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Summary Expression Gene Literature (126) GO Terms (1) Nucleotides (130) Proteins (29) Interactants (712) Wiki
XB-GENEPAGE- 486295

Gene Symbol: fst

Gene Name: follistatin

Synonyms: xfs , follistatin , foll
Add Xenopus synonyms , Nomenclature history

Gene Function: activin and bmp7 antagonist, also antagonizes bmp2/4 but less effectively

Protein Function :
Binds directly to activin and functions as an activin antagonist which plays a role in neural induction. The short isoform is a more potent inhibitor of activin than the long isoform. Specific inhibito...[+]


Interactants: Loading ...

Disease Ontology:
   POLYCYSTIC OVARY SYNDROME

OMIM Diseases:
   POLYCYSTIC OVARY SYNDROME 1; PCOS1
 

Xenbase Gene ID XB-GENE-486296 XB-GENE-486300 XB-GENE-17338212
Gene Symbol fst fst.L fst.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq Swiss-Prot TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.10666 Xl.1094 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 12 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine fst fst.L fst.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FST OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Fst MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR fsta fstb ZFIN Ensembl
chicken
GEISHA FST Ensembl
fruit fly
FLYBASE Fst Ensembl
worm
WORMBASE
Publications
First: Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis. [Biochem Biophys Res Commun 1991]
Most recent: Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads. [Differentiation null]
View All Papers 11 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 1 terms 0 term
PANTHER fst
KEGG Pathways K04661 K04661 K04661
KOG [R] FOG: Kazal-type serine protease inhibitor domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino fst MO1 , fst MO2 , fst MO3 , fst MO4 fst MO1 , fst MO2 , fst MO3 , fst MO4 fst MO1 , fst MO2 , fst MO3 , fst MO4
ORF fst ORF1 fst.L ORF1
Affymetrix 1.0 Str.10666.1.S1_at Xl.1094.1.S1_at
Affymetrix 2.0 Xl2.1094.2.S1_a_at

Symbol legend[+]
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