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Summary Expression Gene Literature (81) GO Terms (6) Nucleotides (358) Proteins (28) Interactants (473) Wiki
XB-GENEPAGE-486986

Gene Symbol: tnni3

Gene Name: troponin I3, cardiac type

Synonyms: cardiac troponin I , TnIc , ctnIc , cTNT , cardiac tropin T , XTnIc , c-troponin , XcTnI , cTnI , troponin-ic , tnnic , TIc ( Add Xenopus synonyms , Nomenclature history )

Gene Function: Troponin I

Protein Function :
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Interactants: Loading ...
Disease Ontology: dilated cardiomyopathy 2A [+]

OMIM Diseases: CARDIOMYOPATHY, FAMILIAL RESTRICTIVE, 1; RCM1 [+]

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Xenbase Gene ID XB-GENE-486987 XB-GENE-865663 XB-GENE-17334604
Gene Symbol tnni3 tnni3.L tnni3.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL TrEMBL Refseq TrEMBL Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tnni3 tnni3.L tnni3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TNNI3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tnni3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
tnni3k ZFIN Ensembl
chicken
GEISHA TNNI3 Ensembl
fruit fly
worm
WORMBASE
Publications
First Expression cloning of a human B1 bradykinin receptor., J Biol Chem 1994  
Most Recent The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis., Dev Biol 2019                            
All View All Papers 27 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 1 terms 3 terms
PANTHER tnni3
KEGG Pathways K12044 K12044 K12044
KOG [Z] Troponin I
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
Dharmacon Dharmacon Dharmacon
Antibody Tnni3 Ab1
ORF tnni3 ORF1 tnni3.L ORF1
Affymetrix 1.0 Str.8477.1.S1_at [+] Xl.1518.1.S1_at Xl.935.1.S1_at
Affymetrix 2.0 Xl2.1518.1.S1_at Xl2.935.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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