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Summary Expression Gene Literature (504) GO Terms (11) Nucleotides (95) Proteins (32) Interactants (1595) Wiki
XB-GENEPAGE-487723
Gene Symbol: nog

Gene Name: noggin

Synonyms: nog-A , noggin 1 , noggin , nog1 , noggin-1 , Noggin1 ( Add synonyms , Nomenclature history )

Gene Function: extracellular BMP antagonist

Protein Function :
Patterns the embryo by interrupting bone morphogenetic proteins (BMP) signaling. Binds BMP-4 and BMP-2 with high affinity. Can abolish BMP-4 activity by blocking binding to cognate cell-surface recepto...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: proximal symphalangism [+]

OMIM: SYMPHALANGISM, PROXIMAL, 1A; SYM1A [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER

GEO Series : GSE64551.
1/7
 
Xenbase Gene ID XB-GENE-487724 XB-GENE-864891 XB-GENE-17332089
Gene Symbol nog nog.L nog.S
Chromosome Chr10 chr9_10L Scaffold27
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 493191
373646
108704141
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq TrEMBL RefSeq Swiss-Prot TrEMBL NCBI Protein
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine nog nog.L nog.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NOG OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Nog MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR nog1 ZFIN Ensembl
chicken
GEISHA NOG Ensembl
fruit fly
worm
WORMBASE
Publications
First Dissecting Wnt signalling pathways and Wnt-sensitive developmental processes through transient misexpression analyses in embryos of Xenopus laevis., Dev Suppl 1992  
Most Recent The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Elife 2020                                                          
All View All Papers 84 paper(s) referencing morpholinos 12 paper(s) referencing OMIMs 12 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 6 terms 0 term
PANTHER nog
KEGG Pathways K04658 K04658
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks nog
Antibodies Nog Ab1 Nog Ab1
Morpholinos nog MO1 , nog MO2 nog MO1 , nog MO2 nog MO1 , nog MO2
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.13.0


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