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XB-GENEPAGE-487168
Gene Symbol:
nodal1
Gene Name: nodal homolog 1
Synonyms:
nr1
,
Xnr-1
,
Xnr1
,
nodal-related 1
,
nr1-a
,
spaw
,
nodal
( Gene Function: transforming growth factor beta and bone morphogenetic protein related protein Protein Function
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Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activa...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-487169 | XB-GENE-865681 | XB-GENE-17337560 | |||||
Gene Symbol | nodal1 | nodal1.L | nodal1.S | Chromosome | Chr3 | chr3L | chr3S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.2
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
549075
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378543
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108712673
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | nodal1 | nodal1.L | nodal1.S | |||||
Phenotype | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Smith Morpholino Screen | tgas124h10 | |||||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Effects of ionic concentration on permeability properties of nodal membrane in myelinated nerve fibres of Xenopus laevis. Potential clamp experiments., Acta Physiol Scand 1973 |
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Most Recent |
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage., Biol Open 2021 ![]() |
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All | View All Papers 95 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 20 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 18 terms | 11 terms | 2 terms | |||||
PANTHER | nodal1 | |||||||
KEGG Pathways | K04666 | K04666 | K04666 | |||||
KOG |
[T] Transforming growth factor beta, bone morphogenetic protein and related proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | nodal1 | |||||||
Morpholinos (on-target & off-target) | nodal1 MO2 , nodal1 MO4 , nodal1 MO5 , nodal1 MO7 , nodal1 MO8 | nodal1 MO3 , nodal1 MO1 , nodal1 MO2 , nodal1 MO4 , nodal1 MO6 , nodal1 MO5 , nodal1 MO7 | nodal1 MO3 , nodal1 MO1 , nodal1 MO2 , nodal1 MO4 , nodal1 MO6 , nodal1 MO5 , nodal1 MO7 | |||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
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