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Summary Expression Gene Literature (52) GO Terms (57) Nucleotides (145) Proteins (36) Interactants (662) Wiki
XB-GENEPAGE-487419
Gene Symbol:
smo

Gene Name:
smoothened, frizzled class receptor

Synonyms:
XSmo , X-smoothened , smoothened ( Add synonyms , Nomenclature history )

Gene Function:
hedgehog signal transduction

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
basal cell carcinoma

OMIM:
BASAL CELL CARCINOMA, SUSCEPTIBILITY TO, 1; BCC1 [+]

External Links:
1/3
 
Xenbase Gene ID XB-GENE-487420 XB-GENE-487424 XB-GENE-17333650
Gene Symbol smo smo.L smo.S
Chromosome Chr03 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100491644
100190780
398216
mRNA NCBI Nucleotide RefSeq RefSeq
Protein NCBI Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine smo smo.L smo.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SMO OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Smo MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Smo Ensembl
zebrafish
ZFIN, AGR smo ZFIN Ensembl
chicken
GEISHA SMO Ensembl
fruit fly
FLYBASE smo Ensembl
worm
Publications
First The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants., Development 1998  
Most Recent Smoothened stimulation by membrane sterols drives Hedgehog pathway activity., Nature 2019  
All View All Papers 8 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 56 terms 5 terms 6 terms
PANTHER smo
KEGG Pathways K06226 K06226 K06226
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks smo
Antibodies Smo Ab1 Smo Ab1
Morpholinos smo MO1 smo MO1 smo MO1
Clones EXRC Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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