Gene Symbol: nodal1 [provisional] Gene Name: nodal homolog 1 [provisional] Synonyms: nr1, Xnr-1, Xnr1, nodal-related 1, induction of axial mesoderm, nr1-a Add Xenopus synonyms Gene Function: transforming growth factor beta and bone morphogenetic protein related protein Interactants: grin1(203) , grin2a(116) , nodal2(96) , grin2b(95) , nodal(60) , grin2c(44) , grin2d(28) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016321|Xenopus (Silurana) tropicalis nodal homolog 1 (nodal1), mRNA CTCCCCGCAAGAGAGAGAACAGCAGCACAAGGATGGCATTTCTGACAGCAGTCCTGTGCTTTGGTTTTGCCTGCATGGTGCAAGGGGTGCCCTCCTGGCTAGAGAGCAGAATTCCTCTCTTAGGATCCAGTGTGGCATCAAAGCACCCGAGTCTGCTTGATGGAAACAGACATCATAGAGACATGAAATACCCTTTTTATATGATGCAGCTGTACCAGAACCTTGTCATGGCAAACGATACAGGGCTTGCCCGTGGGCACAACACTGCCACTAAGGAATACGACACTGTTCTGAGTCTCTTTGCAAAAAGGTGCATGGAAAGTGAGAAACGTTGGACGCTGTCCTTTGACATGTCAGCTGTCTCCAAGAGCAGTGAGCTGAAGTTGGCAGAACTAAGGATTCAGCTTCCACACATTGAAATGTCACACAATGTGACCGTAGATGTGTACCACACTAGAGATGGGGAAGAGAATCTCTATCTGGGATCATTTGAGGCAAACCCTTTCTCTACCAAAGGCTCACCATGGAAAGTCTTTAACGTAACTAGGATTCTGCAGCATTATTTCAAGGAAGGGCAGGATATTAAAAGTGAATACCTAAGAACAAAGGACAGGGCAGAGAGAGGCTCGGGTATGAGCAGTGCAGAGTTCCTAGATTCCCCGGGAGATTCCCCACAGTATAATCCCCATCATACCCCTCTGCGTAGATATCTTTCTACAGAGGGAGTCATGCTTGTGTTGTTTACCAAAGTCAAGCCCTCTGTCAACCACATTGGCTTTCCCAGCCTCATCAAGACAGCGGAGTCATCCAAATATGTTGACATGGAGAAAGCTAGCAGGATGCCTGGTATTAGGAGACACAGGCGGAACAAGAATGAGAAGCATCACTTATCCATGGGAAGCATCCCATCCAGACATGTTGATAATGGGAAACCTCTCTGTCGAAGAGTGGACATGATTGTGAACTTTGAAGACATCGGATGGGGCAACTGGATTGTCTATCCAAAAAAGTACAACGCTTACAGGTGCGAGGGAGCGTGTCCAATTCCACTCAACGAGACCTTCAAACCAACAAACCACGCCTACATGAAAAGTGTGGTCAAGTTGTACCAGCCCGAAAAAGTGGAGTGTCCATTGTGCGTCCCGATAAAGATGAGCCCTCTCTCAATGTTGTATTATGAGGGCGACGAGGTTGTTTTAAGGCACCACCAAGAGATGATTGTAGAGGAGTGTGGGTGCAGTTAAATATGTTTCCTAGCCTACACAGTAACTGTTGTCATTTATATCCATCCCTTCTGTATGAAAAGTGTGTAAATATCATGTAGATATGTAAATAGTGGAGATGTATATTTTGTATTTATTAATGGTAGTAATAAGCAATTATTTGTGTCAAATTAAAGATATGCGGGTTTAAACATTTGTATTATTTTTGCTATTTTGATAAGTTATGCTTTGGTTCTGTTGCAATAAACTATAAAACTTAAAAAAAAAAAAAAAAAA	Refseq >NM_001085796|Xenopus laevis nodal homolog 1 (nodal1), mRNA CTCTGAGAGTGTTACATCTCCCTGAAAGAGAGATCAGCAGTGCAAGCATGGCATTTCTGACAGCAGTCCTGTACTTAGGTTTCGCATGCATATCACAAGGATTGCCCACCTGGCCAGATAGAGTAGAGAGCAGGAATCCTCTCTTCGGATCCAGAGTGGCGTTAAACCTCCCAAGCCTACTGGATGGAAACAGACATCATAGAGATATGAGATATCCTTTATATATGATGCAGCTGTACCAGAATCTTGTCACGGGAAATGATACAGGTCTTGCCAATCGGCCAAACACTGCCACGAAGGAATATGATACCGTTCTGAGTCTCTTTGCAAAAAAGTGCACCGAAAGTGAGAACCGTTGGACACTGTCTTTTGACATGTCGGCTGTCTCCCGGAGTAATGAACTGAAGTTGGCAGAACTAAGAATTCTACTTCCTCACACTGAACCATCACACAATATTACCATGGATATGTACCACAGTAGGGATGGTGAAGACAATCTCTACCTGGGATCATTTAATGCAAACCCTCCTTCTACCAAAGGCTCACCATGGAAAGTTTTTAACGTAACCAAGATCCTACAGCCTTATTTCAAGGAAAGAAGGGATATTGATAGTGAACACCTAAAAGCAAAGGAAAGGGCAGAGAGAGGCTCAGGTATGAGCAATGCAGAGTTCATAGATGCCCCAGGTCCTTCCCAACAATACAATCCTCATCAAACATCTGTCCCTACATACCTCAATACCAAGGGAGTCATGCTAGTGTTGTTTACTAAAGTCAAGTCCTCTGCCAACCATATTGGCTTTCCCAGCCTCATCAAGACAGCAGAGTCATCCAAATACGTTGACATAGAGAAAGCTAGTAGAGTGCCTGGTATTAGGAGACACAGAAGGAACAGGAATGAAAACCATCACTTATCAATAGGAAGCATCCCTTCCAGGCATGTCGAAAATGGGAAACCTCTTTGTAGGAGAGTGGACATGATTGTGGACTTTGAGGACATTGGATGGAGCAGCTGGATTGTCTACCCAAAAAAGTACAATGCTTATAGATGTGAGGGAGCTTGTCCAATTCCACTAAATGAGACCTTCAAACCAACAAACCATGCCTATATGAAAAGTGTGGTCAAGTTGTACCAACCCGAACGAGTGGAGTGTCCATTGTGCGTCCCGGTGAAGATGAGCCCACTCTCCATGTTGTATTATGAGGGAGATGAGGTTGTTTTGAGGCACCACCAAGAGATGATTGTAGAGGAATGTGGGTGCAGTTAATGATTTTACTGGCCTACAAAACAATAGCTGCCATTTATATCTAATAATCCCTTCTGCAAAAAAATGTGTGTAAATGTGTATGTAGATATGTAAATAATTGAGATGTATATTTGGTATTTATTCATGGTAGGGATAAGCAAATTAAATATTTGTGTCAAATTAAAGTATGTGTATTGAAACATTTGTATTATGTTTGCTGTTTTGATAAGTTATGCCTTGGCTTTGTTGCAATAAACTATAAAACATA
Protein		Refseq >NP_001016321|nodal homolog precursor [Xenopus (Silurana) tropicalis] MAFLTAVLCFGFACMVQGVPSWLESRIPLLGSSVASKHPSLLDGNRHHRDMKYPFYMMQLYQNLVMANDTGLARGHNTATKEYDTVLSLFAKRCMESEKRWTLSFDMSAVSKSSELKLAELRIQLPHIEMSHNVTVDVYHTRDGEENLYLGSFEANPFSTKGSPWKVFNVTRILQHYFKEGQDIKSEYLRTKDRAERGSGMSSAEFLDSPGDSPQYNPHHTPLRRYLSTEGVMLVLFTKVKPSVNHIGFPSLIKTAESSKYVDMEKASRMPGIRRHRRNKNEKHHLSMGSIPSRHVDNGKPLCRRVDMIVNFEDIGWGNWIVYPKKYNAYRCEGACPIPLNETFKPTNHAYMKSVVKLYQPEKVECPLCVPIKMSPLSMLYYEGDEVVLRHHQEMIVEECGCS UniProtKB	Refseq >NP_001079265|nodal homolog precursor [Xenopus laevis] MAFLTAVLYLGFACISQGLPTWPDRVESRNPLFGSRVALNLPSLLDGNRHHRDMRYPLYMMQLYQNLVTGNDTGLANRPNTATKEYDTVLSLFAKKCTESENRWTLSFDMSAVSRSNELKLAELRILLPHTEPSHNITMDMYHSRDGEDNLYLGSFNANPPSTKGSPWKVFNVTKILQPYFKERRDIDSEHLKAKERAERGSGMSNAEFIDAPGPSQQYNPHQTSVPTYLNTKGVMLVLFTKVKSSANHIGFPSLIKTAESSKYVDIEKASRVPGIRRHRRNRNENHHLSIGSIPSRHVENGKPLCRRVDMIVDFEDIGWSSWIVYPKKYNAYRCEGACPIPLNETFKPTNHAYMKSVVKLYQPERVECPLCVPVKMSPLSMLYYEGDEVVLRHHQEMIVEECGCS UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.26907	Xl.1037
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		20 expression image(s) for tropicalis and laevis

Phenotype		tropicalis	laevis
Smith Morpholino Screen		tgas124h10

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human
mouse
zebrafish		ZFIN	spaw	3 Lines(s)

Publications
First:		Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor. [Science 1992]
Most recent:		Serotonin has early, cilia-independent roles in Xenopus left-right patterning. [Dis Model Mech 2013]
		View All Papers 24 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		growth factor activity
Biological:
Cellular Component:		extracellular region
EC:
KOG:		[T] Transforming growth factor beta, bone morphogenetic protein and related proteins

Reagents		tropicalis	laevis
Clones			EXRC - 2 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.26907.1.S1_at	Xl.1037.1.S1_at
Affymetrix 2.0			Xl2.1037.1.S1_at

Symbol legend[+]

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