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XB-GENEPAGE-
486770
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Gene Symbol: gsc
Gene Name: goosecoid homeobox Synonyms: Xgsc , goosecoid , gsc-a , gsc-b Add Xenopus synonyms , Nomenclature history Gene Function: homeodomain transcription factor Protein Function  :
Plays a central role in executing Spemann's organizer phenomenon (the dorsal blastopore lip of the early Xenopus laevis gastrula can organize a complete secondary body axis when transplanted to another...[+]
Interactants: Loading ... 
Disease Ontology: OMIM Diseases: SHORT STATURE, AUDITORY CANAL ATRESIA, MANDIBULAR HYPOPLASIA, AND SKELETAL ABNOR |
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1/6 | Xenbase Gene ID | XB-GENE-486771 | XB-GENE-6252605 | XB-GENE-864870 | ||||||||||
| Gene Symbol | gsc | gsc.L | gsc.S | ||||||||||
| Chromosome | Chr08 | chr8L | chr8S | ||||||||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||||||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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NCBI Nucleotide
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Refseq
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| Protein
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Refseq
TrEMBL
TrEMBL
TrEMBL
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NCBI Protein
TrEMBL
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Refseq
Swiss-Prot
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| Genomic | tropicalis | laevis.L | laevis.S | ||||||||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus | ||||||||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||||||||
| Ensembl | Ensembl | ||||||||||||
| UniGene | Str.10803 | Xl.801 | Xl.797 | ||||||||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 208 expression image(s) for tropicalis and laevis | ||||||||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||||||||
| XenMine | gsc | gsc.L | gsc.S | ||||||||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||||||||
| Smith Morpholino Screen | |||||||||||||
| Orthology |
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| mouse |
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| zebrafish |
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| fruit fly |
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| worm |
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| Publications | |||||||||||||
| First: |
Molecular nature of Spemann''s organizer: the role of the Xenopus homeobox gene goosecoid. [Cell 1991]
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| Most recent: | Tbx2 is required for the suppression of mesendoderm during early Xenopus development. [Dev Dyn 2018] | ||||||||||||
| View All Papers 106 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontology | |||||||||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||||||||
| GO | 7 terms | 3 terms | 4 terms | ||||||||||
| PANTHER | gsc | ||||||||||||
| KEGG Pathways | K09324 | K09324 | K09324 | ||||||||||
| KOG |
[K] Transcription factor PHOX2/ARIX, contains HOX domain
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| Reagents | tropicalis | laevis.L | laevis.S | ||||||||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||||||||
| Clones | EXRC - 6 clone(s) | EXRC - 2 clone(s) | |||||||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||||||||
| Source BioScience | Source BioScience | Source BioScience | |||||||||||
| Morpholino | gsc MO1 | gsc MO1 | gsc MO1 | ||||||||||
| ORF | gsc.S ORF1 | ||||||||||||
| Affymetrix 1.0 | Str.10803.1.S1_s_at [+] | Xl.797.1.S1_at [+] | |||||||||||
| Affymetrix 2.0 | Xl2.797.1.S1_at [+] | ||||||||||||
Symbol legend[+]
