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XB-GENEPAGE-487723
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Gene Symbol: nog
Gene Name: noggin Synonyms: nog-A , noggin 1 , noggin , nog1 , noggin-1 , Noggin1 ( Add Xenopus synonyms , Nomenclature history ) Gene Function: extracellular BMP antagonist Protein Function  :
Patterns the embryo by interrupting bone morphogenetic proteins (BMP) signaling. Binds BMP-4 and BMP-2 with high affinity. Can abolish BMP-4 activity by blocking binding to cognate cell-surface recepto...[+]
Interactants: Loading ... 
Disease Ontology: PROXIMAL SYMPHALANGISM OMIM Diseases: SYMPHALANGISM, PROXIMAL, 1A; SYM1A |
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1/7 | Xenbase Gene ID | XB-GENE-487724 | XB-GENE-864891 | XB-GENE-17332089 | ||||
| Gene Symbol | nog | nog.L | nog.S | ||||
| Chromosome | Chr10 | chr9_10L | Scaffold27 | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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| Protein
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Refseq
TrEMBL
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Refseq
Swiss-Prot
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Genomic Synteny | Genomicus PANTHER | ||||||
| Expression | Development Stages | Embryonic Tissues | Adult Tissues | ||||
| Summary for |
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| More Information |
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| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | nog | nog.L | nog.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| mouse |
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| zebrafish |
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| chicken |
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| fruit fly |
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| Publications | |||||||
| First | Dissecting Wnt signalling pathways and Wnt-sensitive developmental processes through transient misexpression analyses in embryos of Xenopus laevis., Dev Suppl 1992 | ||||||
| Most recent |
Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis., Dev Biol 2018 
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| All | View All Papers 83 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology | ||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 9 terms | 6 terms | 0 term | ||||
| PANTHER | nog | ||||||
| KEGG Pathways | K04658 | K04658 | |||||
| KOG | |||||||
| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | EXRC - 2 clone(s) | ||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Antibody | Nog Ab1 | Nog Ab1 | |||||
| Morpholino | nog MO1 , nog MO2 | nog MO1 , nog MO2 | nog MO1 , nog MO2 | ||||
| Affymetrix 1.0 | Str.29004.1.S1_at | Xl.834.1.S1_at | |||||
| Affymetrix 2.0 | Xl2.834.1.A1_at | ||||||
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