nog Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (304)

Nucleotides (92)

Interactants (518)

XB-GENEPAGE-487723

Gene Symbol: nog Gene Name: noggin Synonyms: nog-A, noggin 1, noggin, nog1, noggin-1 Add Xenopus synonyms Gene Function: extracellular BMP antagonist Interactants: bmp4(106) , chrd(97) , otx2(47) , t(47) , wnt8a(45) , gsc(42) , fst(38) View All	1/4

XB-GENE-487724

XB-GENE-864891

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001171898\|Xenopus (Silurana) tropicalis noggin (nog), mRNA ATGGATCATTCCCAGTGCCTTGTGACTATATATGCTCTCATGGTCTTCCTGGGACTTAGAATAGACCAGGGGGGCTGCCAACATTATCTGCACATCAGACCAGCTCCTAGTGAAAACCTACCACTGGTGGACCTTATTGAGCATCCGGATCCTATCTATGATCCCAAGGAGAAGGATCTTAATGAGACCTTGCTGAGGACTTTAATGGTTGGCCACTTTGACCCCAACTTTATGGCCATCAACCTGCCGGAGGAGAGACTTGGAGTGGAGGACCTTGGGGAGTTGGATCTCCTTCTTAGGCAGAAGCCCTCAGGGGCAATGCCAGCAGAAATCAAAGGACTGGAATTTTATGAGGGGCTTCAGGGCAAAAAGCACAGACTGAGCAAGAAACTCAGGAGAAAGTTGCAGATGTGGCTCTGGTCCCAGACCTTCTGTCCTGTCCTTTACACATGGAATGACCTAGGGACCAGGTTTTGGCCTCGCTATGTGAAAGTAGGTAGCTGCTACAGTAAGAGGTCTTGTTCTGTGCCAGAGGGCATGGTTTGCAAAGCTGCCAAGTCTATGCATTTGACCATCTTAAGGTGGAGATGTCAACGCAGGGTTCAGCAGAAGTGTGCATGGATAACCATTCAGTACCCTGTCATATCTGAGTGCAAATGTTCATGTTGA	Refseq >NM_001085644\|Xenopus laevis noggin (nog), mRNA CTAATAAATCCTAAGTAGCCAGAGGGACGAGCTACAGACTGGTTGCGGCGCAGGGTTTATCCAGGGCAGAGAGGAGCAGCAAAAGCACATTGCGCAGCTCTCACTCCCCCTTTCCTTCTGCTTCACTCTATAAGGGCTCCTGCAAATGAAAGAGACCTGCGGGGATTTGCGCGGACAGATGTAAAGGAGATCCTGCAACTTTCTCTGGTTGCATCCCTGGGAGTCGCTGCGCGCCGCTGGCTGATTGCGACTGTTGCTTTCCACAGCTCCCTTCTTCCGCAGTTTCTTCTAGGAGCAGATCGAGTCTCTGGTTACCATGGTGATCGAGCTGAAAGTGAAGAATATTTAAGAGAGGGGAGGCTGGAGCCAGCAGGCAGACAAAGTGGTGCCACCAAGGACTGTGCGTAAAGGGTGAGCGCATTGGAGACAGACAGGGGCTCTGCTGAACTTCCACTTGACTGCGATGAGAGGGGGGAATCCCCAATTCGCTAGGTGCCCCTGAACCCCCCAGAATTCCTCCTCTGATGCATTATTTATGATCTCTGGCAAGAAATCGGGAGCACCCAACTCTTATTTTGTGCAGCTGTGTGCAGCATGGATCATTCCCAGTGCCTTGTGACTATATATGCTCTGATGGTCTTCTTGGGACTTAGAATAGACCAAGGGGGTTGCCAACATTATCTGCACATCAGACCGGCTCCTAGTGAAAACCTACCACTGGTGGACCTTATTGAGCACCCGGATCCCATCTATGATCCCAAGGAGAAGGATCTTAACGAGACCTTGCTGAGGACTTTAATGGTTGGACACTTTGACCCCAACTTTATGGCCACCATCCTGCCAGAGGAGAGACTTGGAGTGGAGGACCTTGGGGAGTTGGATCTCCTTCTTAGGCAGAAGCCCTCGGGGGCAATGCCAGCGGAAATCAAGGGACTGGAGTTTTACGAGGGGCTTCAGAGCAAAAAGCACAGACTGAGCAAGAAACTCAGGAGAAAGTTGCAGATGTGGCTCTGGTCCCAGACCTTCTGTCCTGTCCTTTACACATGGAATGACCTAGGGACCAGGTTTTGGCCTCGCTATGTGAAAGTAGGGAGCTGCTACAGTAAGAGGTCTTGTTCTGTGCCAGAGGGCATGGTTTGCAAAGCTGCCAAGTCTATGCATTTGACCATCTTAAGGTGGAGATGTCAACGCAGGGTTCAGCAGAAGTGTGCGTGGATAACCATTCAGTACCCTGTCATTTCCGAGTGCAAATGCTCATGCTGAGACTCTTGGACTAATGCAAAAAGACAGTAGCTTCATGGTTCAAGCTTCATGTTATATGCACTGTAATATGTAGAAATGTATATGTGTGTATATATGGCATTGGTCTAAATTACTATTAAAAGGTCAGTATTATTCTTTTAAATAACCAGTGTCTACTGTATTTCCAACACTATTATCCTGGTTGTGTTTTATTTTAATAATATTATTATTATTTTTTTTTTGCCTAATGTATCTCTATTTATATCCAAAAAAAGAGCACTTCGCTTGGCGAAGCATTTTTTTTTAAAGAAAAAAAAAACAAATTTAATAGTTTAATAATATAGAAGCATTTTTTTCCTTTAATGGAAAATGTGCCTTTTTTTGATGGACCTCAAAAAAAAAATGAATAAAAACCAGAGCAAGATATAATTTTCAGTTTATTGTACATAGAAAGAGAACACATTTTGAAAGATGAAAAATTTTACTCTTGTAAATGAGAACTATCTGCTATTTATTCTTTTATTTTTTTTTTCCTCCCCCTGTAGAGTGCAGAATAAAAGTAAACCACTAAAATATTAAAAAAAAAAAAAAA
Protein		Refseq >NP_001165369\|noggin [Xenopus (Silurana) tropicalis] MDHSQCLVTIYALMVFLGLRIDQGGCQHYLHIRPAPSENLPLVDLIEHPDPIYDPKEKDLNETLLRTLMVGHFDPNFMAINLPEERLGVEDLGELDLLLRQKPSGAMPAEIKGLEFYEGLQGKKHRLSKKLRRKLQMWLWSQTFCPVLYTWNDLGTRFWPRYVKVGSCYSKRSCSVPEGMVCKAAKSMHLTILRWRCQRRVQQKCAWITIQYPVISECKCSC	Refseq >NP_001079113\|noggin precursor [Xenopus laevis] MDHSQCLVTIYALMVFLGLRIDQGGCQHYLHIRPAPSENLPLVDLIEHPDPIYDPKEKDLNETLLRTLMVGHFDPNFMATILPEERLGVEDLGELDLLLRQKPSGAMPAEIKGLEFYEGLQSKKHRLSKKLRRKLQMWLWSQTFCPVLYTWNDLGTRFWPRYVKVGSCYSKRSCSVPEGMVCKAAKSMHLTILRWRCQRRVQQKCAWITIQYPVISECKCSC UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.29004	Xl.834
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		22 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	NOG	OMIM:185800 OMIM:184460 OMIM:186500 OMIM:186570 OMIM:611377
mouse		MGI	Nog	All(2) Targeted, other(2)
zebrafish		ZFIN	nog1

Publications
First:		Dissecting Wnt signalling pathways and Wnt-sensitive developmental processes through transient misexpression analyses in embryos of Xenopus laevis. [Dev Suppl 1992]
Most recent:		Klf4 is required for germ-layer differentiation and body axis patterning during Xenopus embryogenesis. [Development 2012]
		View All Papers 48 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:		negative regulation of cell differentiation
Cellular Component:
EC:
KOG:

Reagents		tropicalis	laevis
Clones			EXRC - 2 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.29004.1.S1_at	Xl.834.1.S1_at
Affymetrix 2.0			Xl2.834.1.A1_at

Symbol legend[+]