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Summary Expression Gene Literature (557) GO Terms (21) Nucleotides (61) Proteins (38) Interactants (1551) Wiki
XB-GENEPAGE-487168
Gene Symbol:
nodal1

Gene Name:
nodal homolog 1

Synonyms:
nr1 , Xnr-1 , Xnr1 , nodal-related 1 , nr1-a , spaw , nodal ( Add synonyms , Nomenclature history )

Gene Function:
transforming growth factor beta and bone morphogenetic protein related protein

Protein Function :
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activa...[+]


InterPro :
Ig-like dom , Ig/MHC CS , Ig-like fold , Ig-like dom sf [+]

Interactants:
Loading ...

Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-487169 XB-GENE-865681 XB-GENE-17337560
Gene Symbol nodal1 nodal1.L nodal1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549075
378543
108712673
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot Swiss-Prot Swiss-Prot NCBI Protein
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine nodal1 nodal1.L nodal1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas124h10      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
Protein Atlas
mouse
rat
zebrafish
ZFIN, AGR spaw ZFIN Ensembl
chicken
GEISHA NODAL Ensembl
fruit fly
worm
Publications
First Effects of ionic concentration on permeability properties of nodal membrane in myelinated nerve fibres of Xenopus laevis. Potential clamp experiments., Acta Physiol Scand 1973  
Most Recent Alkylglycerol monooxygenase, a heterotaxy candidate gene, regulates left-right patterning via Wnt signaling., Dev Biol 2019          
All View All Papers 95 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 17 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 17 terms 11 terms 2 terms
PANTHER nodal1
KEGG Pathways K04666 K04666 K04666
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks nodal1
Morpholinos nodal1 MO1 , nodal1 MO2 , nodal1 MO3 , nodal1 MO4 , nodal1 MO5 , nodal1 MO6 , nodal1 MO7 , nodal1 MO8 nodal1 MO1 , nodal1 MO2 , nodal1 MO3 , nodal1 MO4 , nodal1 MO5 , nodal1 MO6 , nodal1 MO7 , nodal1 MO8 nodal1 MO1 , nodal1 MO2 , nodal1 MO3 , nodal1 MO4 , nodal1 MO5 , nodal1 MO6 , nodal1 MO7 , nodal1 MO8
Clones Horizon Source BioScience Horizon Source BioScience Horizon

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