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Summary Expression Gene Literature (165) GO Terms (9) Nucleotides (138) Proteins (65) Interactants (1347) Wiki
XB-GENEPAGE-486800
Gene Symbol:
pax2

Gene Name:
paired box 2

Synonyms:
XPax2 , XPax-2 , pax-2 , pax2-a , pax2-b ( Add synonyms , Nomenclature history )

Gene Function:
paired box transcription factor

Protein Function :
Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 in pronephric morphogenesis during the tailbud stages.


InterPro :
Ig E-set , Sec63-dom , Sec63 , J dom sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
renal coloboma syndrome [+]

OMIM:
PAPILLORENAL SYNDROME; PAPRS [+]

External Links:
1/6
 
Xenbase Gene ID XB-GENE-486801 XB-GENE-486805 XB-GENE-6256440
Gene Symbol pax2 pax2.L pax2.S
Chromosome Chr07 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 733478
379520
398347
mRNA RefSeq RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pax2 pax2.L pax2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PAX2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pax2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pax2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR pax2a pax2b ZFIN Ensembl
chicken
GEISHA PAX2 Ensembl
fruit fly
worm
Publications
First Xenopus Pax-2 displays multiple splice forms during embryogenesis and pronephric kidney development., Mech Dev 1997          
Most Recent Betel quid dependence mechanism and potential cessation therapy., Prog Neuropsychopharmacol Biol Psychiatry 2020  
All View All Papers 44 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 6 terms 8 terms 0 term
PANTHER pax2
KEGG Pathways K15608
KOG [K] Transcription factor PAX2/5/8, contains PAX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pax2
Morpholinos pax2 MO1 , pax2 MO2 , pax2 MO3 pax2 MO1 , pax2 MO2 , pax2 MO3 pax2 MO1 , pax2 MO2 , pax2 MO3
ORFs pax2.L ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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