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XB-GENEPAGE-486780
Gene Symbol:
axin1
Gene Name: axin 1
Synonyms:
xAxin
,
axin
,
fused
( Gene Function: negative regulator of the wnt signaling pathway Protein Function
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Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via tw...[+]
Interactants:
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Diseases: Disease Ontology:
hepatocellular carcinoma
OMIM:
HEPATOCELLULAR CARCINOMA
External Links:
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Xenbase Gene ID | XB-GENE-486781 | XB-GENE-17339457 | XB-GENE-865645 | |||||
Gene Symbol | axin1 | axin1.L | axin1.S | Chromosome | Chr9 | chr9_10L | chr9_10S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100498631
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398097
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734298
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | axin1 | axin1.L | axin1.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Xenopus axin interacts with glycogen synthase kinase-3 beta and is expressed in the anterior midbrain., Mech Dev 1999 ![]() |
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Most Recent |
GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery., Cell Rep 2020 ![]() |
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All | View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 49 terms | 13 terms | 9 terms | |||||
PANTHER | axin1 | |||||||
KEGG Pathways | K02157 | K02157 | K02157 | |||||
KOG |
[T] G protein signaling regulators
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | axin1 | |||||||
ORFs | axin1.S ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



