Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (46) GO Terms (24) Nucleotides (138) Proteins (28) Interactants (509) Wiki
XB-GENEPAGE- 487308

Gene Symbol: gdf3

Gene Name: growth differentiation factor 3

Synonyms: derrière , derriere , vgr2 , vgr-2 , gdf-3
Add Xenopus synonyms , Nomenclature history


Gene Function: tgf-beta related peptide growth factor

Protein Function:
Required for posterior mesoderm formation during embryogenesis. Acts indirectly to suppress head formation by altering mesodermal patterning. Also involved in the establishment of left-right axis asymm...[+]


Interactants: YYY

OMIM Disease Associations: KLIPPEL-FEIL SYNDROME 3, AUTOSOMAL DOMINANT; KFS3 [+]
1/2
 
Xenbase Gene ID XB-GENE-487309 XB-GENE-17343554 XB-GENE-865693
Gene Symbol gdf3 gdf3.L gdf3.S
Chromosome Chr01 Scaffold21
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.16175 Xl.457
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 55 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine gdf3 gdf3.L gdf3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GDF3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Gdf3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN gdf3 ZFIN Ensembl
chicken
GEISHA GDF3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Isolation of Vgr-2, a novel member of the transforming growth factor-beta-related gene family. [Mol Endocrinol 1992]
Most recent: Genome organization of the vg1 and nodal3 gene clusters in the allotetraploid frog Xenopus laevis. [Dev Biol 2017]
View All Papers 11 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 0 term 17 terms
EC
PANTHER gdf3
KEGG Pathways K05495 K05495
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)   EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Gdf3 Ab1 Gdf3 Ab1
Morpholino gdf3 MO1 gdf3 MO1 gdf3 MO1
Affymetrix 1.0 Str.16175.1.S1_a_at [+] Xl.457.1.S1_at
Affymetrix 2.0 Xl2.457.1.S1_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556