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Summary Expression Gene Literature (25) GO Terms (21) Nucleotides (111) Proteins (45) Interactants (940) Wiki
XB-GENEPAGE-488066
Gene Symbol:
sox7

Gene Name:
SRY-box 7

Synonyms:
xSox7 ( Add synonyms , Nomenclature history )

Gene Function:
HMG-box transcription factor

Protein Function :
Transcription factor. Binds to the DNA sequence 5'-AACAAT-3'. Acts downstream of vegt and upstream of nodal signaling to promote endodermal and mesodermal differentiation by promoting vegt-induced expr...[+]


InterPro :
Sox C , HMG box dom sf , HMG box dom , Sox7/17/18 central [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-488067 XB-GENE-865761 XB-GENE-17331011
Gene Symbol sox7 sox7.L sox7.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549080
378665
108718295
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sox7 sox7.L sox7.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SOX7 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sox7 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sox7 Ensembl
zebrafish
ZFIN, AGR sox7 ZFIN Ensembl
chicken
GEISHA SOX7 Ensembl
fruit fly
worm
Publications
First Cloning and characterization of Xenopus laevis xSox7 cDNA., Biochim Biophys Acta 1996  
Most Recent Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription., Nat Commun 2020                
All View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 20 terms 11 terms 2 terms
PANTHER sox7
KEGG Pathways K09270 K09270 K09270
KOG [K] HMG-box transcription factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sox7
Morpholinos (on-target & off-target) sox7 MO1 sox7 MO1 , sox7 MO2
Clones Horizon Source BioScience EXRC Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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