Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (328) GO Terms (9) Nucleotides (120) Proteins (39) Interactants (1868) Wiki
XB-GENEPAGE-487370
Gene Symbol: snai2

Gene Name: snail family zinc finger 2

Synonyms: xslug , xSlu , slug , Snail2 , XSnail2 , snai2-a , snai2-b ( Add synonyms , Nomenclature history )

Gene Function: zinc finger transcriptional repressor

Protein Function :
Probable transcriptional repressor. Acts downstream of snai1 in the specification of the neural crest and neural crest migration.


Interactants: Loading ...
Disease Ontology: Waardenburg syndrome type 2D [+]

OMIM Diseases: PIEBALD TRAIT; PBT [+]

1/4
 
Xenbase Gene ID XB-GENE-487371 XB-GENE-6255814 XB-GENE-865699
Gene Symbol snai2 snai2.L snai2.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.1
CDS Gene model
Entrez Gene: 395065
Entrez Gene: 379440
Entrez Gene: 398235
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL Swiss-Prot RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine snai2 snai2.L snai2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SNAI2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Snai2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR snai2 ZFIN Ensembl
chicken
GEISHA SNAI2 Ensembl
fruit fly
worm
WORMBASE
Publications
First Expression of Xenopus snail in mesoderm and prospective neural fold ectoderm., Dev Dyn 1993                
Most Recent Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome., Cell 2019                                  
All View All Papers 114 paper(s) referencing morpholinos 15 paper(s) referencing OMIMs 22 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 7 terms 2 terms
PANTHER snai2
KEGG Pathways K05706 K05706 K05706
KOG [K] C2H2-type Zn-finger protein
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)    
Horizon Horizon Horizon
Antibody Snai2 Ab1 Snai2 Ab1 Snai2 Ab1
Transgene Tg(alpha-3000:ihh) Tg(alpha-3000:ihh) Tg(alpha-3000:ihh)
Morpholino snai2 MO1 , snai2 MO2 , snai2 MO3 snai2 MO1 , snai2 MO2 , snai2 MO3 snai2 MO1 , snai2 MO2 , snai2 MO3
ORF snai2 ORF1 snai2.L ORF1 snai2.S ORF1
Affymetrix 1.0 Str.2.1.S1_at Xl.3818.1.S1_at Xl.11972.1.S1_at
Affymetrix 2.0 Xl2.3818.1.S1_at Xl2.11972.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.3


Major funding for Xenbase is provided by grant P41 HD064556