Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (165) GO Terms (12) Nucleotides (80) Proteins (36) Interactants (491) Wiki
XB-GENEPAGE-487473
Gene Symbol:
nodal2

Gene Name:
nodal homolog 2

Synonyms:
Xnr-2 , Xnr2 , nr2 ( Add synonyms , Nomenclature history )

Gene Function:
transforming growth factor beta and bone morphogenetic protein related protein

Protein Function :
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activa...[+]


Interactants:
Loading ...

Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-487474 XB-GENE-865706 XB-GENE-17344717
Gene Symbol nodal2 nodal2.L nodal2.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 100491883
397835
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine nodal2 nodal2.L nodal2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
Protein Atlas
mouse
rat
zebrafish
chicken
fruit fly
worm
Publications
First Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor., Science 1992  
Most Recent Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Proc Natl Acad Sci U S A 2018            
All View All Papers 24 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 2 terms 12 terms 0 term
PANTHER nodal2
KEGG Pathways K04666
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks nodal2
Morpholinos nodal2 MO1 , nodal2 MO2 nodal2 MO1 , nodal2 MO2 nodal2 MO1 , nodal2 MO2
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556