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Summary Expression Gene Literature (85) GO Terms (11) Nucleotides (375) Proteins (41) Interactants (490) Wiki
XB-GENEPAGE-486986
Gene Symbol:
tnni3

Gene Name:
troponin I3, cardiac type

Synonyms:
cardiac troponin I , TnIc , ctnIc , cTNT , cardiac tropin T , XTnIc , c-troponin , XcTnI , cTnI , troponin-ic , tnnic , TIc ( Add synonyms , Nomenclature history )

Gene Function:
Troponin I

Protein Function :
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.


InterPro :
Troponin , Troponin-I N , Troponin sf , JmjC dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
hypertrophic cardiomyopathy 7 [+]

OMIM:
CARDIOMYOPATHY, FAMILIAL RESTRICTIVE, 1; RCM1 [+]

External Links:
1/8
 
Xenbase Gene ID XB-GENE-486987 XB-GENE-865663 XB-GENE-17334604
Gene Symbol tnni3 tnni3.L tnni3.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 496889
494826
397803
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tnni3 tnni3.L tnni3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TNNI3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tnni3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tnni3 Ensembl
zebrafish
tnni3k Ensembl
chicken
GEISHA TNNI3 Ensembl
fruit fly
worm
Publications
First Precocious appearance of cardiac troponin T pre-mRNAs during early avian embryonic skeletal muscle development in ovo., Dev Biol 1990  
Most Recent Smooth Muscle in Cardiac Chambers is Common in Turtles and Extensive in the Emydid Turtle, Trachemys scripta., Anat Rec (Hoboken) 2020                
All View All Papers 27 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 1 terms 3 terms
PANTHER tnni3
KEGG Pathways K12044 K12044 K12044
KOG [Z] Troponin I
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tnni3
Antibodies Tnni3 Ab1
ORFs tnni3 ORF1 tnni3.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info