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Summary Expression Gene Literature (39) GO Terms (1) Nucleotides (195) Proteins (27) Interactants (757) Wiki
XB-GENEPAGE-486940

Gene Symbol: prickle1

Gene Name: prickle planar cell polarity protein 1

Synonyms: prickle , XPk , Prickle-b , XPk-1 , prickle1-b , prickle1-a , prickle A , prickle B ( Add Xenopus synonyms , Nomenclature history )

Gene Function: nuclear receptor, may be a negative regulator of the Wnt/beta-catenin signaling pathway [Entrez]

Protein Function :
Acts in a planar cell polarity (PCP) complex; polarization along the apical/basal axis of epithelial cells. Regulates the polarized assembly of fibronectrin on the surface of the mesoderm during gastru...[+]

Interactants: Loading ...
Disease Ontology: progressive myoclonus epilepsy

OMIM Diseases: EPILEPSY, PROGRESSIVE MYOCLONIC, 1B; EPM1B

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Xenbase Gene ID XB-GENE-486941 XB-GENE-6251800 XB-GENE-865659
Gene Symbol prickle1 prickle1.L prickle1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL Swiss-Prot RefSeq Swiss-Prot RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine prickle1 prickle1.L prickle1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PRICKLE1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Prickle1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR prickle1a prickle1b ZFIN Ensembl
chicken
GEISHA PRICKLE1 Ensembl
fruit fly
worm
WORMBASE
Publications
First The localization of p34cdc2 in the cells of normal, hyperplastic, and malignant epithelial and lymphoid tissues of the oral cavity., J Pathol 1996  
Most Recent Topologically correct central projections of tetrapod inner ear afferents require Fzd3., Sci Rep 2019                
All View All Papers 5 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 1 terms 0 term 1 terms
PANTHER prickle1
KEGG Pathways K04511 K04511 K04511
KOG [TZR] FOG: LIM domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino prickle1 MO1 , prickle1 MO2 prickle1 MO1 , prickle1 MO2 prickle1 MO1 , prickle1 MO2
ORF prickle1.L ORF1 prickle1.S ORF1
Affymetrix 1.0 Str.1773.1.S1_at Xl.12111.1.S1_at Xl.7556.1.S1_at
Affymetrix 2.0 Xl2.12111.1.S1_s_at [+] Xl2.7556.1.S1_a_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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