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XB-GENEPAGE-486816
Gene Symbol:
irx1
Gene Name: iroquois homeobox 1
Synonyms:
Xiro
,
Xiro1
,
irx1-a
,
irx1-b
,
iro
( Gene Function: homeodomain transcription factor Protein Function
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Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Acts early in neural...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID
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XB-GENE-486817 | XB-GENE-865648 | XB-GENE-6254076 | |||||
Gene Symbol | irx1 | irx1.L | irx1.S | Chromosome | Chr6 | chr6L | chr6S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100038208
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397976
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735237
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | irx1 | irx1.L | irx1.S | |||||
Orthology ![]() |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
Xiro, a Xenopus homolog of the Drosophila Iroquois complex genes, controls development at the neural plate., EMBO J 1998 |
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Most Recent |
Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., EMBO J 2021 ![]() |
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All | View All Papers 7 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 34 terms | 28 terms | 22 terms | |||||
PANTHER | irx1 | |||||||
KEGG Pathways | ||||||||
KOG |
[K] Transcription factor MEIS1 and related HOX domain proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | irx1 | |||||||
Morpholinos | Irx1 MO2 , irx1 MO1 | Irx1 MO2 , irx1 MO1 | Irx1 MO2 , irx1 MO1 | |||||
ORFs | irx1.S ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
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