Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (19) GO Terms (18) Nucleotides (267) Proteins (36) Interactants (374) Wiki
XB-GENEPAGE-487021
Gene Symbol:
fzd2

Gene Name:
frizzled class receptor 2

Synonyms:
mgc89887 , Fz-2 , Xfz2 , frizzled-2 , frizzled2 , fz2 ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane receptor in the wnt signaling pathway

Protein Function :
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nucl...[+]



Interactants:
Loading ...

Diseases: 


External Links:
1/6
 
Xenbase Gene ID XB-GENE-487022 XB-GENE-17339021 XB-GENE-865666
Gene Symbol fzd2 fzd2.L fzd2.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 493345
399141
mRNA RefSeq RefSeq
Protein RefSeq RefSeq Swiss-Prot Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine fzd2 fzd2.L fzd2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu059i07      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FZD2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fzd2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fzd2 Ensembl
zebrafish
ZFIN, AGR fzd2 ZFIN Ensembl
chicken
GEISHA FZD2 Ensembl
fruit fly
worm
Publications
First Xenopus frizzled-2 is expressed highly in the developing eye, otic vesicle and somites., Mech Dev 1999        
Most Recent eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled., J Biol Chem 2020            
All View All Papers 5 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 18 terms 0 term 5 terms
PANTHER fzd2
KEGG Pathways K02235 K02235
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks fzd2
Antibodies Fzd2 Ab1 Fzd2 Ab1
Morpholinos fzd2 MO1 , fzd2 MO2 , fzd2 MO3 fzd2 MO1 , fzd2 MO2 , fzd2 MO3 fzd2 MO1 , fzd2 MO2 , fzd2 MO3
ORFs fzd2.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556