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Summary Expression Gene Literature (6) GO Terms (6) Nucleotides (121) Proteins (29) Interactants (298) Wiki
XB-GENEPAGE-487698
Gene Symbol: htra1

Gene Name: HtrA serine peptidase 1

Synonyms: high temperature required A1 , Xhtra1 , prss11 , xHtrA1 ( Add synonyms , Nomenclature history )

Gene Function: serine protease

Protein Function :
Serine protease with a variety of targets, including extracellular matrix proteins and proteoglycans such as biglycan, syndecan-4 and glypican-4. Through cleavage of proteoglycans, may release soluble ...[+]


Interactants: Loading ...
Disease Ontology: age related macular degeneration 7

OMIM Diseases: MACULAR DEGENERATION, AGE-RELATED, 7; ARMD7 [+]

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Xenbase Gene ID XB-GENE-487699 XB-GENE-17330113 XB-GENE-865727
Gene Symbol htra1 htra1.L htra1.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model
Entrez Gene: 780187
Entrez Gene: 108696094
Entrez Gene: 496061
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq TrEMBL Swiss-Prot NCBI Protein TrEMBL RefSeq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine htra1 htra1.L htra1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HTRA1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Htra1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR htra1a htra1b ZFIN Ensembl
chicken
GEISHA HTRA1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo., Int J Dev Biol 2005                                    
Most Recent The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Development 2015                                      
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 4 terms 6 terms
PANTHER htra1
KEGG Pathways K08784 K08784 K08784
KOG [O] Serine protease
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon Horizon
Morpholino htra1 MO1 htra1 MO1 htra1 MO1
ORF htra1 ORF1 , htra1 ORF2 htra1.S ORF1
Affymetrix 1.0 Str.39179.1.A1_at [+]
Affymetrix 2.0 Xl2.45368.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.3


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