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XB-GENEPAGE-
487288
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Gene Symbol: foxd3
Gene Name: forkhead box D3 Synonyms: XFD-6 , xfoxd3 , fkh6 , foxd3-a , foxd3-b Add Xenopus synonyms , Nomenclature history Gene Function: forkhead domain transcription factor Protein Function  :
Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction. Functions by recruiting the transcriptional corepressor tle4. Also acts in a nega...[+]
Interactants: Loading ... 
Disease Ontology: OMIM Diseases: AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 1; AIS1 |
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1/4 | Xenbase Gene ID | XB-GENE-487289 | XB-GENE-865691 | XB-GENE-6252892 | ||||
| Gene Symbol | foxd3 | foxd3.L | foxd3.S | ||||
| Chromosome | Chr04 | chr4L | chr4S | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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Refseq
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| Protein
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Refseq
Swiss-Prot
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Refseq
Swiss-Prot
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Refseq
Swiss-Prot
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus PANTHER | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.11302 | Xl.525 | Xl.523 | ||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 140 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | foxd3 | foxd3.L | foxd3.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| mouse |
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| zebrafish |
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| chicken |
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| fruit fly |
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| worm |
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| Publications | |||||||
| First: |
A fork head related multigene family is transcribed in Xenopus laevis embryos. [Int J Dev Biol 1996]
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| Most recent: |
The b-HLH transcription factor Hes3 participates in neural plate border formation by interfering with Wnt/β-catenin signaling. [Dev Biol 2018]
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| View All Papers 45 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 21 terms | 10 terms | 9 terms | ||||
| PANTHER | foxd3 | ||||||
| KEGG Pathways | K09397 | K09397 | K09397 | ||||
| KOG |
[K] Forkhead/HNF-3-related transcription factor
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | EXRC - 2 clone(s) | ||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | Source BioScience | |||||
| Morpholino | foxd3 MO1 , foxd3 MO2 | foxd3 MO1 , foxd3 MO2 | foxd3 MO1 , foxd3 MO2 | ||||
| ORF | foxd3 ORF1 , foxd3 ORF1 | foxd3.S ORF1 | |||||
| Affymetrix 1.0 | Str.11302.1.S1_at | Xl.525.1.S1_at | Xl.523.1.S1_at | ||||
| Affymetrix 2.0 | Xl2.525.1.S1_at | Xl2.523.1.S1_at | |||||
Symbol legend[+]
