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Summary Expression Gene Literature (55) GO Terms (24) Nucleotides (140) Proteins (29) Interactants (665) Wiki
XB-GENEPAGE- 487308

Gene Symbol: gdf3

Gene Name: growth differentiation factor 3

Synonyms: derrière , derriere , vgr2 , vgr-2 , gdf-3
Add Xenopus synonyms , Nomenclature history


Gene Function: tgf-beta related peptide growth factor

Protein Function :
Required for posterior mesoderm formation during embryogenesis. Acts indirectly to suppress head formation by altering mesodermal patterning. Also involved in the establishment of left-right axis asymm...[+]


Interactants: Loading ...

Disease Ontology:
   ISOLATED MICROPHTHALMIA 7 [+]

OMIM Diseases:
   KLIPPEL-FEIL SYNDROME 3, AUTOSOMAL DOMINANT; KFS3 [+]
1/2
 

Xenbase Gene ID XB-GENE-487309 XB-GENE-17343554 XB-GENE-865693
Gene Symbol gdf3 gdf3.L gdf3.S
Chromosome Chr01 Scaffold21
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.16175 Xl.457
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 58 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine gdf3 gdf3.L gdf3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GDF3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Gdf3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR gdf3 ZFIN Ensembl
chicken
GEISHA GDF3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Identification and cloning of localized maternal RNAs from Xenopus eggs. [Cell 1985]
Most recent: Tbx2 is required for the suppression of mesendoderm during early Xenopus development. [Dev Dyn 2018]
View All Papers 11 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 0 term 17 terms
PANTHER gdf3
KEGG Pathways K05495 K05495
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)   EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Gdf3 Ab1 Gdf3 Ab1
Morpholino gdf3 MO1 gdf3 MO1 gdf3 MO1
Affymetrix 1.0 Str.16175.1.S1_a_at [+] Xl.457.1.S1_at
Affymetrix 2.0 Xl2.457.1.S1_at

Symbol legend[+]
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Version: 4.9.1
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556