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XB-GENEPAGE-
487723
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Gene Symbol: nog
Gene Name: noggin Synonyms: nog-A , noggin 1 , noggin , nog1 , noggin-1 , Noggin1 Add Xenopus synonyms , Nomenclature history Gene Function: extracellular BMP antagonist Protein Function  :
Patterns the embryo by interrupting bone morphogenetic proteins (BMP) signaling. Binds BMP-4 and BMP-2 with high affinity. Can abolish BMP-4 activity by blocking binding to cognate cell-surface recepto...[+]
Interactants: Loading ... 
Disease Ontology Associations: PROXIMAL SYMPHALANGISM OMIM Disease Associations: SYMPHALANGISM, PROXIMAL, 1A; SYM1A |
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1/7 | Xenbase Gene ID | XB-GENE-487724 | XB-GENE-864891 | XB-GENE-17332089 | ||||
| Gene Symbol | nog | nog.L | nog.S | ||||
| Chromosome | Chr10 | chr9_10L | Scaffold27 | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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| Protein
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Refseq
TrEMBL
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Refseq
Swiss-Prot
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.29004 | Xl.834 | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 36 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | nog | nog.L | nog.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| human |
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| mouse |
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| zebrafish |
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| chicken |
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| fruit fly |
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| Publications | |||||||
| First: | Dissecting Wnt signalling pathways and Wnt-sensitive developmental processes through transient misexpression analyses in embryos of Xenopus laevis. [Dev Suppl 1992] | ||||||
| Most recent: |
Retinoic acid-induced expression of Hnf1b and Fzd4 is required for pancreas development in Xenopus laevis. [Development 2018]
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| View All Papers 83 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontologies | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 9 terms | 6 terms | 0 term | ||||
| PANTHER | nog | ||||||
| KEGG Pathways | K04658 | K04658 | |||||
| KOG | |||||||
| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | EXRC - 2 clone(s) | ||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Antibody | Nog Ab1 | Nog Ab1 | |||||
| Morpholino | nog MO1 , nog MO2 | nog MO1 , nog MO2 | nog MO1 , nog MO2 | ||||
| Affymetrix 1.0 | Str.29004.1.S1_at | Xl.834.1.S1_at | |||||
| Affymetrix 2.0 | Xl2.834.1.A1_at | ||||||
Symbol legend[+]
