Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (144) GO Terms (23) Nucleotides (137) Proteins (44) Interactants (1300) Wiki
XB-GENEPAGE-487288
Gene Symbol: foxd3

Gene Name: forkhead box D3

Synonyms: XFD-6 , xfoxd3 , fkh6 , foxd3-a , foxd3-b ( Add synonyms , Nomenclature history )

Gene Function: forkhead domain transcription factor

Protein Function :
Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction. Functions by recruiting the transcriptional corepressor tle4. Also acts in a nega...[+]

Interactants: Loading ...
Diseases:  OMIM: AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 1; AIS1

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
1/4
 
Xenbase Gene ID XB-GENE-487289 XB-GENE-865691 XB-GENE-6252892
Gene Symbol foxd3 foxd3.L foxd3.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 496851
373548
373610
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine foxd3 foxd3.L foxd3.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FOXD3 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Foxd3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR foxd3 ZFIN Ensembl
chicken
GEISHA FOXD3 Ensembl
fruit fly
worm
WORMBASE
Publications
First A fork head related multigene family is transcribed in Xenopus laevis embryos., Int J Dev Biol 1996    
Most Recent Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction., Dev Biol 2020          
All View All Papers 47 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 21 terms 9 terms 8 terms
PANTHER foxd3
KEGG Pathways K09397 K09397 K09397
KOG [K] Forkhead/HNF-3-related transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks foxd3
Morpholinos foxd3 MO1 , foxd3 MO2 foxd3 MO1 , foxd3 MO2 foxd3 MO1 , foxd3 MO2
ORFs foxd3 ORF1 foxd3.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.13.1
Major funding for Xenbase is provided by grant P41 HD064556