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Summary Expression Gene Literature (134) GO Terms (11) Nucleotides (156) Proteins (52) Interactants (785) Wiki
XB-GENEPAGE-486295
Gene Symbol:
fst

Gene Name:
follistatin

Synonyms:
xfs , follistatin , foll ( Add synonyms , Nomenclature history )

Gene Function:
activin and bmp7 antagonist, also antagonizes bmp2/4 but less effectively

Protein Function :
Binds directly to activin and functions as an activin antagonist which plays a role in neural induction. The short isoform is a more potent inhibitor of activin than the long isoform. Specific inhibito...[+]


InterPro :
TB dom , TB dom sf , Kazal dom sf , Kazal dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
polycystic ovary syndrome

OMIM:
POLYCYSTIC OVARY SYNDROME 1; PCOS1

External Links:
 
Xenbase Gene ID XB-GENE-486296 XB-GENE-486300 XB-GENE-17338212
Gene Symbol fst fst.L fst.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493419
399282
108707293
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine fst fst.L fst.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FST OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fst MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fst Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR fsta fstb ZFIN Ensembl
chicken
GEISHA FST Ensembl
fruit fly
FLYBASE Fst Ensembl
worm
Publications
First Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis., Biochem Biophys Res Commun 1991  
Most Recent Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., EMBO J 2021                          
All View All Papers 11 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 1 terms 0 term
PANTHER fst
KEGG Pathways K04661 K04661 K04661
KOG [R] FOG: Kazal-type serine protease inhibitor domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks fst
Morpholinos (on-target & off-target) fst MO2 , fst MO3 , fst MO4 fst MO1 , fst MO2 , fst MO3 , fst MO4 fst MO1 , fst MO2 , fst MO3 , fst MO4
ORFs fst ORF1 fst.L ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info