Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (161) GO Terms (5) Nucleotides (114) Proteins (51) Interactants (1338) Wiki
XB-GENEPAGE-486800

Gene Symbol: pax2

Gene Name: paired box 2

Synonyms: XPax2 , XPax-2 , pax-2 , pax2-a , pax2-b ( Add synonyms , Nomenclature history )

Gene Function: paired box transcription factor

Protein Function :
Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 in pronephric morphogenesis during the tailbud stages.

Interactants: Loading ...
Disease Ontology: renal coloboma syndrome [+]

OMIM Diseases: PAPILLORENAL SYNDROME; PAPRS [+]

1/6
 
Xenbase Gene ID XB-GENE-486801 XB-GENE-486805 XB-GENE-6256440
Gene Symbol pax2 pax2.L pax2.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL Swiss-Prot NCBI Protein
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine pax2 pax2.L pax2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PAX2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Pax2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR pax2a pax2b ZFIN Ensembl
chicken
GEISHA PAX2 Ensembl
fruit fly
worm
WORMBASE
Publications
First Xenopus Pax-2 displays multiple splice forms during embryogenesis and pronephric kidney development., Mech Dev 1997          
Most Recent Distribution and neuronal circuit of spexin 1/2 neurons in the zebrafish CNS., Sci Rep 2019                
All View All Papers 44 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 10 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 5 terms 0 term
PANTHER pax2
KEGG Pathways K15608
KOG [K] Transcription factor PAX2/5/8, contains PAX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)    
Dharmacon Dharmacon Dharmacon
Morpholino pax2 MO1 , pax2 MO2 , pax2 MO3 pax2 MO1 , pax2 MO2 , pax2 MO3 pax2 MO1 , pax2 MO2 , pax2 MO3
ORF pax2.L ORF1
Affymetrix 1.0 Str.10259.1.S1_at [+] Xl.1130.7.S1_s_at [+]
Affymetrix 2.0 Xl2.1130.9.S1_s_at [+] Xl2.29759.1.A1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.4


Major funding for Xenbase is provided by grant P41 HD064556