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Summary Expression Gene Literature (122) GO Terms (17) Nucleotides (122) Proteins (46) Interactants (934) Wiki
XB-GENEPAGE-487158
Gene Symbol:
hhex

Gene Name:
hematopoietically expressed homeobox

Synonyms:
XHex , tHex , hex ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Regulates the differentiation of both endothelial and blood cells. Probably plays a role in the proliferation of vascular endothelial...[+]


InterPro :
Homeobox metazoa , Homeobox CS , Homeobox dom , Homeobox-like sf [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-487159 XB-GENE-865680 XB-GENE-17345658
Gene Symbol hhex hhex.L hhex.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 395060
373590
108697398
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hhex hhex.L hhex.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HHEX OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hhex MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hhex Ensembl
zebrafish
ZFIN, AGR hhex ZFIN Ensembl
chicken
GEISHA HHEX Ensembl
fruit fly
FLYBASE HHEX Ensembl
worm
Publications
First Activation and blocking of neuronal nicotinic acetylcholine receptor reconstituted in Xenopus oocytes., Proc Natl Acad Sci U S A 1990  
Most Recent Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation., Cell Rep 2019                            
All View All Papers 41 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 14 terms 5 terms
PANTHER hhex
KEGG Pathways K08024 K08024 K08024
KOG [K] Transcription factor HEX, contains HOX and HALZ domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hhex
Transgenes Tg(hhex:rtTA;TRE:{dn}Rab11a-GFP) Tg(hhex:rtTA;TRE:{dn}Rab11a-GFP) Tg(hhex:rtTA;TRE:{dn}Rab11a-GFP)
Morpholinos (on-target & off-target) hhex MO1 hhex MO1 hhex MO1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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