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XB-GENEPAGE-487774
Gene Symbol:
frat1
Gene Name: frequently rearranged in advanced T-cell lymphomas 1
Synonyms:
gbp
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gsk binding protein
( Gene Function: Protein Function
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Binds GSK-3 and prevents GSK-3-dependent phosphorylation. Regulates the stability of beta-catenin in embryos. Maternal GBP is required for dorsal-ventral axis formation.
InterPro
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-487775 | XB-GENE-17342041 | XB-GENE-865735 | |||||
Gene Symbol | frat1 | frat1.L | frat1.S | Chromosome | Chr6 | chr6L | chr6S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Entrez Gene |
100491326
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398043
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | frat1 | frat1.L | frat1.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis., Cell 1998 |
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Most Recent |
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation., Nat Commun 2020 ![]() |
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All | View All Papers | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 0 term | 0 term | 2 terms | |||||
PANTHER | frat1 | |||||||
KEGG Pathways | K03096 | K03096 | ||||||
KOG | ||||||||
Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | frat1 | |||||||
ORFs | frat1.S ORF1 | |||||||
Clones | Horizon | Horizon Source BioScience | ||||||
Plasmids | Addgene | Addgene |
Symbol legend:



