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Summary Expression Gene Literature (377) GO Terms (9) Nucleotides (75) Proteins (12) Interactants (1505) Wiki
XB-GENEPAGE- 488038

Gene Symbol: shh

Gene Name: sonic hedgehog

Synonyms: hedgehog , Xhh , sonic hedgehog , X-SHH , xshh , vhh-1
Add Xenopus synonyms , Nomenclature history


Gene Function: intercellular signaling, early embryo patterning

Protein Function:
Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the ful...[+]


Interactants: Loading ...

OMIM Disease Associations: COLOBOMA, OCULAR, AUTOSOMAL DOMINANT [+]
1/9
 
Xenbase Gene ID XB-GENE-488039 XB-GENE-864913 XB-GENE-17341047
Gene Symbol shh shh.L shh.S
Chromosome scaffold_6 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.47115 [+] Xl.866
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 131 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine shh shh.L shh.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SHH OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Shh MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN shha shhb ZFIN Ensembl
chicken
GEISHA SHH Ensembl
fruit fly
worm
WORMBASE
Publications
First: Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. [Cell 1994]
Most recent: Mouth development. [Wiley Interdiscip Rev Dev Biol 2017]
View All Papers 48 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 9 terms 0 term
EC
PANTHER shh
KEGG Pathways K11988
KOG [T] Sonic hedgehog and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino shh MO1 , shh MO2 shh MO1 , shh MO2 shh MO1 , shh MO2
Affymetrix 1.0 Str.40140.2.S1_at [+] Xl.866.1.S2_at
Affymetrix 2.0 Xl2.866.1.S2_at

Symbol legend[+]

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