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Summary Expression Gene Literature (30) GO Terms (4) Nucleotides (60) Proteins (29) Interactants (344) Wiki
XB-GENEPAGE-487810
Gene Symbol:
nphs1

Gene Name:
NPHS1 nephrin

Synonyms:
nephrin ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane protein, component of slit diaphragm, cell signaling

Protein Function :


InterPro :
GPCR Rhodpsn 7TM , GPCR Rhodpsn , Histamine H3 rcpt , Ig sub2 [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
nephrotic syndrome [+]

OMIM:
NEPHROTIC SYNDROME, TYPE 1; NPHS1

External Links:
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Xenbase Gene ID XB-GENE-487811 XB-GENE-17335666 XB-GENE-487815
Gene Symbol nphs1 nphs1.L nphs1.S
Chromosome scaffold_37 chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100494620
734213
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine nphs1 nphs1.L nphs1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards NPHS1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Nphs1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Nphs1 Ensembl
zebrafish
ZFIN, AGR nphs1 ZFIN Ensembl
chicken
fruit fly
worm
Publications
First Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers., J Biol Chem 2003  
Most Recent Dynamin Binding Protein Is Required for Xenopus laevis Kidney Development., Front Physiol 2019                          
All View All Papers 13 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 0 term 1 terms
PANTHER nphs1
KEGG Pathways
KOG [R] Predicted transmembrane protein of the immunoglobulin family of cell adhesion molecules
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks nphs1
Clones Horizon EXRC Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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