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Summary Expression Gene Literature (411) Nucleotides (94) Proteins (28) Interactants (725) Wiki
XB-GENEPAGE-487723

Gene Symbol: nog

Gene Name: noggin

Synonyms: nog-A, noggin 1, noggin, nog1, noggin-1 Add Xenopus synonyms

Gene Function: extracellular BMP antagonist

Interactants: bmp4(155) , chrd(143) , t(111) , otx2(96) , ncam1(87) , gsc(86) , wnt8a(80) View All

Disease Associations: SYMPHALANGISM, PROXIMAL, 1A; SYM1A [+]
1/7
 
Xenbase Gene ID XB-GENE-487724 XB-GENE-864891
Current JGI Annotation nog nog.L
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq UniProtKB
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene Str.29004 Xl.834
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 29 expression image(s) for tropicalis and laevis
Phenotype tropicalis laevis
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC NOG OMIM:185800 OMIM:184460 OMIM:186500 OMIM:186570 OMIM:611377
mouse
MGI Nog All available mutants
zebrafish
ZFIN nog1
chicken
GEISHA NOG
Publications
First: Dissecting Wnt signalling pathways and Wnt-sensitive developmental processes through transient misexpression analyses in embryos of Xenopus laevis. [Dev Suppl 1992]
Most recent: Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation. [Dev Cell 2015]
View All Papers 78 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular:
      Biological: negative regulation of cell differentiation
      Cellular Component:
EC:
KOG:
Reagents tropicalis laevis
CRISPR / TALEN CRISPR tools CRISPR tools
Clones   EXRC - 2 clone(s)  
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody Nog Ab1 Nog Ab1
Morpholino nog MO1 nog MO1
Affymetrix 1.0 Str.29004.1.S1_at Xl.834.1.S1_at
Affymetrix 2.0 Xl2.834.1.A1_at

Symbol legend[+]

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