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Summary Expression Gene Literature (506) GO Terms (8) Nucleotides (142) Proteins (39) Interactants (1458) Wiki
XB-GENEPAGE- 486770

Gene Symbol: gsc

Gene Name: goosecoid homeobox

Synonyms: Xgsc , goosecoid , gsc-a , gsc-b
Add Xenopus synonyms , Nomenclature history

Gene Function: homeodomain transcription factor

Protein Function:
Plays a central role in executing Spemann's organizer phenomenon (the dorsal blastopore lip of the early Xenopus laevis gastrula can organize a complete secondary body axis when transplanted to another...[+]


Interactants: YYY

OMIM Disease Associations: SHORT STATURE, AUDITORY CANAL ATRESIA, MANDIBULAR HYPOPLASIA...
1/6
 
Xenbase Gene ID XB-GENE-486771 XB-GENE-6252605 XB-GENE-864870
Gene Symbol gsc gsc.L gsc.S
Chromosome scaffold_8 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq NCBI Nucleotide Refseq
Protein Refseq TrEMBL TrEMBL NCBI Protein TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.10803 Xl.801 Xl.797
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 197 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine gsc gsc.L gsc.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GSC OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Gsc MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN gsc ZFIN Ensembl
chicken
GEISHA GSC Ensembl
fruit fly
FLYBASE Gsc Ensembl
worm
WORMBASE
Publications
First: Molecular nature of Spemann''s organizer: the role of the Xenopus homeobox gene goosecoid. [Cell 1991]
Most recent: Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. [Dev Cell 2017]
View All Papers 104 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 3 terms 4 terms
EC
PANTHER gsc
KEGG Pathways K09324 K09324 K09324
KOG [K] Transcription factor PHOX2/ARIX, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 6 clone(s) EXRC - 2 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino gsc MO1 gsc MO1 gsc MO1
ORF gsc ORF1
Affymetrix 1.0 Str.10803.1.S1_s_at [+] Xl.797.1.S1_at [+]
Affymetrix 2.0 Xl2.797.1.S1_at [+]

Symbol legend[+]

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