|
XB-GENEPAGE-
486295
|
Gene Symbol: fst
Gene Name: follistatin Synonyms: xfs , follistatin , foll Add Xenopus synonyms , Nomenclature history Gene Function: activin and bmp7 antagonist, also antagonizes bmp2/4 but less effectively Protein Function  :
Binds directly to activin and functions as an activin antagonist which plays a role in neural induction. The short isoform is a more potent inhibitor of activin than the long isoform. Specific inhibito...[+]
Interactants: Loading ... 
Disease Ontology: POLYCYSTIC OVARY SYNDROME OMIM Diseases: POLYCYSTIC OVARY SYNDROME 1; PCOS1 |
|
| Xenbase Gene ID | XB-GENE-486296 | XB-GENE-486300 | XB-GENE-17338212 | ||||
| Gene Symbol | fst | fst.L | fst.S | ||||
| Chromosome | Chr01 | chr1L | chr1S | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
|
Genomic sequence
|
Genomic sequence
|
||||
| CDS |
Gene model
|
||||||
|
Entrez Gene
|
Entrez Gene
|
Entrez Gene
|
|||||
| mRNA |
Refseq
|
Refseq
|
|||||
| Protein
|
Refseq
TrEMBL
TrEMBL
|
Refseq
Swiss-Prot
TrEMBL
|
TrEMBL | ||||
| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
|
||||||
| Links |
|
||||||
| Genomic Synteny | Genomicus PANTHER | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.10666 | Xl.1094 [+] | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
|
|||||
| Experimental regulation |
Regulation heatmap:
|
||||||
| Images | 12 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | fst | fst.L | fst.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
|
||||||
| human |
|
||||||
| mouse |
|
||||||
| zebrafish |
|
||||||
| chicken |
|
||||||
| fruit fly |
|
||||||
| worm |
|
||||||
| Publications | |||||||
| First: | Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis. [Biochem Biophys Res Commun 1991] | ||||||
| Most recent: |
Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads. [Differentiation 9999]
|
||||||
| View All Papers 11 paper(s) referencing morpholinos | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 0 term | 1 terms | 0 term | ||||
| PANTHER | fst | ||||||
| KEGG Pathways | K04661 | K04661 | K04661 | ||||
| KOG |
[R] FOG: Kazal-type serine protease inhibitor domain
|
||||||
| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | EXRC - 1 clone(s) | EXRC - 1 clone(s) | |||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Morpholino | fst MO1 , fst MO2 , fst MO3 , fst MO4 | fst MO1 , fst MO2 , fst MO3 , fst MO4 | fst MO1 , fst MO2 , fst MO3 , fst MO4 | ||||
| ORF | fst ORF1 , fst ORF1 | fst.L ORF1 | |||||
| Affymetrix 1.0 | Str.10666.1.S1_at | Xl.1094.1.S1_at | |||||
| Affymetrix 2.0 | Xl2.1094.2.S1_a_at | ||||||
Symbol legend[+]
