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Summary Expression Gene Literature (247) GO Terms (47) Nucleotides (1061) Proteins (38) Interactants (1551) Wiki
XB-GENEPAGE-487199
Gene Symbol: ctnnb1

Gene Name: catenin beta 1

Synonyms: beta-catenin , ctnnb1-b , ctnnb1-a , B-catenin , beta catenin ( Add synonyms , Nomenclature history )

Gene Function: adherens junction protein/component of wnt signaling pathway

Protein Function :
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr...[+]

Interactants: Loading ...
Disease Ontology: medulloblastoma [+]

OMIM Diseases: MEDULLOBLASTOMA; MDB [+]

GEO Series : GSE93195.
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Xenbase Gene ID XB-GENE-487200 XB-GENE-6254184 XB-GENE-487204
Gene Symbol ctnnb1 ctnnb1.L ctnnb1.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 549712
Entrez Gene: 399274
Entrez Gene: 380441
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL RefSeq TrEMBL TrEMBL RefSeq TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ctnnb1 ctnnb1.L ctnnb1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CTNNB1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ctnnb1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ctnnb1 ZFIN Ensembl
chicken
GEISHA CTNNB1 Ensembl
fruit fly
worm
WORMBASE
Publications
First The armadillo homologs beta-catenin and plakoglobin are differentially expressed during early development of Xenopus laevis., Dev Biol 1992            
Most Recent ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia., Cell Rep 2019                                
All View All Papers 42 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 17 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 23 terms 24 terms 10 terms
PANTHER ctnnb1
KEGG Pathways K02105 K02105 K02105
KOG [TZ] Armadillo/beta-Catenin/plakoglobin
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon
Antibody Ctnnb1 Ab2 , Ctnnb1 Ab3 , Ctnnb1 Ab1 , Ctnnb1 Ab4 , Ctnnb1 Ab5 , Ctnnb1 Ab6 , Ctnnb1 Ab7 , Ctnnb1 Ab8 , Ctnnb1 Ab9 , Ctnnb1 Ab10 , Ctnnb1 Ab11 , Ctnnb1 Ab12 , Ctnnb1 Ab 11 , Ctnnb1 Ab13 , Ctnnb1 AB16 Ctnnb1 Ab2 , Ctnnb1 Ab3 , Ctnnb1 Ab1 , Ctnnb1 Ab4 , Ctnnb1 Ab5 , Ctnnb1 Ab6 , Ctnnb1 Ab7 , Ctnnb1 Ab8 , Ctnnb1 Ab9 , Ctnnb1 Ab10 , Ctnnb1 Ab11 , Ctnnb1 Ab12 , Ctnnb1 Ab 11 , Ctnnb1 Ab13 , Ctnnb1 AB16 Ctnnb1 Ab2 , Ctnnb1 Ab3 , Ctnnb1 Ab1 , Ctnnb1 Ab4 , Ctnnb1 Ab5 , Ctnnb1 Ab6 , Ctnnb1 Ab7 , Ctnnb1 Ab8 , Ctnnb1 Ab9 , Ctnnb1 Ab10 , Ctnnb1 Ab11 , Ctnnb1 Ab12 , Ctnnb1 Ab 11 , Ctnnb1 Ab13 , Ctnnb1 AB16
Morpholino ctnnb1 MO1 , ctnnb1 MO2 , ctnnb1 MO3 ctnnb1 MO1 , ctnnb1 MO2 , ctnnb1 MO3 ctnnb1 MO1 , ctnnb1 MO2 , ctnnb1 MO3
ORF ctnnb1.L ORF1 , ctnnb1.L ORF2 ctnnb1.S ORF1 , ctnnb1.S ORF2
Affymetrix 1.0 Str.43438.1.A1_at [+] Xl.23136.1.S1_at [+] Xl.1639.1.S1_at
Affymetrix 2.0 Xl2.23136.1.S2_at [+] Xl2.1639.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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