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Summary Expression Gene Literature (97) GO Terms (27) Nucleotides (418) Proteins (42) Interactants (1278) Wiki
Gene Symbol: hes4

Gene Name: hes family bHLH transcription factor 4

Synonyms: Xhairy2 , hairy2 , hairy2b , Xhairy2b , hairy2a , XHairy2a , hes4a , hes4b , H2 , hes4-a , hes4-b ( Add synonyms , Nomenclature history )

Gene Function: helix-loop-helix transcription factor/transcriptional repressor

Protein Function :
Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. Promotes floor plate development and prechordal plate development. Required for lens development as early as the stage of lens field ...[+]

Interactants: Loading ...
Diseases:  External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
Xenbase Gene ID XB-GENE-487830 XB-GENE-865740 XB-GENE-6256031
Gene Symbol hes4 hes4.L hes4.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 394465
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot TrEMBL RefSeq TrEMBL Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine hes4 hes4.L hes4.S
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards HES4 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
MGI, IMPC Eurexpress, MGI, Allen Brain Atlas
fruit fly
First Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate., Genes Dev 1994          
Most Recent Nucleotide receptor P2RY4 is required for head formation via induction and maintenance of head organizer in Xenopus laevis., Dev Growth Differ 2019                        
All View All Papers 18 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 25 terms 18 terms 13 terms
KEGG Pathways K06054 K06054 K06054
KOG [K] Transcriptional repressors of the hairy/E(spl) family (contains HLH)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks hes4
Morpholinos hes4 MO1 , hes4 MO2 , hes4 MO3 , hes4 MO4 , hes4 MO5 hes4 MO1 , hes4 MO2 , hes4 MO3 , hes4 MO4 , hes4 MO5 hes4 MO1 , hes4 MO2 , hes4 MO3 , hes4 MO4 , hes4 MO5
ORFs hes4.L ORF1 hes4.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.13.0

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