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XB-GENEPAGE-
487473
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Gene Symbol: nodal2
Gene Name: nodal homolog 2 Synonyms: Xnr-2 , Xnr2 , nr2 Add Xenopus synonyms , Nomenclature history Gene Function: transforming growth factor beta and bone morphogenetic protein related protein Protein Function  :
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activa...[+]
Interactants: Loading ... 
Disease Ontology: OMIM Diseases: |
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1/2 | Xenbase Gene ID | XB-GENE-487474 | XB-GENE-865706 | XB-GENE-17344717 | ||||
| Gene Symbol | nodal2 | nodal2.L | nodal2.S | ||||
| Chromosome | Chr03 | chr3L | chr3S | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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| mRNA |
NCBI Nucleotide
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Refseq
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| Protein
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NCBI Protein
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Refseq
Swiss-Prot
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.36384 | Xl.1038 | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 12 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | nodal2 | nodal2.L | nodal2.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| zebrafish |
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| fruit fly |
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| Publications | |||||||
| First: | Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor. [Science 1992] | ||||||
| Most recent: |
Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis. [Proc Natl Acad Sci U S A 2017]
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| View All Papers 24 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 0 term | 12 terms | 0 term | ||||
| PANTHER | nodal2 | ||||||
| KEGG Pathways | |||||||
| KOG |
[T] Transforming growth factor beta, bone morphogenetic protein and related proteins
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | EXRC - 1 clone(s) | ||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Morpholino | nodal2 MO1 , nodal2 MO2 | nodal2 MO1 , nodal2 MO2 | nodal2 MO1 , nodal2 MO2 | ||||
| Affymetrix 1.0 | Str.36384.1.S1_at [+] | Xl.1038.1.S1_at | |||||
| Affymetrix 2.0 | Xl2.1038.1.S1_at | ||||||
Symbol legend[+]
