1991 |
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Most Recent |
Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., EMBO J 2021 ![]() |
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All | View All Papers 11 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 10 terms | 1 terms | 0 term | |||||
PANTHER | fst | |||||||
KEGG Pathways | K04661 | K04661 | K04661 | |||||
KOG |
[R] FOG: Kazal-type serine protease inhibitor domain
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | fst | |||||||
Morpholinos (on-target & off-target) | fst MO2 , fst MO3 , fst MO4 | fst MO1 , fst MO2 , fst MO3 , fst MO4 | fst MO1 , fst MO2 , fst MO3 , fst MO4 | |||||
ORFs | fst ORF1 | fst.L ORF1 | ||||||
Clones | EXRC Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



