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Summary Expression Gene Literature (146) GO Terms (23) Nucleotides (139) Proteins (46) Interactants (1323) Wiki
XB-GENEPAGE-487288
Gene Symbol:
foxd3

Gene Name:
forkhead box D3

Synonyms:
XFD-6 , xfoxd3 , fkh6 , foxd3-a , foxd3-b ( Add synonyms , Nomenclature history )

Gene Function:
forkhead domain transcription factor

Protein Function :
Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction. Functions by recruiting the transcriptional corepressor tle4. Also acts in a nega...[+]



Interactants:
Loading ...

Diseases: 


OMIM:
AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 1; AIS1

External Links:
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Xenbase Gene ID XB-GENE-487289 XB-GENE-865691 XB-GENE-6252892
Gene Symbol foxd3 foxd3.L foxd3.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 496851
373548
373610
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine foxd3 foxd3.L foxd3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FOXD3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Foxd3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Foxd3 Ensembl
zebrafish
ZFIN, AGR foxd3 ZFIN Ensembl
chicken
GEISHA FOXD3 Ensembl
fruit fly
worm
Publications
First A fork head related multigene family is transcribed in Xenopus laevis embryos., Int J Dev Biol 1996    
Most Recent The transcription factor Hypermethylated in Cancer 1 (Hic1) regulates neural crest migration via interaction with Wnt signaling., Dev Biol 2020  
All View All Papers 47 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 10 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 9 terms 8 terms
PANTHER foxd3
KEGG Pathways K09397 K09397 K09397
KOG [K] Forkhead/HNF-3-related transcription factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks foxd3
Morpholinos foxd3 MO1 , foxd3 MO2 foxd3 MO1 , foxd3 MO2 foxd3 MO1 , foxd3 MO2
ORFs foxd3 ORF1 foxd3.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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