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Summary Expression Gene Literature (264) GO Terms (24) Nucleotides (104) Proteins (38) Interactants (1081) Wiki
XB-GENEPAGE-487001
Gene Symbol:
fgf2

Gene Name:
fibroblast growth factor 2

Synonyms:
HBGF-2 , bfgf , fgf-2 , basic fgf , xfgf2 ( Add synonyms , Nomenclature history )

Gene Function:
heparin-binding growth factor

Protein Function :
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell...[+]


InterPro :
IL1/FGF , FGF2 , Fibroblast GF fam , Oxysterol-bd [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-487002 XB-GENE-487006 XB-GENE-17339645
Gene Symbol fgf2 fgf2.L fgf2.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 550087
100101279
108706695
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine fgf2 fgf2.L fgf2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards FGF2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fgf2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fgf2 Ensembl
zebrafish
ZFIN, AGR fgf2 ZFIN Ensembl
chicken
GEISHA FGF2 Ensembl
fruit fly
Publications
First Mesoderm induction in early Xenopus embryos by heparin-binding growth factors., Nature 1987  
Most Recent Tissue disaggregation and isolation of specific cell types from transgenic Xenopus appendages for transcriptional analysis by FACS., Dev Dyn 2020  
All View All Papers 20 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 16 terms 5 terms
PANTHER fgf2
KEGG Pathways K18497 K18497 K18497
KOG [T] Fibroblast growth factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks fgf2
Antibodies FGF2 Ab1 , Fgf2 Ab2 Fgf2 Ab2
Morpholinos fgf2 MO1 fgf2 MO1 fgf2 MO1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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