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Summary Expression Gene Literature (98) GO Terms (7) Nucleotides (109) Proteins (41) Interactants (440) Wiki
XB-GENEPAGE-487489
Gene Symbol:
dio3

Gene Name:
deiodinase, iodothyronine, type 3

Synonyms:
iodothyronine 5-deiodinase type III , 5DIII , type 3 deiodinase , D3 , DI-3 ( Add synonyms , Nomenclature history )

Gene Function:
thyroxine 5'-deiodinase

Protein Function :
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-487490 XB-GENE-865707 XB-GENE-17336015
Gene Symbol dio3 dio3.L dio3.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100038242
397779
447383
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dio3 dio3.L dio3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards DIO3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dio3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dio3 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR dio3b dio3a ZFIN Ensembl
chicken
GEISHA DIO3 Ensembl
fruit fly
Publications
First Comparison of the effects of vitamin A on limb development and regeneration in Xenopus laevis tadpoles., J Embryol Exp Morphol 1986          
Most Recent Thyroid Disrupting Chemicals in mixture Perturb Thymocyte Differentiation in Xenopus laevis tadpoles., Toxicol Sci 2021  
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 3 terms 6 terms 2 terms
PANTHER dio3
KEGG Pathways K07754 K07754 K07754
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dio3
Morpholinos dio3 MO1
ORFs dio3.L ORF1 dio3.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info