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Summary Expression Gene Literature (81) GO Terms (20) Nucleotides (60) Proteins (32) Interactants (848) Wiki
XB-GENEPAGE-486854

Gene Symbol: tbx5

Gene Name: T-box 5

Synonyms: xtbx5 , tbx-5 , xtbx-5 , tbx5-a , tbx5-b ( Add Xenopus synonyms , Nomenclature history )

Gene Function: T-box transcription factor

Protein Function :
DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation (PubMed:10079235). May bind to the core DNA motif of promoters.

Interactants: Loading ...
Disease Ontology: Holt-Oram syndrome

OMIM Diseases: HOLT-ORAM SYNDROME; HOS

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Xenbase Gene ID XB-GENE-486855 XB-GENE-865653 XB-GENE-6253071
Gene Symbol tbx5 tbx5.L tbx5.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq TrEMBL TrEMBL Swiss-Prot RefSeq TrEMBL Swiss-Prot NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine tbx5 tbx5.L tbx5.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TBX5 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tbx5 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR tbx5a tbx5b ZFIN Ensembl
chicken
GEISHA TBX5 Ensembl
fruit fly
worm
WORMBASE
Publications
First Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19., Genomics 1999  
Most Recent The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis., Dev Biol 2019                            
All View All Papers 17 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 20 terms 4 terms 4 terms
PANTHER tbx5
KEGG Pathways K10179 K10179
KOG [K] TBX2 and related T-box transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino tbx5 MO1 , tbx5 MO2 tbx5 MO1 , tbx5 MO2 tbx5 MO1 , tbx5 MO2
Affymetrix 1.0 Str.49463.1.S1_at [+] Xl.529.1.S1_at Xl.21542.1.S1_s_at [+]
Affymetrix 2.0 Xl2.529.1.S1_at Xl2.21542.1.S1_s_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.11.3


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