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Summary Expression Gene Literature (563) GO Terms (22) Nucleotides (63) Proteins (39) Interactants (1609) Wiki
XB-GENEPAGE-487168
Gene Symbol:
nodal1

Gene Name:
nodal homolog 1

Synonyms:
nr1 , Xnr-1 , Xnr1 , nodal-related 1 , nr1-a , spaw , nodal ( Add synonyms , Nomenclature history )

Gene Function:
transforming growth factor beta and bone morphogenetic protein related protein

Protein Function :
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activa...[+]


InterPro :
Ig-like dom , Ig/MHC CS , Ig-like fold , Ig-like dom sf [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-487169 XB-GENE-865681 XB-GENE-17337560
Gene Symbol nodal1 nodal1.L nodal1.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549075
378543
108712673
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine nodal1 nodal1.L nodal1.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tgas124h10      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
Protein Atlas
mouse
rat
zebrafish
ZFIN, AGR spaw ZFIN Ensembl
chicken
GEISHA NODAL Ensembl
fruit fly
worm
Publications
First Effects of ionic concentration on permeability properties of nodal membrane in myelinated nerve fibres of Xenopus laevis. Potential clamp experiments., Acta Physiol Scand 1973  
Most Recent Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage., Biol Open 2021                  
All View All Papers 95 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 20 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 11 terms 2 terms
PANTHER nodal1
KEGG Pathways K04666 K04666 K04666
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks nodal1
Morpholinos (on-target & off-target) nodal1 MO2 , nodal1 MO4 , nodal1 MO5 , nodal1 MO7 , nodal1 MO8 nodal1 MO3 , nodal1 MO1 , nodal1 MO2 , nodal1 MO4 , nodal1 MO6 , nodal1 MO5 , nodal1 MO7 nodal1 MO3 , nodal1 MO1 , nodal1 MO2 , nodal1 MO4 , nodal1 MO6 , nodal1 MO5 , nodal1 MO7
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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