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XB-GENEPAGE-486854
Gene Symbol:
tbx5
Gene Name: T-box 5
Synonyms:
xtbx5
,
tbx-5
,
xtbx-5
,
tbx5-a
,
tbx5-b
( Gene Function: T-box transcription factor Protein Function
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DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation (PubMed:10079235). May bind to the core DNA motif of promoters.
Interactants:
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Diseases: Disease Ontology:
Holt-Oram syndrome
OMIM:
HOLT-ORAM SYNDROME; HOS
External Links:
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Xenbase Gene ID | XB-GENE-486855 | XB-GENE-865653 | XB-GENE-6253071 | |||||
Gene Symbol | tbx5 | tbx5.L | tbx5.S | Chromosome | Chr1 | chr1L | chr1S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
619589
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373738
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373556
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | tbx5 | tbx5.L | tbx5.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19., Genomics 1999 |
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Most Recent |
RA Signaling in Limb Development and Regeneration in Different Species., Subcell Biochem 2020 |
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All | View All Papers 17 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 53 terms | 22 terms | 4 terms | |||||
PANTHER | tbx5 | |||||||
KEGG Pathways | K04695 | K10179 | K10179 | |||||
KOG |
[K] TBX2 and related T-box transcription factors
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | tbx5 | |||||||
Mutants | Xtr.tbx5emHorb | |||||||
Morpholinos | tbx5 MO1 , tbx5 MO2 | tbx5 MO1 , tbx5 MO2 | tbx5 MO1 , tbx5 MO2 | |||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
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