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Summary Expression Gene Literature (137) GO Terms (23) Nucleotides (123) Proteins (38) Interactants (1285) Wiki
XB-GENEPAGE-487288
Gene Symbol: foxd3

Gene Name: forkhead box D3

Synonyms: XFD-6 , xfoxd3 , fkh6 , foxd3-a , foxd3-b ( Add synonyms , Nomenclature history )

Gene Function: forkhead domain transcription factor

Protein Function :
Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction. Functions by recruiting the transcriptional corepressor tle4. Also acts in a nega...[+]

Interactants: Loading ...
OMIM Diseases: AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 1; AIS1

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Xenbase Gene ID XB-GENE-487289 XB-GENE-865691 XB-GENE-6252892
Gene Symbol foxd3 foxd3.L foxd3.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 496851
Entrez Gene: 373548
Entrez Gene: 373610
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine foxd3 foxd3.L foxd3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FOXD3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Foxd3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR foxd3 ZFIN Ensembl
chicken
GEISHA FOXD3 Ensembl
fruit fly
worm
WORMBASE
Publications
First A fork head related multigene family is transcribed in Xenopus laevis embryos., Int J Dev Biol 1996    
Most Recent The neural border: Induction, specification and maturation of the territory that generates neural crest cells., Dev Biol 2018      
All View All Papers 47 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 21 terms 9 terms 8 terms
PANTHER foxd3
KEGG Pathways K09397 K09397 K09397
KOG [K] Forkhead/HNF-3-related transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)    
Dharmacon Dharmacon
Morpholino foxd3 MO1 , foxd3 MO2 foxd3 MO1 , foxd3 MO2 foxd3 MO1 , foxd3 MO2
ORF foxd3 ORF1 foxd3.S ORF1
Affymetrix 1.0 Str.11302.1.S1_at Xl.525.1.S1_at Xl.523.1.S1_at
Affymetrix 2.0 Xl2.525.1.S1_at Xl2.523.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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