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XB-GENEPAGE-487829
Gene Symbol:
hes4
Gene Name: hes family bHLH transcription factor 4
Synonyms:
Xhairy2
,
hairy2
,
hairy2b
,
Xhairy2b
,
hairy2a
,
XHairy2a
,
hes4a
,
hes4b
,
H2
,
hes4-a
,
hes4-b
( Gene Function: helix-loop-helix transcription factor/transcriptional repressor Protein Function
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Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. Plays a role in the patterning of tissue boundaries. Promotes floor plate development and prechordal plate development. Required for ...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-487830 | XB-GENE-865740 | XB-GENE-6256031 | |||||
Gene Symbol | hes4 | hes4.L | hes4.S | Chromosome | Chr7 | chr7L | chr7S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
394465
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398258
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398579
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | hes4 | hes4.L | hes4.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate., Genes Dev 1994 ![]() |
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Most Recent |
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage., Biol Open 2021 ![]() |
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All | View All Papers 18 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 28 terms | 19 terms | 13 terms | |||||
PANTHER | hes4 | |||||||
KEGG Pathways | K06054 | K06054 | K06054 | |||||
KOG |
[K] Transcriptional repressors of the hairy/E(spl) family (contains HLH)
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | hes4 | |||||||
Morpholinos (on-target & off-target) | hes4 MO1 , hes4 MO2 , hes4 MO4 , hes4 MO5 | |||||||
ORFs | hes4.L ORF1 | hes4.S ORF1 | ||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



