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XB-GENEPAGE-
487168
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Gene Symbol: nodal1
Gene Name: nodal homolog 1 Synonyms: nr1 , Xnr-1 , Xnr1 , nodal-related 1 , nr1-a , spaw , nodal Add Xenopus synonyms , Nomenclature history Gene Function: transforming growth factor beta and bone morphogenetic protein related protein Protein Function  :
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activa...[+]
Interactants: Loading ... 
Disease Ontology Associations: OMIM Disease Associations: |
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1/6 | Xenbase Gene ID | XB-GENE-487169 | XB-GENE-865681 | XB-GENE-17337560 | ||||
| Gene Symbol | nodal1 | nodal1.L | nodal1.S | ||||
| Chromosome | Chr03 | chr3L | chr3S | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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Gene model
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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| Protein
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Refseq
Swiss-Prot
TrEMBL
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Refseq
Swiss-Prot
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
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| Genomic Synteny | Genomicus | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.26907 | Xl.1037 | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 46 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | nodal1 | nodal1.L | nodal1.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | tgas124h10 | ||||||
| Orthology |
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| Publications | |||||||
| First: | Effects of ionic concentration on permeability properties of nodal membrane in myelinated nerve fibres of Xenopus laevis. Potential clamp experiments. [Acta Physiol Scand 1973] | ||||||
| Most recent: | TGF-β Family Signaling in Early Vertebrate Development. [Cold Spring Harb Perspect Biol 2018] | ||||||
| View All Papers 105 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 12 paper(s) referencing Disease Ontologies | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 16 terms | 12 terms | 0 term | ||||
| PANTHER | nodal1 | ||||||
| KEGG Pathways | K04666 | K04666 | |||||
| KOG |
[T] Transforming growth factor beta, bone morphogenetic protein and related proteins
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | EXRC - 2 clone(s) | ||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Morpholino | nodal1 MO1 , nodal1 MO2 , nodal1 MO3 , nodal1 MO4 , nodal1 MO5 , nodal1 MO6 , nodal1 MO7 , nodal1 MO8 | nodal1 MO1 , nodal1 MO2 , nodal1 MO3 , nodal1 MO4 , nodal1 MO5 , nodal1 MO6 , nodal1 MO7 , nodal1 MO8 | nodal1 MO1 , nodal1 MO2 , nodal1 MO3 , nodal1 MO4 , nodal1 MO5 , nodal1 MO6 , nodal1 MO7 , nodal1 MO8 | ||||
| Affymetrix 1.0 | Str.26907.1.S1_at | Xl.1037.1.S1_at | |||||
| Affymetrix 2.0 | Xl2.1037.1.S1_at | ||||||
Symbol legend[+]
