Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (54) GO Terms (3) Nucleotides (355) Proteins (27) Interactants (292) Wiki
XB-GENEPAGE- 486986

Gene Symbol: tnni3

Gene Name: troponin I3, cardiac type

Synonyms: cardiac troponin I , TnIc , ctnIc , cTNT , cardiac tropin T , XTnIc , c-troponin , XcTnI , cTnI , troponin-ic , tnnic
Add Xenopus synonyms , Nomenclature history


Gene Function: Troponin I

Protein Function:
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.


Interactants: Loading ...

OMIM Disease Associations: CARDIOMYOPATHY, FAMILIAL RESTRICTIVE, 1; RCM1 [+]
1/8
 
Xenbase Gene ID XB-GENE-486987 XB-GENE-865663 XB-GENE-17334604
Gene Symbol tnni3 tnni3.L tnni3.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.8477 [+] Xl.1518 Xl.935
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 80 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tnni3 tnni3.L tnni3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TNNI3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tnni3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
tnni3k ZFIN Ensembl
chicken
GEISHA TNNI3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Cardiac troponin I is a heart-specific marker in the Xenopus embryo: expression during abnormal heart morphogenesis. [Dev Biol 1994]
Most recent: Frizzled-7 is required for Xenopus heart development. [Biol Open 2017]
View All Papers 20 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 1 terms 1 terms 3 terms
EC
PANTHER tnni3
KEGG Pathways K12044 K12044 K12044
KOG [Z] Troponin I
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Tnni3 Ab1
ORF tnni3 ORF1
Affymetrix 1.0 Str.8477.1.S1_at [+] Xl.1518.1.S1_at Xl.935.1.S1_at
Affymetrix 2.0 Xl2.1518.1.S1_at Xl2.935.1.S1_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.6.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556