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Summary Expression Gene Literature (82) GO Terms (12) Nucleotides (117) Proteins (37) Interactants (959) Wiki
XB-GENEPAGE-488221
Gene Symbol:
ptch1

Gene Name:
patched 1

Synonyms:
XPtc1 , patched , patched1 , Ptc-1 , Ptc1 , X-ptc1 ( Add synonyms , Nomenclature history )

Gene Function:
hedgehog receptor, signal transduction

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
medulloblastoma [+]

OMIM:
MEDULLOBLASTOMA; MDB [+]

External Links:
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Xenbase Gene ID XB-GENE-488222 XB-GENE-17338927 XB-GENE-865776
Gene Symbol ptch1 ptch1.L ptch1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100492061
108714691
398215
mRNA NCBI Nucleotide NCBI Nucleotide RefSeq
Protein RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine ptch1 ptch1.L ptch1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PTCH1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ptch1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ptch1 Ensembl
zebrafish
ZFIN, AGR ptch1 ZFIN Ensembl
chicken
GEISHA PTCH1 Ensembl
fruit fly
worm
Publications
First Wingless and patched are negative regulators of the morphogenetic furrow and can affect tissue polarity in the developing Drosophila compound eye., Development 1995  
Most Recent Smoothened stimulation by membrane sterols drives Hedgehog pathway activity., Nature 2019  
All View All Papers 11 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 12 terms 2 terms 2 terms
PANTHER ptch1
KEGG Pathways K06225 K06225
KOG [T] Membrane protein Patched/PTCH
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ptch1
Antibodies Ptch1 Ab2 , Ptch1 Ab1 Ptch1 Ab2 Ptch1 Ab2 , Ptch1 Ab1
Clones Horizon Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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