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Summary Expression Gene Literature (575) GO Terms (13) Nucleotides (164) Proteins (58) Interactants (1880) Wiki
XB-GENEPAGE-486770
Gene Symbol:
gsc

Gene Name:
goosecoid homeobox

Synonyms:
Xgsc , goosecoid , gsc-a , gsc-b ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Plays a central role in executing Spemann's organizer phenomenon (the dorsal blastopore lip of the early Xenopus laevis gastrula can organize a complete secondary body axis when transplanted to another...[+]


InterPro :
Homeobox CS , Homeobox dom , Homeobox-like sf , LATS1 [+]

Interactants:
Loading ...

Diseases: 


OMIM:
SHORT STATURE, AUDITORY CANAL ATRESIA, MANDIBULAR HYPOPLASIA, AND SKELETAL ABNOR

External Links:
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Xenbase Gene ID XB-GENE-486771 XB-GENE-6252605 XB-GENE-864870
Gene Symbol gsc gsc.L gsc.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549458
397752
397748
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gsc gsc.L gsc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GSC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gsc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gsc Ensembl
zebrafish
ZFIN, AGR gsc ZFIN Ensembl
chicken
GEISHA GSC Ensembl
fruit fly
FLYBASE Gsc Ensembl
worm
Publications
First Molecular nature of Spemann''s organizer: the role of the Xenopus homeobox gene goosecoid., Cell 1991                
Most Recent Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage., Biol Open 2021                  
All View All Papers 113 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 16 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 6 terms 6 terms
PANTHER gsc
KEGG Pathways K09324 K09324 K09324
KOG [K] Transcription factor PHOX2/ARIX, contains HOX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gsc
Morpholinos (on-target & off-target) gsc MO1 gsc MO1 gsc MO1
ORFs gsc.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info