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Summary Expression Gene Literature (151) GO Terms (8) Nucleotides (120) Proteins (54) Interactants (1247) Wiki
XB-GENEPAGE- 486800

Gene Symbol: pax2

Gene Name: paired box 2

Synonyms: XPax2 , XPax-2 , pax-2 , pax2-a , pax2-b
Add Xenopus synonyms , Nomenclature history

Gene Function: paired box transcription factor

Protein Function :
Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 in pronephric morphogenesis during the tailbud stages.


Interactants: Loading ...

Disease Ontology:
   RENAL COLOBOMA SYNDROME [+]

OMIM Diseases:
   PAPILLORENAL SYNDROME; PAPRS [+]
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Xenbase Gene ID XB-GENE-486801 XB-GENE-486805 XB-GENE-6256440
Gene Symbol pax2 pax2.L pax2.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq NCBI Nucleotide
Protein Refseq TrEMBL TrEMBL Refseq Swiss-Prot TrEMBL NCBI Protein
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.10259 [+] Xl.1130 [+] Xl.29759
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 146 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine pax2 pax2.L pax2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PAX2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Pax2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR pax2a pax2b ZFIN Ensembl
chicken
GEISHA PAX2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Xenopus Pax-2 displays multiple splice forms during embryogenesis and pronephric kidney development. [Mech Dev 1997]
Most recent: lrpap1 as a specific marker of proximal pronephric kidney tubuli in Xenopus laevis embryos. [Int J Dev Biol 2018]
View All Papers 44 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 8 terms 0 term
PANTHER pax2
KEGG Pathways K15608
KOG [K] Transcription factor PAX2/5/8, contains PAX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s) EXRC - 3 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino pax2 MO1 , pax2 MO2 , pax2 MO3 pax2 MO1 , pax2 MO2 , pax2 MO3 pax2 MO1 , pax2 MO2 , pax2 MO3
ORF pax2.L ORF1 , pax2.L ORF2
Affymetrix 1.0 Str.10259.1.S1_at [+] Xl.1130.7.S1_s_at [+]
Affymetrix 2.0 Xl2.1130.9.S1_s_at [+] Xl2.29759.1.A1_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556